Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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X-GAL

Thermo Fisher Scientific

X-GAL (5-Bromo-4-Chloro-3 Indolyl-Beta-D-thiogalactopyranoside) is a chromogenic substrate for Beta-galactosidase that turns blue upon hydrolysis and is regularly used for the blue/white color selection assay. Bacteria with a lac+ phenotype grow as blue colonies on plates containing X-GAL.

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Direct Sample Probe

Thermo Fisher Scientific

The Direct Sample Probe system for the Finnigan TRACE DSQTM, Finnigan FOCUS DSQ, and Finnigan PolarisQ is ideal for qualitative or semi-quantitative analysis of materials that are difficult, if not impossible to elute chromatographically.Product detail:The Direct Sample Probe system for the Finnigan TRACE DSQTM, Finnigan FOCUS DSQ, and Finnigan PolarisQ is ideal for the quick screening of samples or for any application which d…

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siPORT™ NeoFX™ Transfection Agent

Thermo Fisher Scientific

siPORT NeoFX’s lipid-based formulation enables the transfection of siRNA into adherent cells as they are subcultured — without increased cytotoxicity. From start to finish, successful gene silencing experiments can be completed in as little as 24 hours. This streamlined protocol can be adapted to a wide range of cells and experimental designs, including high-throughput applications.

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siPORT™ siRNA Electroporation Buffer/Kit

Thermo Fisher Scientific

Electroporation with an effective buffer and optimized conditions can provide a highly efficient method for transfecting primary and hard-to-transfect cells with siRNAs. The siPORT™ siRNA Electroporation Buffer/Kit can be used with multiple types of electroporators to ensure highly efficient delivery of siRNA into cells while maintaining high cell viability.

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siPORT™ XP-1 Transfection Agent

Thermo Fisher Scientific

siPORT XP-1 is an easy-to-use reagent that efficiently delivers both plasmid DNA and PCR products into a variety of mammalian cell types. Comprised of a proprietary formulation of polyamines, the reagent exhibits low toxicity and can be used both in the presence or absence of serum. siPORT XP-1 is particularly straightforward to use. Reagent/DNA complexes can be added directly to growing cells in serum-containing culture med…

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