Trusted information for laboratory scientists on Anti-Doping Science lab products and techniques on SelectScience, including Hematology, Biochemistry, HPLC and UHPLC, GC / MS.
Bond Elut Cellulose columns utilize a pure microgranular cellulose powder that is packed between two, 20 µm polyethylene frits. The cellulose phase is very stable over a wide pH range and contains an extremely low metal content (Fe and CU content less than 5 ppm).
The Bond Elut Certify extraction cartridge utilizes a packed bed consisting of a special, nonpolar C8 sorbent and a strong cation exchanger (SCX). Certify is most commonly used to extract basic (cationic) drugs from urine and blood, but it is also very effective for extracting a wide range of compounds from a diverse number of aqueous matrices.
Bond Elut Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with nonpolar C8 and strong anion-exchange (SAX) sorbent. It has been optimized for acidic drugs, such as 11-nor-delta-9-tetrahydrocannibinol-carboxylic acid, salicylic acid, ibuprofen, acetaminophen, and other compounds tha…
Bond Elut CH is a midpolarity sorbent that exhibits unique selectivities for certain analytes. When employed as a nonpolar sorbent, CH has the approximate polarity of a C2 sorbent. Bond Elut CH is often a good choice when nonpolar sorbents, such as C18, C8, or C2, do not provide the desired selectivity.
A medium polarity sorbent with many uses, Bond Elut Cyano (CN) is ideal for applications in which extremely nonpolar compounds would be irreversibly retained on high carbon load sorbents, such as C8 and C18. This endcapped version of the cyano sorbent is best utilized when extracting analytes from an aqueous matrix.
Bond Elut DEA bears some resemblance to Bond Elut NH2 in its properties, but with a slightly lower capacity as an anion-exchange sorbent. DEA has a moderately nonpolar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C8, but less polar than C2 or CN-E.
Bond Elut Diol resembles unbonded silica as it is known for strong hydrogen bonding with analytes. 20H can also be employed in the nonpolar mode because the hydrocarbon spacer on its functional group provides enough nonpolar character for retention of hydrophobic analytes. Bond Elut Diol is a listed SPE device for the DIN 14333-1 method on benzimidazole fungicides.
Bond Elut ENV, a PS-DVB polymer, is designed for the extraction of polar organic residues. It contains 125 µm spherical particles with a high degree of cross linking, advantageous for high volume, fast flowthrough applications.
Florisil is a magnesia-loaded silica gel. Like silica, it is extremely polar in nature and ideal for the isolation of polar compounds from nonpolar matrices. The larger particle size of the sorbent enables fast flow for large sample volumes and therefore can be an attractive alternative to silica if the sample matrix is particularly viscous.
Bond Elut LMS polymeric sorbent lets you elute without having to add amine modifiers, buffers, or acids. The elimination of secondary interactions means that elution of analytes can be achieved with pure organic solvents or HPLC mobile phase-compatible solvent mixtures of low ionic strength. These characteristics are crucial to allow compatibility with LC/MS or other delicate analytical techniques.
