Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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DILI Assay

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…

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EPP (Endocrine Profiler Panel)

Thermo Fisher Scientific

The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…

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Advanced High Resolution 2-colour Fluorescence Microarray Scanner: InnoScan 910

Innopsys

Performance, Resolution, Speed. With its new detection system, the InnoScan 910 has the highest resolution and reading speed on the market. This user-friendly, two-color scanner is the ideal tool for reading current and future high-density microarrays.With outstanding sensitivity and signal-to-noise ratio derived from its highly regarded photometric properties, the InnoScan 910 is a confocal detection scanner fitted with 2 ex…

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Analysis Software for Microarray Images: Mapix

Innopsys

Simple, User-friendly, High performance.Mapix is characterised by its ease-of-use. It is a standard in the field of segmentation (automatic searching for microarray spots). Mapix has the most up to date requirements to browse data from microarray experiments quickly, with a high level of reliability and optimised productivity.Mapix can be customized, allowing users to add their own functions using its exclusive plug-in system.…

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TIGRIS® DTS™ System

GEN-PROBE Inc.

Absolute Automation Is True Walk-Away Freedom for: ■ Sample Preparation ■ Sample Processing ■ Results Analysis Only the TIGRIS® DTS™ System, with Absolute Automation, automates all phases of molecular diagnostics testing from sample preparation, amplification, and detection to reporting results. Integrating the TIGRIS DTS System with APTIMA® assay kits for nucleic acid testing (NAT) offers true freedom from hands-on processing…

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AbsoluteIDQ® p150 Kit

BIOCRATES Life Sciences AG

The AbsoluteIDQ p150 Kit identifies and quantifies 163 analytes from 4 compound classes, i.e., acyl carnitines, amino acids, glycerophospho- and sphingolipids and hexose using an FIA-MS/MS method.The p150 Kit is an excellent choice for researchers who are looking for a cost-effective solution to measure metabolites under quality-controlled conditions in their own laboratory. The AbsoluteIDQ® p150 Kit is an easy-to-use and accu…

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AbsoluteIDQ® p180 Kit

BIOCRATES Life Sciences AG

The AbsoluteIDQ p180 Kit enables standardized, quantitative and reproducible analysis of ca. 200 endogenous metabolites from several metabolite classes (acyl-carnitines, amino acids, biogenic amines, (lyso-) phosphatidylcholines, sphingomyelins, hexoses, steroids). The metabolite analysis is based on flow injection analysis (FIA-ESI-MS/MS) and LC-ESI-MS/MS. The possibility of measuring different biological matrices of differe…

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Metabolic Phenotyping Services

BIOCRATES Life Sciences AG

Through these Metabolic Phenotyping Services we can help you to identify relevant metabolic biomarkers, accelerate your understanding of biochemical pathways and provide important information of the metabolomic state of a cell, tissue or living organism. Our technology platform offers mass spectrometry-based (FIA-, LC-MS/MS and GCMS) quantification of metabolites through multiple reaction monitoring (MRM) using triple quadrup…

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R'ALF: Autoclaveable Benchtop Fermentor

BiOENGiNEERiNG

The ultimate standard for autoclaveable bench-top fermentor systems Comes with all necessary controls and accessories for fermentation or cell culture Can operate in continuous, batch, and fed-batch modes Size range: 2.0-7.0 L Option to run up to 6 fermentors at a time from one station with our state-of-the-art BiOSCADA software system: offering countless options for control strategy, process engineering, and data manag…

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NLF: Small Pilot Fermentor

BiOENGiNEERiNG

The flexible & mobile laboratory fermentor for cultivation excellence: Designed for laboratory or small-scale production purposes In-situ sterilizable, with electrical heating system or steam heat exchanger As a modular system with glass or steel cylinders, can readily adapt to a wide variety of needs with minimum hassle Can operate in continuous, batch, and fed-batch modes Available as a cGMP fermentor for small-s…

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LP: Laboratory or Production Fermentor

BiOENGiNEERiNG

The perfect link between laboratory and production: Designed for scale-up or production processes User-friendly and open-frame construction allows for easy installation and maintenance of this in-situ sterilizable fermentor, with steam heat exchanger Modular design gives flexibility when choosing controls and accessories for any biotechnological process. Size range: Choose from an option of 42L, 50L, or 75L stainless…

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P: Pilot Fermentor

BiOENGiNEERiNG

The pilot-scale fermentor for production perfection: Our largest off-the-shelve fermentor, in-situ sterilizable for use in pilot and production plants Straight-forward and user-friendly design, with flexible controls and accessories for whatever performance you are looking to achieve Size range: Total volume size ranging from 100L to 1000L and possibly beyond Controlled by our state-of-the-art BiOSCADA software: offer…

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Stability Program Software Application

Novatek International

The Stability Program Software Application is a software application that manages the day-to-day activities of the stability department within the quality control and/or R&D divisions. Its design takes into consideration the latest guidelines from the FDA, TPP, ICH and EU, among others, pertaining to pharmaceutical, chemical, biological and biotechnological fields. This software is designed for all types of products, from pre-…

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DropArray™ Accelerator HT200

Curiox

The DropArray™ Accelerator HT200 allows higher level of automation for researchers. It provides similar benefits to DropArray™ Accelerator LT100 with additional features required for our high throughput and screening customers. The HT200 is a fully automated washing instrument that can be easily integrated into existing liquid handling systems, and is compatible with traditional plate formats used in imagers and dispensers. It…

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DropArray™ Accelerator LT

Curiox

The DropArray™ Accelerator LT is the first in a series of products offered by Curiox. The Accelerator LT targets users in research labs performing ELISA and cell adherent assays. The DropArray™ Accelerator is a bench-top liquid handling station that automates the wash step in wash-based bioassays (bioassays that require a wash step in between addition of reagents) by eliminating conventional tedious and long drawn pipetting me…

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Corning® 96-well Flat Clear Bottom White Polystyrene TC-treated Microplates, 20 per Bag, with Lid, Sterile

Corning Life Sciences

White walled plates enhance luminescent signals and have low background luminescence and fluorescence Bottoms are 60% thinner than conventional polystyrene plates, resulting in lower background fluorescence and enabling readings down to 340nm Opaque walls to prevent well-to-well crosstalk Optically clear flat well bottom permits direct microscopic viewing Can be used for both top and bottom reading instruments Flat bott…

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BluePippin Size Selection System

Sage Science

The BluePippin is a preparative electrophoresis platform for collection of size-selected DNA or protein samples. The system automates DNA or protein size selection using disposable, pre-cast agarose cassettes to extract fractions according to user-defined software input. Samples are electro-eluted from agarose and collected in buffer. The platform is used for the construction of next-gen sequencing libraries, or upstream of p…

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StemXVivo™ Osteogenic Supplement

Bio-Techne

Product Description The StemXVivo Osteogenic supplement is a media supplement for the differentiation of human mesenchymal stem cells (MSCs) into osteocytes. All the components have been selected and optimized for human MSC osteogenesis. This product does not contain antibiotics. Intended Use StemXVivo Osteogenic Supplement is designed to be used with StemXVivo Osteogenic Base Media(R&D Systems, Catalog # CCM007) for the desir…

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Human Multipotent Mesenchymal Stromal Cell Multi-Color Flow Cytometry Kit

Bio-Techne

Product Description This kit contains four conjugated antibodies (and corresponding isotype controls) that can be used for single-step staining of human multipotent mesenchymal stromal cells (hMSCs) (1 - 4): Positive Markers • CD105-PerCP (Clone 166707; mouse IgG1) • CD146-CFS (Clone 128018; mouse IgG1) • CD90-APC (Clone Thy-1A1; mouse IgG2A) Negative Marker • CD45-PE (Clone 2D1; mouse IgG1) This kit also contains Staining Buf…

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Channeltron® Electron Multipliers

Photonis

PHOTONIS Channeltron detectors provide the highest sensitivity due to superior signal collection and noise reduction, effectively improving the efficiency of your mass spectrometer. With over 150 replacement detectors to choose from, we can supply the replacement detector in a wide range of mass spectrometers, even if the instrument is no longer manufactured. Additionally, many of our detectors can be bought as complete repl…

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Advanced Performance Detectors

Photonis

PHOTONIS’ Advanced Performance Detectors (APDs) are plug-and-play electo-optic assemblies which provide a complete housing, facilitating manufacturing assembly, repair or replacement to mass spectrometers and other machines. Available for new machines or as replacement cartridges for existing models, over 200 types, with cartridge-mounted MCP, further simplifying additional repairs. ¶PHOTONIS Advanced Performance Detectors (AP…

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Gen2 UltraFast™ TOF Detectors

Photonis

PHOTONIS offers the widest and most technologically advanced variety of Time-of-Flight Detectors available. These patented detectors offer previously unobtainable levels of temporal resolution, dynamic range, and high mass detection sensitivity for TOF Mass Spectrometry. PHOTONIS' unique 2-Micron pore MCP provide the highest channel density of any MCP providing gains in excess of 5x106. PHOTONIS manufactures Time-of-Flight Det…

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