Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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6875 Freezer/Mill®

SPEX SamplePrep, LLC

The 6875 Freezer/Mill® is a large cryogenic mill that accommodates sample sizes ranging from 0.1 - 100 grams. Specifically designed for cryogenic grinding and pulverizing tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. The new high resolution display is user-friendly and shows the each stage of the grinding process. It also shows the Run history, Training videos and manuals and a…

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6875D Freezer/Mill®

SPEX SamplePrep, LLC

The 6875D Freezer/Mill® is a high-throughput, dual chamber cryogenic grinder with a self-contained liquid nitrogen tub and insulated case. Specifically designed for cryogenic grinding and pulverizing of tough and/or temperature sensitive samples in a grinding vial immersed in liquid nitrogen. This mill chills samples in liquid nitrogen then pulverizes them with a magnetically driven impactor. The new high resolution displa…

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VersaMAP™ Development System

Bio-Techne

The VersaMAP Development System offers our widest selection of potential analytes for Luminex-based multiplexing. The diluent supplied is suitable for most cell culture supernate samples. Samples with complex matrices, such as serum and plasma, may need further optimization. For multiplex kits validated by R&D Systems for use in complex matrices, please see our Fluorokine® MAP products. VersaMAP Development System product data…

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Fluorokine® Multianalyte Profiling (MAP) Kits

Bio-Techne

Fluorokine MAP Kits for the Luminex platform are highly efficient multiplex assays that have been validated for the quantification of factors in complex matrices and require little or no optimization. For a wider selection of analytes, please see our VersaMAP™ line of development kits validated for use with cell culture supernatants. Features Simultaneously detect multiple analytes Requires small sample volume (Undergoes simil…

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VersaMAP™ Magnetic Custom Multiplex Kits

Bio-Techne

The VersaMAP™ Magnetic Custom Multiplex Kits are our most efficient Luminex-based multiplex assays. These homogeneous, no wash assays utilize analyte-specific antibodies conjugated to superparamagnetic microparticles to simultaneously detect up to 25 user-defined phosphorylated receptor tyrosine kinases (RTKs) in a single sample. Available Kits VersaMAP Magnetic Human RTK Kit A VersaMAP Magnetic Human RTK Kit B Features • Comp…

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PGN003 PureGenome™ Next Generation Sequencing Library Amplifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN002 PureGenome™ Next Generation Sequencing Library A-Tail Enhancer

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN001 PureGenome™ Next Generation Sequencing Library DNA Modifier

Merck

The PureGenome™ High Efficiency Next Generation Sequencing (NGS) Library Preparation Reagents are uniquely optimized as a one-stop solution for NGS Library Preparation. Validated for sequencing compatibility with Illumina® instruments; three sets of reagents are offered each having a unique functionality in the library preparation work flow. The PureGenome NGS Library DNA Modifier, when purchased with the PureGenome NGS Librar…

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PGN004 PureGenome™ Next Generation Sequencing Library Validator Kit

Merck

The quality of sequence obtained from Next Generation sequencing platforms such as Illumina, Inc. requires the accurate determination of input library DNA. Loading too much DNA can lead to overlapping clusters and loss of read counts whereas too little input can lead to poor read lengths and lower sequence output. The PureGenome™ NGS Library Validator Kit measures the absolute amount of adapter-ligated, sequence ready DNA in I…

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PureGenome™ On-Spot Tissue DNA Kit

Merck

The PureGenome™ On-Spot Tissue DNA kit allows for convenient isolation of genomic DNA in any targeted microscopic tissue area on a slide. The system combines a powerful area-specific tissue sampling technology with a one-step DNA extraction method and makes targeted tissue genomic DNA isolation easy and simple. The kit efficiently recovers genomic DNA from paraffin archives or fresh tissue sections for PCR analysis. Unlike a c…

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PureGenome™ Tissue DNA Extraction Kit

Merck

The PureGenome™ Tissue DNA Extraction Kit is a simple procedure for the rapid isolation of total DNA (e.g. genomic, mitochondrial, parasitic, microbial, viral) from a variety of soft and solid tissues, cells and a range of biological liquids. This product has been optimized for maximal recovery of ultra-pure DNA without RNA contamination and is also compatible with buffy coat, bone marrow, cells from culture, whole blood (fres…

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NovaSeptum Sampling System

Merck

A sterile, closed, disposable system for sampling fluids from sterile and aseptic processes The unique NovaSeptum sampling system is ideal for general fluid and cell culture sampling from aseptic and sterile processes. Both systems can be configured for high purity or autoclavable sampling applications and as single or multiple sampling units. A wide range of holders and connectors are also available. •  Closed sampling elimin…

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easyPunch STARlet - Automated Sample Punching and Processing

Hamilton Company

For DMPK sample card punching and pipetting. The easyPunch STARlet consists of a STARlet Autoload liquid handling workstation comprising 4 ndependent 1 ml channels, a card and plate gripper and the punch module.  computer with Hamilton enus software and 4 specific predefined methods is included as well.The system can be used for a variety of different applications e. g. forensic reference databasing, MPK and toxicology studie…

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OneTRAC™ combined service

Plexpress

OneTRAC™ allows you to profile every gene, validate biomarker signatures, and apply your findings across all your studies. One-stop service for all your gene expression profiling needs All-inclusive gene expression data for pattern recognition and pathway analyses at the macro- and micro-levels Streamlined and integrated methodology from screening to validation of gene signatures Cost-efficient expression profiling f…

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Vena8 Fluoro+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Fluoro+™ biochip is ideal for studying cell receptor-ligand interaction and is compatible with confocal microscopy. As cells flow through the microcapillary of the Vena8 Fluoro+™ biochip, the cell surface receptors may interact with adhesion molecules or ligands which coat the microcapillary walls. Ideal for use with fluorescence immunostaining, confocal microscopy and for applications such as thrombosis.

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Vena8 Endothelial+ Biochip: microfluidic flow chamber

Cellix Ltd

The Vena8 Endothelial+™ biochip is ideal for studying cell-cell interaction. Endothelial cells are easily seeded (via standard pipette) and cultured inside the microcapillaries of the biochip. As cells flow through the microcapillary of the Vena8 Endothelial+™ biochip, the cell surface receptors may interact with the endothelial cell monolayer which coats the microcapillary walls. Ideal for use with phase contrast imaging an…

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SurePrint G3 Gene Expression Microarrays

Agilent Technologies

SurePrint G3 Gene Expression Microarrays offer a comprehensive coverage of genes and transcripts. Superior sensitivity with a wide dynamic range of over 5 orders of magnitude ensures detection of low and high expressors for the most biologically relevant data. With the newest Gene Expression v2 Microarray, new large intergenic non-coding RNA (lincRNA) probes designed to the human catalog of lincRNAs from the Broad Institute al…

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Syncerity 1024 x 256 CCD Detector

HORIBA Scientific

The deep cooled Open Electrode 1024 x 256 CCD Camera combines affordability, performance and versatility for both Research and OEM applications. With peak UV QE at 32% and peak VIS-NIR at 58%, SyncerityTM offers a relatively flat response and addresses multiple applications. In the near-NIR, this detector is a lower cost alternative to the deep depletion CCD, with no etaloning. The dynamic range of this SyncerityTM camera is u…

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