Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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MED64 (MEA System)

KF Technology Srl

A low-noise multi-electrode array system for in vitro extracellular electrophysiology. The MED64 is a user-friendly multi-electrode array (MEA) system for stimulation and recording of field potentials (extracellular signals) from different areas within a biological sample over hours, days, weeks and even months. Acute or cultured biological preparations are placed or grown directly on a grid of 64 planar microelectrodes, whic…

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Brain Slice Chamber Model BSC

KF Technology Srl

These slice recording chambers are designed to maintain isolated, living tissues in vitro in "interface" mode and allow stable electrophysiological recordings to be made from the preparation. The temperature is controlled by a proportional control heating unit.

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Bioscan BioFLECT™ 400

Bioscan Inc.

The new Bioscan BioFLECT 400 is the first in vivo optical imaging system offering true 360° fluorescence tomography. BioFLECT uses the photon emission data acquired from 360° and a state-of-the-art 3D reconstruction engine to quantitatively reconstruct the 3D spatial distribution of fluorescent probes in live animals. This approach yields superior, consistent resolution, sensitivity and quantitation throughout the subject. The…

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Ultima Multiphoton In Vivo Extended Reach Microscope

Prairie Technologies

The Ultima In Vivo Extended Reach builds upon the In Vivo clearance to provide an even larger area for researchers using larger animals for their imaging models. Mounted on posts that are fixed or movable, the user can choose to move the sample or the microscope itself. Scanheads with the standard imaging galvos and the optional uncaging galvos allow for simultaneous imaging and uncaging using two lasers. Prairie View softwa…

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Lago

Spectral Instruments Imaging

Spectral Instruments Imaging's LAGO offers high throughput imaging for BLI & FLI. With 10 mouse campacity, the LAGO is a fantastic option for high volume imaging cores. This workhorse is designed for non-stop imaging and is the gold standard in sensitiviy - 36% more sensitive than the leading competitor. The LAGO also provides Absolute Calibration, -90C Air Cooled CCD Camera, LED Fluorescence excitation and free software.

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Perfecta3D Hanging Drop Plates - 384-Well

3D Biomatrix

The patent-pending Perfecta3D® Hanging Drop Plates are 96- and 384-well plates that facilitate the formation, culture, and testing of three-dimensional (3D) spheroids and stem cell aggregates without the aid of coatings or matrices. With only one spheroid forming in each well, 3D spheroids formed in Perfecta3D Hanging Drop Plates are consistent and diameter can be controlled by the number of cells seeded in each well. Media…

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FLS980-sm: Combined Steady State and Phosphorescence Lifetime Fluorimeter

Edinburgh Instruments Ltd.

The FLS980-sm is the world’s most sensitive modular, computer controlled spectrofluorimeter offering combined steady state and phosphorescence capabilities. Combining ultimate sensitivity with high spectral resolution and excellent stray light rejection, the FLS980-sm can measure lifetimes from 1microsecond to 10 seconds. Features Include: Lifetimes from 1 microseconds to 10 seconds. Automated spectral correction PC plug-in ca…

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FLS980-s: Sensitive Spectrofluorimeter - Steady State

Edinburgh Instruments Ltd.

The FLS980-s is the world’s most sensitive modular, computer controlled spectrofluorimeter.Features Include: • Guaranteed S/N ratio of >12000:1 • Count rates of up to 100MHz Resolution from 0.05 – 18nm • Stray Light Suppression of 1 x 105 (1 x 1010 optional) • Automated spectral correction Complete PC control The FLS980-s is a modular, computer controlled L - geometry spectrometer for acquiring steady state luminescence spectr…

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FLS980-m: A Complete Fluorescence, Phosphorescence Laboratory in one Instrument

Edinburgh Instruments Ltd.

The FLS980-m is the world’s most sensitive modular, computer controlled spectrofluorimeter offering phosphorescence capabilities. Combining ultimate sensitivity with high spectral resolution and excellent stray light rejection, the FLS980-m can measure lifetimes from 1 µs to 10 seconds.Features Include: • Count rates of up to 100MHz • Lifetimes from 1µs to 10 seconds • Resolution from 0.06 (with 1800g/mm grating) • Stray Light…

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FLS980-t: High Performance Fluorescence Lifetime Spectrometer

Edinburgh Instruments Ltd.

The FLS980-t is s the world’s most sensitive modular, computer controlled fluorescence lifetime spectrometer. Based on an L - geometry hardware configuration, the FLS980-t utilises the technique of Time Correlated Single Photon Counting (TCSPC) to measure time resolved luminescence spectra and luminescence lifetimes spanning the range from 100picoseconds to 10microseconds, with the accuracy and the resolution that only the tec…

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Snap Seal™ Vials and Snap Top Caps™ for the 96 Well Multi Tier™ Micro Plate System

J.G. Finneran Associates, Inc

Patented sample vials and closures form a sealing system for use with autosamplers and robotic equipment Chemists can secure samples in a snap with a new system for automated high-throughput sampling. J.G. Finneran Associates, a manufacturer and supplier of unique and innovative products for the global chromatography, biotechnology, and environmental research communities, has adapted its Snap Seal Vials and 8mm Precision Fit S…

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CellBase CT - for ex-vivo expansion of autologous cell therapy products

TAP Biosystems

CellBase CT is a new automated system designed for ex-vivo expansion of autologous cell therapy products. Developed with leading cell therapy organisations, CellBase CT scales up existing manual cell culture processes in T-flasks, enabling manufacture of cell therapy products derived from a wide range of cell types, including hES, iPS and adult stem cells. CellBase CT automates:CellBase CT automates the maintenance and expansi…

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ProReveal Test

Synoptics Health

Fluorescence Protein Detection Test ProReveal is a highly sensitive fluorescence-based patented protein detection test for checking the presence of residual protein on surgical instruments after going through a washer disinfector process. This cost-effective test (conforms to BS EN ISO 15883-1) delivers objective, visual and measurable results, removing any doubt as to whether a decontaminated instrument is safe for reuse. Ke…

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MultiPep RSi

Intavis Inc.

The MultiPep RSi is a fully automated high throughput multiple peptide synthesizer based on a pipetting robot. Utilizing exchangeable modules, the MultiPep RSi can be configured to enable the synthesis of small scale peptide libraries, membrane bound peptide arrays (SPOT method), specialty peptides or PNAs, as well as high quality peptides in large scales up to 10 mmol. Due to this flexibility, the instrument can take the pl…

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MultiPep CF

Intavis Inc.

The MultiPep CF is a fully automated peptide synthesizer with a unique column module that allows the synthesis of long and difficult sequences. During the synthesis, reagents are continuously circulated and real time UV monitoring enables the automatic optimization of reaction parameters like deprotection, coupling times, and wash steps. This leads to a greater coupling yield, superior peptides, and also saves time and reduc…

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Liquid Crystal Tuneable Optical Filter

Laser Physics UK Ltd

Meadowlark Optics’ Liquid Crystal Tuneable Optical Filters facilitate spectral analysis of not only a collimated beam, but of an entire object. With no moving parts, a resolution down to 0.001nm and a tuning rate of less than 100ms, these robust filters are calibration free and can replace literally 1000s of filters for applications including fluorescence and absorption microscopy, Raman spectroscopy and solar astronomy. At 38…

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Spatial Light Modulator

Laser Physics UK Ltd

Meadowlark Optics manufactures a range of world leading Spatial Light Modulators (SLMs) providing precision beam control. The 2-dimensional Hex series are designed for adaptive optics applications as real-time programmable phase mask for wave front correction, such as a variable iris with no moving parts. With its high optical power handling characteristics, the Linear SLM can be used to alter the temporal profile of femto sec…

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Photomultiplier

Laser Physics UK Ltd

The Photomultiplier is a turnkey detector with a low noise, high sensitivity system that exceeds the performance of silicon photodiode systems over the wavelength range 185 to 800nm. It has a superior combination of a large, 8mm diameter, aperture and fast response of 10 microseconds. The convenient controller provides 11 gain seconds over an amplification range of 102 to 106 and includes a detector overvoltage protection circ…

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Argon Laser Heads

Laser Physics UK Ltd

Modu-Laser's Aries Series Argon Laser Systems provide a drop in solution for many applications currently using Spectra-Physics ™ 163 laser systems and JDSU ™ 2211 laser systems. In addition, the Aries series argon laser system is ideal for many applications which require a vertical laser head cooling configuration.

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Kingfisher V

Raptor Photonics

Using the new Sony ICX694 chip, offering 6MP resolution, the Kingfisher V has 4.54μm x 4.54μm pixels enabling ultra sharp image resolution and QE of up to 77%. The extremely low dark current is achieved by cooling to Δ -111°C allows long exposure times and extremely low dark current of 0.000001 e/p/s and readout noise of less than 1.5 electrons (Global shutter) makes it the perfect camera for staring applications. The Kingfish…

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HyCryo™ Cryopreservation Media

Thermo Fisher Scientific

Thermo Scientific™ HyCryo Cryopreservation Media is a serum-free, animal origin-free product intended for cryogenic storage of your standard cell lines. HyClone™ HyCryo media is a serum-free, animal origin-free product intended for cryogenic storage for your standard cell lines. HyCryo gives you the recovery that you want from your cells with peace of mind knowing that your precious cells are faithfully preserved for your futu…

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HyCryo-STEM™ Cryopreservation Media

Thermo Fisher Scientific

Thermo Scientific™ HyCryo-STEM is designed specifically for stem cells, with a serum-free formulation that maintains differentiation potential and minimizes spontaneous differentiation of stem cells. HyCryo-STEM provides impressive cell recovery and post-thaw growth of pluripotent stem cells (ESC and iPSC) and neural progenitor cells such as mouse cortical stem cells (MCSCs) and rat cortical stem cells (RCSCs). The serum-free…

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Pippin Pulse Electrophoresis Supply

Sage Science

The Pippin Prep is a preparative electrophoresis platform for collection of size-selected DNA samples. The system automates DNA size selection using disposable, pre-cast agarose cassettes to extract fractions according to user-defined software input. Samples are electro-eluted from agarose and collected in buffer. The platform is used for the construction of next-gen sequencing libraries. The system collects fragments (depend…

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Pippin Link Group Controller

Sage Science

The Pippin Link Group Control is the best way to reproducibly provide the highest quality size-selected DNA in high-throughput. It provides hardware and software for running up to eight Pippin Instruments from a laptop PC. Three linked-Pippins can produce up to 96 size selections in one day.

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WHEATON® Integrated Biobanking System

WHEATON

WHEATON BioBanking Solutions is a comprehensive offering of high quality products and customized services for your cryogenic needs.Whether you require the storage of irreplaceable samples in glass cryogenic ampules or plastic cryogenic vials, bar coding options for sample traceablity or for color coded storage and freezer boxes, WHEATON provides you with the tools that make your job easier and more efficient while having the c…

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