Drug discovery > Basic Research Products & Reviews

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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Disposable Cuvettes for Spectroscopy

Kartell S.p.A.

Disposable cuvettes for spectrophotometry, optical PS visible range cuvettes, UV Grade PMMA cuvettes. Standard and semi-micro disposable cuvettes for spectroscopy made of optical PS and PMMA UV grade optical windows to achieve optimal transmittance through spectral range from 340 to 800 nm (OPS) an from 280 to 800 nm (PMMA UV qrade). The engineering and quality control determine the reproducibility of the cuvettes. These are s…

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PELCO® STEM Imaging Holder

Ted Pella Inc.

The PELCO® STEM imaging holder enables STEM imaging in the SEM by using the standard Everhart-Thornley SE detector in the SEM chamber. The standard 3mm TEM grid is placed in the grid holder and located under the scanning beam. The STEM image is created by the adjustable Pt conversion plate which must face the chamber SE-detector. Cost-effective method for STEM imaging by using the existing SE detector in the SEM chamber. The i…

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EBSD QuasOr

Thermo Fisher Scientific

Thermo Scientific QuasOr, the no compromise EBSD. Electron Backscatter Diffraction (EBSD) enables nanostructural analysis in the electron microscope by characterizing the crystalline structures which affect physical properties in a wide range of materials. As an integral part of the Thermo Scientific NORAN System 7, simultaneous acquisition of EBSD and EDS/WDS spectral images are performed with ease.

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Strand Specific RNA Library Preparation Kits

Agilent Technologies

The SureSelect Strand-Specific RNA Library Preparation kit prepares Poly(A) enriched libraries for whole-transcriptome sequencing. Sequence a wide range of RNA to detect gene expression changes and alternative splicing. The kit contains mRNA sequencing library preparation and enrichment materials.

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Genomic DNA ScreenTape

Agilent Technologies

Genomic DNA ScreenTape analysis provides fast, automated and reliable electrophoretic separation of input genomic DNA samples. The gDNA ScreenTape assay can separate DNA samples from 200 to more than 60,000 base pairs in less than 2 minutes/sample. Samples can be analyzed from multiple sources including FFPE.

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VenaT4 Biochip

Cellix Ltd

The VenaT4™ biochip model combines Cellix's proprietary microfluidic flow technology for cell recruitment under shear stress with traditional transwell chamber models. Used to investigate and quantify cell recruitment to various ligands in the presence of chemoattractants contained within the microwells mimicking tissue and / or injury sites. The biochips contain 4 microcapillaries in parallel, each with an embedded microporo…

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FlowCellect™ Human NK Cell Characterization Kit

Merck

The FlowCellect™ Human NK Cell Characterization Kit includes three directly conjugated antibodies, Anti-CD3-APC, Anti-CD56-PE, and Anti-CD16 FITC. This three color kit is designed to characterize NK within mixed cell populations. The antibodies provided have been carefully titrated to ensure the ability to accurately measure the expression of all markers simultaneously. Sufficient reagents are provided to perform 25 three-colo…

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UV-Vis Praying Mantis Diffuse Reflectance accessory

Agilent Technologies

The praying mantis diffuse reflectance accessory is useful for measuring the diffuse reflectance of low volumes of powders and pastes. Using two large hemispherical mirrors, it collects the light reflected from the crystalline sample, enabling the full wavelength range of the Cary instrument to be used. The accessory can be used with the Cary 4000, 5000, 6000i, and 7000 instruments.

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QExtra: Quantum Efficiency Enhancing CCD Technology

HORIBA Scientific

HORIBA Scientific introduces QExtraTechnology, an anti-reflective multi-layer coating to significantly improve quantum efficiency over a broad spectral range while suppressing undesirable etaloning effects.QExtraTechnology provides outstanding quantum efficiency for experiments which require coverage from UV to NIR while suppressing etaloning effects noticeable at longer wavelengths in basic back-illuminated deep depleted came…

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DART® Ion Mobility Spectrometer

Photonis

DART® Ion Mobility Spectrometer The new DART® Ion Mobility Spectrometer is a completely integrated benchtop instrument equipped with Resistive Glass technology and improved performance. It provides DART-IMS analysis of solid, liquid or gas analytes quickly and easily for use in homeland security, pharmaceutical or laboratory applications. Sample preparation is easy, and identifiable results can be seen in less than 10s. The…

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Variant Analysis

Ingenuity Systems Inc.

Identify causal variants from human sequencing data in just hours Rapidly Identify and Prioritize Variants Ingenuity Variant Analysis combines analytical tools and integrated content to help you rapidly identify and prioritize variants by drilling down to a small, targeted subset of compelling variants based both upon published biological evidence and your own knowledge of disease biology. Biological Interpretation of your Var…

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SmartFlare RNA Detection Probes

Merck

SmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle techno…

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CytoSure™ Genomic DNA Labelling Kits

Oxford Gene Technology Ltd

The labelling of DNA samples used in array comparative genomic hybridisation (aCGH) is a critical step in the experimental process as poor labelling can result in inaccurate data. OGT’s CytoSure Genomic DNA Labelling Kits have been uniquely developed and optimised to enable rapid delivery of high quality results with high signal-to-noise ratios.

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CytoSure™ Cancer +SNP Array

Oxford Gene Technology Ltd

Reliable detection of copy number changes and loss of heterozygosity on a single array for haematological malignancies and solid cancers. The CytoSure Cancer +SNP array delivers: ■ Flexible choice of reference sample ■ Confident detection of CNV and LOH on a single array ■ An optimised design allowing identification of key genomic aberrations ■ Cancer-specific tracks enabling fast and easy data generation and interpretation o…

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HyperVision HPV-X

In a variety of scientific applications, phenomena elapse in an instant, leaving no clue to their solution. High-speed video cameras record such moments, enabling visualization through slow-motion replay. This technology is used as an important analysis tool in a variety of fields including materials failure, electric discharge, explosions, and microscopic phenomena. In recent years, such observations have progressed to ever…

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Objective Heater

Okolab

The Okolab Objective Heater is made by a flexible heating collar with a built in temperature sensor, which can be easily fastened around the objective with the supplied Velcro tape. The heating collar can be controlled by a Top Stage Bold Line Temperature controller, by UNO or by the Okolab Stand Alone Temperature Controller. Okolab Objective Heater Features: Temperature controlled rubber band Easy to place around the ob…

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T Glass Plate

Okolab

The T Glass Plate - Round Transparent and flat surface at controlled temperature for Inverted Microscopes The T Glass Plate fits into the microscope XY stages with circular opening and provides a transparent and flat surface at controlled temperature. The combined action of the conductive glass with built in temperature sensor and of the state-of-the-art PID controller with 3.2’’ touch screen and advanced calibration routine e…

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T Glass Table

Okolab

T Glass Table provides a transparent and flat surface at controlled temperature. It can be placed in the optical path of any stereo microscope to provide a large, flat, clear, warm surface where several specimens can be maintained at physiological temperature. The combined action of the conductive glass with built in temperature sensor and of the state-of-the-art PID controller with 3.2’’ touch screen and advanced calibration…

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Metal T Plate

Okolab

Metal T Plate is a one-button solution for temperature control. Ideal to warm up the specimen during experiments lasting from minutes to hours where humidity and CO2 control are not required. It fits into the microscope stages with 110x160 mm opening. The combined action of the metal plate with built in temperature sensor and of the state-of-the-art PID controller with 3.2’’ touch screen and advanced calibration routine ensure…

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Microlab® NIMBUS NGS workstation

Hamilton Company

Hamilton’s Microlab® NIMBUS NGS workstation provides a completely automated and affordable solution for emPCR emulsion breaking, enrichment and sequencing primer hybridization for the Roche GS Junior System. The fully tested and validated NIMBUS NGS workstation features an integrated REM e system and provides convenient walk-away automation solution to minimize laborious manual process and reduce human errors. The automation p…

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iCell Cardiomyocytes

Cellular Dynamics International

iCell® Cardiomyocytes, human induced pluripotent stem (iPS) cell-derived cardiomyocytes, aid drug discovery and improve the predictability of drug efficacy and toxicity screens, weeding out ineffective and potentially toxic compounds early in the pharmaceutical pipeline process before significant time and resources have been invested. iCell Cardiomyocytes are a mixture of spontaneously electrically active atrial, nodal, and ve…

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