ChIP-exo High Resolution ChIP Assay
Active MotifAn optimized and streamlined protocol for high-resolution genome-wide mapping of transcription factor binding sites in the human and mouse genomes
Drug discovery > Basic Research Products & Reviews
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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.
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ChIP-IT® FFPE Kit
Active MotifProviding the highest quality ChIP-enriched DNA for analysis by qPCR or Next Generation sequencing
ChIP-IT® PBMC Kit
Active MotifSpecially formulated to perform ChIP from PBMCs, including lymphocytes (T cells, B cells and NK cells), monocytes and dendritic cells
enChIP
Active MotifModified ChIP assay that utilizes the CRISPR/Cas9 system to target a specific DNA locus for immunoprecipitation
DNMT Activity / Inhibition Assay
Active MotifHighly sensitive and rapid microplate-based assay to simplify the measurement of DNA methyltransferase activity
Global 5-hmC Quantification Kit
Active MotifELISA-based assay designed to detect and quantify 5-hydroxymethylcytosine (5-hmC) levels in genomic DNA from different sample types
Histone H3 PTM Multiplex Assay
Active MotifMultiplex epigenetic assay for high throughput profiling of histone post-translational modifications
Total Histone H3 ELISA
Active MotifSimple, sensitive method for detecting changes in histone methylation levels from purified core histones or histones isolated by acid extraction
Hydroxymethyl Collector™
Active MotifDetect and capture DNA fragments containing 5-hydroxymethylcytosine (5-hmC) DNA methylation for analysis
hMeDIP Kit
Active MotifImmunoprecipitate and enrich for DNA fragments containing 5-hydroxymethylcytosine (5-hmC)
MeDIP Kit
Active MotifImmunoprecipitate and enrich for single-stranded DNA fragments containing 5-methylcytosine (5-mC)
MethylCollector™ Ultra
Active MotifFast magnetic assay capable of efficiently isolating methylated CpG islands from fragmented genomic DNA
HypoMethylCollector™
Active MotifNovel technology that allows for positive identification of unmethylated DNA fragments
LightSwitch™ Luciferase Assay Kit
Active MotifReagents to measure luciferase reporter signal as part of the LightSwitch Luciferase Assay System
ChIP Antibody Validation Services
Active MotifSend us your antibody and let our ChIP Experts™ perform validation of your antibody for ChIP applications
Targeted Next-Generation Bisulfite Sequencing Service
Active MotifSingle base-pair, high-throughput solution for analysis of methylated DNA regions
MeDIP-Sequencing (MeDIP-Seq) Service
Active MotifComprehensive services for DNA enrichment and profiling of genomic regions marked by DNA methylation or DNA methyl variants
MethylCollector™ Ultra-Seq (MIRA-Seq) Service
Active MotifFastest, most efficient methylated DNA enrichment method on the market
hMeDIP-Sequencing (hMeDIP-Seq) Service
Active MotifComprehensive services for DNA enrichment and profiling of genomic regions marked by DNA methylation or DNA methyl variants
LightSwitch™ Custom Cloning Services
Active MotifCustom cloning services to clone any fragment from the human, mouse or rat genome into any LightSwitch luciferase reporter vector
LightSwitch™ Custom Mutagenesis Services
Active MotifCustom site-directed mutagenesis services to create any sequence variant from any existing LightSwitch reporter vector
LightSwitch™ Pathway Screening Services
Active MotifCell-based screening service to measure the effects of compounds on a variety of biological pathways