Drug discovery > Basic Research Products & Reviews

Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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AAV5 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of virions and assembled empty capsids of human Adeno-associated Virus 5. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins. The ADK5a antibody is used as capture and detection antibody in the AAV5 Titration ELISA (PRAAV5). Academic discount available on request.

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AAV9 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of intact AAV9 wt virions, AAV9 recombinant virions or assembled and intact empty capsids of human Adeno-associated Virus 9. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins. The ADK9 antibody is used as capture and detection antibody in the AAV9 Titration ELISA (PRAAV9). Academic discount available on request.

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Phage Titration ELISA

PROGEN

Kit allows fast titration of M13 particles by immunological recognition of protein VIII. Contains standard M13 titrated by electron microscopical method.

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AAV1 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of virions and assembled empty capsids of human Adeno-associated Virus 1. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins.

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AAV6 Titration ELISA

PROGEN

Unique microtiter plate enzyme immunoassay for the quantitation of intact AAV6 wt virions, AAV6 recombinant virions or assembled and intact empty capsids of human Adeno-associated Virus 6. The capture-antibody detects a conformational epitope not present on unassembled capsid proteins.  

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Baculo Expression Vector pAc-kappa-Fc

PROGEN

Baculovirus cassette vector pAc-kappa-Fc for the expression of human, humanized or chimeric IgG(kappa) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain Fab antibody gene fragments.

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Baculo Expression Vector pAc-lambda-CH3

PROGEN

Baculovirus cassette vector pAc-lambda-CH3 for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain scFv antibody gene fragments.

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Baculo Expression Vector pAc-lambda-Fc

PROGEN

Baculovirus cassette vector pAc-lambda-Fc for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain Fab antibody gene fragments.

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Human IgG / IgM Library Primer Set

PROGEN

PCR oligonucleotide primer sets consisting of 16  primers  for amplification and 16 primers  for cloning of human IgG and IgM heavy and light chain variable domain coding regions for generating universal, patient or antibody-specific scFv phage-display libraries. 

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