Drug discovery > Lead Discovery Products & Reviews

The Opto IM-compact M is characterized by the 90° angled all-aluminum housing with a width of only 40mm.  They can be equipped with different optics and camera technology and thus function as: USB/GigE reflected-light microscopes for opaque samples Quality assurance vision sensors with coaxial and ring light illumination Inverted digital microscopes with minimal height thanks to the angled design Plug & Play machine vision mi…

Model 1575 Immunowash Microplate Washer

Corning® Thermowell™ 96 well polycarbonate PCR microplates fit the most commonly used thermal cyclers For oil-free operation, plates must be used with sealing tape or a sealing mat and used in conjunction with thermal cyclers that have heated lids

The ideal device to accurately set and maintain temperatures.

Black microplates have low background fluorescence and minimize light scattering Designed to reduce well-to-well crosstalk High binding surface is capable of binding medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions Binding capacity is approximately 400 to 500ng IgG/cm2 Ideal for immunoassays Without lids, lids supplied separately Total volume is 360 µL; recommended working volu…

V-bottom wells with 320 µL total volume Recommended working volumes of 75 to 200 µL Nonreversable lids with condensation rings to reduce contamination Treated for optimal cell attachment Sterilized by gamma radiation and certified nonpyrogenic Individual alphanumeric codes for well identification Individually wrapped

Effective adhesive seal prevents evaporation during reaction and storage Can be removed from plate without leaving any residue Autoclavable (121°C, 20 min.) Certified free of human DNA, DNase, RNase and PCR Inhibitor*1 PCR Film, adhesive Sample can be visually monitored through the transparent film PCR Foil, adhesive Easy to pierce Pipette tip does not become tacky (ideal for automated systems) *1 Certifi…

Resistant to many common organic solvents (e.g., DMSO, ethanol, methanol) DNase- and RNase-free Total well volume 95 µL

Visible Spectrophotometer ideal for quality control in analytical or industrial laboratories where a high specification instrument and a wide choice of accessories are required. Features Basic routines (Absorbance, %Transmission, Concentration & Ratio) plus scanning, kinetics and standard curve capabilities Store methods Automatic system calibration Customize both the start-up menu and the accessible methods Lamp s…

The new Finnigan Pocket Surveyor software providing local instrument control for new and existing Finnigan Surveyor HPLC Systems. The software operates on a handheld computer running the popular Windows Pocket PC 2002 O/S and offers chromatographers the ability to connect directly to their Surveyor quaternary gradient pump and/or variable wavelength detector.   In addition to individual module control, the Finnigan Pocket Sur…

SEQUEST Cluster is a complete, preconfigured proteomics solution that enables accelerated throughput of increasingly complex, multidimensional informatics.Product detail:The SEQUEST Cluster offers a scalable solution for computing the large volumes of data typical in most proteomics analyses using LC/MS. Protein database search times are dramatically reduced by harnessing the power of several processing units in one, increasin…

DeNovoX software automates and accelerates sequencing, returning results equal to or better than those formerly achieved through expert manual sequencing of peptides within proteins and is ideally suited for high-throughput analyses of peptide mixtures. Product detail: DeNovoX is a fully-automated de novo sequencing software program that is capable of determining complete or partial amino acid sequences of unknown peptide…

LCquan 2.0 enabling 21 CRF Part 11 compliance. LCQUAN 2.0 is a closed, secure, multi-level user environment for mass spectral quantitative analysis. When LC Quan 2.0 is used in conjunction with Thermo's electronic Record Manager (eRM), this powerful combination provides the user with a completely secure data archival solution. Product detail: LCQUAN 2.0: Quantitation for the regulated laboratories Companies in regulated i…

Do you need interesting and unique building blocks for you small molecule combinatorial program? If you look at our 3500 In-House designed and externally acquired building blocks (from contract chemists) we are sure you will agree that this is a unique collection. These building blocks cannot be found in the major catalogues.

Are you looking for an immediate boost to your compound collection? If so, then ASINEX's Pre-Formatted libraries (9000 & 14240 small molecule compounds) could be what you are looking for. We can also create a library on request according to the specific parameters that you are interested in.Designed to represent maximum diversity and drug-likeness, our entire compound collection is available in a mini-format. If you have no ne…

Reversible Flip Seal—Same Cost, Twice the Lifetime New reversible Flip Seal inlet seals from Restek last twice as long as other inlet seals. Simply use—flip—then use again. The reversible design doubles the number of analyses you get per seal. •Same easy sealing as Dual Vespel® Ring Inlet Seals—no extra washer needed. •Lower leak rate than OEM metal seals. •Maximum transfer of analytes to column, due to highly inert gold or Si…

Software Platform for the Characterization of Polyolefins.

High Temperature Gel Permeation Chromatograph for Polyolefin Analysis.

Acclaim™ Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. his new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily opti…

The Thermo Scientific Acclaim™ Explosives E1 (5 µm) and E2 (5, 3 and 2.2 μm) silica-based reversed-phase columns are designed to resolve all 14 explosives listed in EPA SW-846 Method 8330: Nitroaromatics and Nitramines by HPLC. Their unique chemistries deliver superior resolution with complementary selectivities. The E1 is recommended for use as a direct replacement for ODS columns for the primary analysis.The E2 may be used a…

High-Resolution Separation of Proteins and Peptides The Acclaim® 300 features 3 µm silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residua…

The DNASwift™ SAX-1S is a strong anion-exchange column that provides exceptionally high resolution for the purification of oligonucleotides.The exceptionally high resolution provides superior purity and yields compared to other ion-exchange or reversed-phase columns available. The DNASwift column is ideal for therapeutic and diagnostic research, which have very high purity and yield oligonucleotides purification requirements.T…

The Thermo Scientific Acclaim™ PepMap™ 100 C18 column sets the benchmark in peptide separation.The PepMap100 C18 column is available in 3 or 5 µm particle sizes, with 100 Å pore sizes, and in nano, capillary, and micro formats. nanoViper fingertight fittings allow for easy column installation.Column Details: Chemistry: C18 Particle Size: 3, 5 μm Pore Size: 100 Å Length: 5, 15, 25, 50 mm ID: 75, 300 μm, 1.0 mm

Acclaim™ PepMap300 C18 is used for the separation of larger peptides and proteins.It is available in 5 µm particle sizes, with 300 Å pore sizes, and in nano, capillary, and micro formats.Column Details: Chemistry: C18 Particle Size: 3, 5 μm Pore Size: 100, 300 Å Length: 5, 15 mm ID: 75, 300 μm, 1 mm

MAbPac™ SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with…