Drug discovery > Lead Discovery Products & Reviews

Multi-chip Liver-12 consumable plates from CN Bio enable the advanced culture of 12 human 3D liver microtissues under perfusion/plate. Each microtissue recapitulates the functionality and microarchitecture of the human liver to accurately predict drug responses.

Multi-chip Barrier (MPS-T12) consumable Plates from CN Bio are used to culture advanced in vitro barrier models under perfusion, such as gut-on-a-chip or lung-on-a-chip, to predict human drug responses more accurately.

Multi-chip Dual-organ (MPS-TL6) consumable plates from CN Bio are used to culture interconnected 3D in vitro multi-organ-on-chip models under perfusion, such as Gut/Liver, or Lung/Liver, to generate clinically translatable data.

Multi-chip Liver-48 consumable plates from CN Bio enable the advanced culture of 48 miniaturized in vitro 3D liver microtissues under perfusion/ plate for comparative drug screens. Each microtissue recapitulates the functionality and microarchitecture of the human liver to accurately predict drug responses.

Alturas Analytics is a CRO specializing in preclinical and clinical bioanalysis

We have earned a reputation as innovative problem solvers, with a successful history of addressing the challenges of working with biomolecules, prodrug instability, and multi-analyte assays.

The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health. The assay uses a two-step, addition-only process to make these measurements in a single well of a plate, negating the need to run parallel assays. The first part of the assay is a nonlytic fluorescence assay (CellTiter-Fluor™ Cell Viability Assay) that measure…

QuantiFluor® ONE system maximizes sensitivity and efficiency for dsDNA quantitation.   The QuantiFluor® ONE dsDNA System contains a fluorescent double-stranded DNA-binding dye (504nmEx/531nmEm) developed for use in an “add-and-read” format for dye and standard, making sample quantitation easy. This system enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA). The QuantiFluor® ONE dsDNA Sy…

The Maxwell® Clinical Sample Concentrator (CSC) automated nucleic acid extraction system is designed for clinical laboratories needing to process multiple samples for critical downstream assays. This easy-to-use, cGMP-compliant system provides consistent, high-quality results with every run, allowing you to manage your workflow and gain efficiency. The purification methods use sample lysis and binding to paramagnetic par…

The QuantiFluor® ONE dsDNA Dye is a fluorescent double-stranded DNA-binding dye (504nmEx/531nmEm) prepared for an “add-and-read” format making sample quantitation easy. This dye enables sensitive quantitation of small amounts of double-stranded DNA (dsDNA).   The QuantiFluor® ONE dsDNA Dye is intended for use as a general purpose reagent in the US and is suitable for use by clinical laboratories as a component of la…

New line of standard and low-profile PCR plates for improved PCR efficiency.   Improve PCR efficiency with a new line of PCR plates manufactured with the best raw materials using the latest in production technologies. Standard and low profile PCR plates in clear and white are suitable for use in most thermal cyclers. These new plates combine extra-thin and uniform wall thickness with a rigid upper PP deck for easy handli…

All BRAND PCR products are available in white plastic, uniformly colored with titanium dioxide (TiO2) for optimal results when performing quantitative PCR (gPCR) with fluorescent signals.   BRAND microcentrifuge tubes fit most common rotors and may be spun up to 20,000 RCF (10,000 RCF for 0.5mL). Manufactured from virgin polypropylene, these highly translucent tubes are free from flash, air bubbles, and streaks. Caps are…

BRANDplates® inertGrade™ 96-well plates are especially suited for cell culture applications when adhesion is not desired. These plates are specifically designed for the cultivation of suspension, tumor, and stem cells, as well as other spheroid or 3-dimensional tissue culture models. They feature a surface that reduces cell adhesion and protein absorption to minimize enzyme and cellular activation. All BRANDplates® inertGra…

BRAND UV-Cuvettes are a popular disposable alternative to quartz spectrophotometry cuvettes. They are excellent for DNA, RNA, and protein analyses as well as many other applications between 230-900nm. BRAND UV-Cuvettes are a more convenient and economical choice than quartz cuvettes. They eliminate the risk of cross-contamination from reuse and the need for cuvette washing. The proprietary material offers chemical compatibi…

Innovative cell culture plates and inserts for co-culture, migration/invasion assays, 3D tissue preparation and more.   The BRANDplates Insert System, co-developed with the Fraunhofer Society, offers an innovative expansion of the BRAND cell culture product line. The new Insert system consists of 24-well standard and 6-well specialized plates and strips of hanging cell culture inserts for applications such as co-culture,…

Adaptable Microplate Solution for Custom ELISA Applications. BRANDplates® Strip Plates are especially suited for laboratories designing custom ELISA applications, or desiring increased flexibility in their ELISA application. To ensure the effective binding of a wide range of antigens or antibodies to the microplate surface, the strip plates are available in two treatment types: pureGrade™ or immunoGrade™. The pureGrade™ plate…

The BRAND Liquid Handling Station pipetting robot handles routine tasks at high speed and with the highest precision. The LHS closes the gap between electronic pipettes and highly complex, expensive pipetting robots. It is a quiet and compact instrument with a unique front door allowing it be set up in tight quarters. The instrument has 7 working positions and 5 available liquid ends with single channel volumes up to 1000uL an…

Sensitive Quantitation of Single-Stranded DNARequires less DNA than spectrophotometry

The BRAND Liquid Handling Station (LHS) pipetting robot handles routine tasks at high speed and with the highest precision.

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

BRAND 96, 384, 1536-well polystyrene and polypropylene microtitration plates are excellent for cell and tissue culture, sample storage, immunological assays, and other applications. BrandTech Plates have 96, 384 and 1536 wells and are available with 330µL or 400µL well volumes. They are fully compatible with most standard plate readers and washers. Both sterile and non-sterile BRAND plates are available with rounded, V-shaped…

The QuEChERS Clean-up step is rapidly completed using the QuICK QuEChERS cartridge. This self-contained cartridge contains 110 mg of anhydrous MgSO4 and 180 mg of PSA. Placed on the end of a disposable syringe, the QuEChERS extract is pushed through directly into a sample vial for analysis. Clean-up is equivalent to dSPE clean-up, but faster and easier, eliminating the need for centrifugation.

Activated carbon cartridge product EU52112M6 with 2 grams carbon/6 mL cartridge has proven to be effective for the extraction of nitrosamines in drinking water Method 521.  EPA Method 522 for 1, 4 dioxane is extracted using one of two options.  EU52112M6 is suitable for Option 1 which uses this product with 2 grams carbon in a 6 mL cartridge.