Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…
The Andor Shamrock SR-500i imaging platform is the latest addition of the Andor family of spectrographs based on Czerny-Turner optical design. The optimized optical design provides exceptional performance for multi-track Spectroscopy.The Shamrock 500i is available as a pre-aligned, pre-calibrated camera/spectrometer detection solution allowing for seamless integration in user set-up. The Spectroscopy-dedicated software interfa…
G-Protein Coupled Receptors (GPCRs) are common drug targets. Previously, most studies were based on the monomeric model, but this perception of GPCRs is now evolving towards homodimeric , heterodimeric and oligomeric models. To facilitate research into GPCR dimers, CisBio Bioassays has applied the Tag-lite® technology to GPCR interaction assays. Based on HTRF® technology, plasmids have been designed to express either the SNA…
Cisbio Bioassays offer a comprehensive cellular platform to develop HTRF® ligand binding assays.Features: • Single technology and cellular platform for all GPCR assays • Unique non-radioactive ligand binding assays • Miniaturization down to < 10µl • Peptidic and non-peptidic fluorescent ligands • High Specific Binding • Low Non-Specific Binding with HTRF technology Tag-lite fluorescent ligands available for (Feb10): Vasopre…
Tag-lite® cell-lines and reagents, a multimodal environment streamlined for GPCR studies. Cellular trans-membrane receptors are high potential therapeutic targets in pharmacological research, among them G-Protein Coupled Receptors (GPCRs). To reach a better physiological understanding, their study is deepening and is now focusing on structural assessments (ligand binding, dimerisation) and also on multiple signal pathway assa…
The EXPRESS-Pick small molecule screening compound stock is a collection of 460,000 druglike, small molecule compounds, available for custom selection.
Structurally diverse small molecule libraries with broad 3D pharmacophore coverage for hit identification ChemBridge offers two, complementary DIVERSet™ Libraries, each composed of 50,000 leadlike and druglike compounds. Both DIVERSet Libraries (the DIVERSet-EXP and the DIVERSet-CL) are designed to provide the greatest coverage of pharmacophore space within 50,000 compounds while maintaining chemical structure diversity. Th…
CNS-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
Pre-plated selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
Ion channel-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
GPCR-targeted compounds based on beta-turn mimetic scaffolds designed by ChemBridge.
Kinase-directed selection from ChemBridge's EXPRESS-Pick Collection screening compound stock.
Kinase-directed selection from ChemBridge's CORE Library screening compound stock.
Roche NimbleGen provides a unique combination of high-density arrays, long-oligo probes, and flexible design capability that together provide superior results for advanced gene expression analysis. NimbleGen microarrays enable accurate, sensitive, and specific interrogation of genome-wide expression for any sequenced and annotated genome. Researchers also can tile through a genome at any desired spacing to discover genome-wide…
Agilent’s contract Lead Discovery Service utilizes label-free RapidFire technology for direct quantitation of a wide range of native analytes across diverse therapeutic areas. Supports SAR programs via retesting of hits. Uses your existing assays or RapidFire custom-developed assays. Quick data turnaround for faster drug discovery decisions.Screened as singletons or compressed format The ideal candidate assays are often the sa…
The universal grinder for every application
The most precise way of sample division
Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) DNase- and RNase-free Total volume is 360 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately
The introduction of NGS technologies into the market has changed the way we think about scientific approaches in basic, translational and clinical research. The development of NGS applications is a rapidly evolving field – making for exciting times in genomic studies. The ability to produce large numbers of readouts at low cost makes NGS platforms useful for many applications. Next-generation sequencing applications include:•…
Bruker BioSpin launches a breakthrough one Gigahertz Ultra-High Field AVANCE 1000 MHz NMR spectrometer. Incorporating a record-breaking 23.5 Tesla standard-bore (54 mm) superconducting NMR magnet, the AVANCE 1000 MHz NMR spectrometer, brings one Gigahertz technology to NMR research. AVANCE 1000 MHz NMR Spectrometer with the first 1 GHz CryoProbe installedThe high field strength and high field stability in combination with the…
CYTOOplates are optical grade, glass-bottom microplates in 96 or 384-well format with black-side upper structures for fluorescence applications offering reduced background and minimum scattered light. Each well holds an array of over 4,000 (96-well) or 1,000 (384-well) identical micropatterns. CYTOOplates are compatible with your High Content Screening equipment.
The CYTOOchamber™ is a 35mm footprint device specially designed and manufactured for the 2x2cm² square CYTOOchip™ format which enables you to do high resolution timelapse microscopy. The CYTOOchamber uses a patented magnetic system for easy assembly. The CYTOOchamber has the same footprint as standard 35mm culture dishes and therefore will fit into all 35mm microscope stage adaptors. Components: • 1 bottom plate • 1 upper mai…
SCOPE OF APPLICATION ASEPTIC FILLING • Pharmaceutical • Diagnostic • Biopharmaceutical • Disposable filling • Aseptic liquid filling • Peristaltic liquid filling • No cleaning validation • Easy product change-over • Ideal for small batch production • No cross contamination • High accuracy filling VERY COMPACT Machine dimensions are 1.13 x 2.05 m, i.e. FMB210 takes up very little space in a cleanroom. SHORT CHANGE OVER TIME Ide…
The MS-3 laser scanner offers the fastest read performance in embedded compact bar code scanners. The wide scan angle of 70 degrees is coupled with ultra-compact size and flexible mounting. • Decodes/second: up to 1000 • Read Range: 2 to 10” (51 to 254 mm) • Wide Scan Angle • IP54 Enclosure High performance and flexibility make the MS-3 the optimal choice for reliable reading in embedded instruments. Compact & Lightweight: The…
