Drug discovery > Lead Discovery Products & Reviews

Compounds are retained on hydrophilic sorbents through polar interactions including hydrogen bonding, pi-pi or dipole-dipole interaction.  Compounds typically extracted on a hydrophilic column include analytes which have polar groups, including amines, hydroxyls and carbonyls. Elution is performed by strong polar solvents. For these types of extractions UCT offers various types of base silica, Florisil®, Alumina's, cyanopropy…

This sorbent is composed of a silica backbone bonded with a carbon chain terminated by a negatively or positively charged functional group. Ion exchange interactions occur between a sorbent that carries a charge and a compound of opposite charge. This electrostatic interaction is reversible by neutralizing the sorbent and /or analyte. Ion exchange bonds can also be disrupted by introduction of a “counter ion” to compete with…

This sorbent is composed of a silica backbone bonded with a carbon chain terminated by a negatively or positively charged functional group. Ion exchange interactions occur between a sorbent that carries a charge and a compound of opposite charge. This electrostatic interaction is reversible by neutralizing the sorbent and /or analyte. Ion exchange bonds can also be disrupted by introduction of a “counter ion” to compete with…

The same clean polypropylene tubes we use in our own column assemblies are available as an empty tube. Available in 1mL through 150mL tube sizes. The flange on the lip means the columns are suitable for use with UCT's positive pressure manifold as well as with vacuum manifold systems.

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.

Stainless Steel Manifold -available in single, 3 and 6 station designs. The 3 and 6 multi-station manifolds allow the simultaneous processing of multiple samples.

CLEAN SCREEN FASt THC is the newest sorbent in our FASt product lineup. It employs a process that uses positive pressure and a solid phase sorbent bed built with small pore frits to quickly and efficiently prepare urine samples for LC/MS analysis. This method eliminates timely centrifugation, reduces matrix suppression effects, and removes particulates greater than ~1μm. Samples can be diluted at a ratio as low as 1:1, which i…

The CLEAN SCREEN® THC column is copolymerized on a rigid, purified silica gel support. The two functional groups include a reverse phase, and an ion exchanger, primary amine. This column is commonly used for analyzing THC and its metabolites. It has dual functionality for acids and hydrophobic compounds.

Clean Screen® GHB is a patented mixed-mode column designed for the filtration extraction of ethylene glycol, butan diol, gamma hydroxy butyrate and butyrolactone.

Clean Screen® ETG is a proprietary carbon blend column designed for the extraction of ethyl-glucuronide from urine.  Extracts are suitable for either GC/MS or LC/MS analysis.