Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
Human phosphodiesterase 2A and a contitutively active Gs-coupled GPCR are stably expressed in HEK293-CNG (GPCR & Cyclic Nucleotide-Gated channel) cells. (HEK293-CNG-Gs). Cat#: CT81200-101. Cryopreserved cells, 2 vials: 2.5x10E6 cells/vial. Platform validation:
Endogenous phosphodiesterase 4 and a constitutively active Gs-coupled GPCR are stably expressed in GPCR-CNG (G protein-coupled receptor & Cyclic Nucleotide-Gated channel) cells. (HEK293-CNG-Gs). Cat#: CT81200-100. Cryopreserved cells, 2 vials: 2.5x10E6 cells/vial. Platform validation:
Enhanced selectivity for polar analytes: LiChroPLATE® EN microtiter plates for solid-phase extraction shortens sample preparation time up to 75% compared with other polymer phases. By using LiChroPLATE® EN in combination with an 8-channel pipettor, it is possible to extract 96 samples in less than half an hour. EN stands for enhanced selectivity with respect to all polar analytes – whether basic, neutral or acidic. Even for la…
Human MDR1 Transporter-expressing, stable replicating cell line (HEK293). Cat#: CT6202. Cryopreserved cells, 3 vials: 2x10E6 cells/vial. Platform validation: FLIPR®
Human MDR1 Transporter-expressing, transiently transfected cells (HEK293). Cat#: CT7202. Cryopreserved cells, 6x10E6 cells/vial. Platform validation: FLIPR®
Human 5HT1A Serotonin Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A601. Cryopreserved cells, 6 million cells per vial
Human A3 Adenosine Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A603. Cryopreserved cells, 6 million cells per vial
Human Alpha2B Adrenergic Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A604. Cryopreserved cells, 6 million cells per vial
Human Serotonin 5-HT6 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A605. Cryopreserved cells, 6 million cells per vial
Human Protease-Activated PAR1 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A608. Cryopreserved cells, 6 million cells per vial
Human Protease-Activated PAR4 Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A609. Cryopreserved cells, 6 million cells per vial
Human Chemokine CCR2B Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A610. Cryopreserved cells, 6 million cells per vial
Human CB1 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A617. Cryopreserved cells, 6 million cells per vial
Solid-phase extraction for increased productivity: LiChroPLATE® RP-18 microtiter plates for solid-phase extraction enable ultra-rapid sample preparation with excellent recovery rates and high precision. Up to 96 samples can be processed simultaneously, which means a significant reduction in the time needed for sample preparation and consequent savings on purchasing and disposal costs. The batch-to-batch reproducibility of LiCh…
Human CB2 Cannabinoid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A618. Cryopreserved cells, 6 million cells per vial
Human FPRL1-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A621. Cryopreserved cells, 6 million cells per vial
Human Edg-1 (S1P1) Lysophospholipid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A623. Cryopreserved cells, 6 million cells per vial
Human LPA1 Lysophosphatidic Acid Receptor-expressing GPCR (G protein-coupled receptor) stable, replicating cell line. (RH7777). Cat#: A624. Cryopreserved cells, 6 million cells per vial
Human LPA4 Lysophospholipid-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (HEK293). Cat#: A626. Cryopreserved cells, 6 million cells per vial
Human Thromboxane A2-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (HEK293). Cat#: A627. Cryopreserved cells, 6 million cells per vial
Human Angiotensin AT1-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A628. Cryopreserved cells, 6 million cells per vial
Human PKR2 Prokineticin-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A629. Cryopreserved cells, 6 million cells per vial
Human GPR119 Stable-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (CHO-K1). Cat#: A633. Cryopreserved cells, 6 million cells per vial
Human MrgX2 Stable-expressing GPCR (G protein-coupled receptor) stable, replicating cell line (HEK293). Cat#: A635. Cryopreserved cells, 6 million cells per vial
For direct in-line sample preparation of untreated bio-fluids: LC-integrated sample preparation with LiChrospher® ADS is less expensive, less time consuming and more precise in comparison to conventional off-line sample preparation. LiChrospher® ADS allows the direct extraction and enrichment of hydrophobic, low molecular analytes from untreated samples such as haemolysed blood, plasma, serum, milk, salivary fluid, fermentatio…
