ChemiScreen™ CALCIUM-OPTIMIZED STABLE CELL LINE HUMAN RECOMBINANT M2 MUSCARINIC ACETYLCHOLINE RECEPTOR
MerckChemicon's cloned human M2-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant M2 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between M2 and its ligands.