ChemiSCREEN™ Human Recombinant S1P1 Lysophospholipid Receptor Calcium-Optimized Stable Cell Line
MerckChemicon's cloned human S1P1-expressing cell line is made in the Chem-1 host, which supports high levels of recombinant S1P1 expression on the cell surface and contains high levels of the promiscuous G protein Gα15 to couple the receptor to the calcium signaling pathway. Thus, the cell line is an ideal tool for screening for antagonists of interactions between S1P1 and its ligands.