Drug discovery > Lead Discovery Products & Reviews

Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques

Product Filter

Drug discovery > Lead Discovery
Browse by Techniques
Explore by Company

Ratings

Search

SPME-LC Fiber Probe

Sigma-Aldrich Supelco

The SPME-LC fiber probes are intended as single-use devices for the extraction of small molecules out of a fluid followed by solvent desorption and LC analysis.Traditional solid phase microextraction (SPME) fibers were developed with common GC type phases, which were primarily designed for extraction of volatile or semi-volatile compounds using thermal desorption as the means of introducing sample into the chromatographic colu…

0.0/5.0
|0 Reviews

Carboxen®/Polydimethylsiloxane (CAR/PDMS) fibers

Sigma-Aldrich Supelco

Carboxen®/Polydimethylsiloxane (CAR/PDMS) SPME FibersSolid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of solid coatings. The…

0.0/5.0
|0 Reviews

Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS) fibers

Sigma-Aldrich Supelco

Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS) SPME FibersSolid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of sol…

0.0/5.0
|0 Reviews

Molded Thermogreen® LB-2 GC Septa

Sigma-Aldrich Supelco

The Perfect Combination of Low Bleed, Thermal Stability, and Easy Puncturability!Molded Thermogreen LB-2 septa are manufactured from high quality, low bleed material using the same exclusive LB-2 rubber formulation that chromatographers are accustomed to using. The difference is that molded septa, unlike traditional die-cut septa, offer easier installation and better sealing inside the injection port. This is because our liqui…

0.0/5.0
|0 Reviews

Derivatization Reagents for Silylation

Sigma-Aldrich Supelco

Supelco provides high quality derivatization reagents for silylation.Silylation is the most widely used derivatization technique. Functional groups that present a problem with gas chromatogaphy detection - hydroxyl, carboxylic acid, amine, thiol, phosphate - can be derivatized by silylation reagents. Silylation involves replacement of the acidic hydrogen with an alkylsilyl group, for example, -SiMe3.Silylation derivatives are…

0.0/5.0
|0 Reviews

Derivatization Reagents for Acylation

Sigma-Aldrich Supelco

Supelco provides high quality derivatization reagents for acylation.Acylation, an alternative to silylation, allows the conversion of compounds with active hydrogen such as -OH, -SH, and -NH into esters, thioesters and amines, respectively. A very popular example of this method is the insertion of perfluoracyl groups to enable electron capture detection (ECD). Carbonyl groups adjacent to halogenated carbons enhance the ECD res…

0.0/5.0
|0 Reviews

Derivatization Reagents for Alkylation & Esterification

Sigma-Aldrich Supelco

Supelco provides high quality derivatization reagents for akylation and esterification.Alkylation is the replacement of the active hydrogen in R-COOH, R-OH, R-SH, R-NH, R-NH2, R-CONH2, R-CONH-R′ with an alkyl group, or sometimes an aryl group.Esterification is the first choice for derivatization of carboxylic acids and other acidic functional groups. Acids are reactive compounds, and are too polar to be well separated by gas c…

0.0/5.0
|0 Reviews

Supel™Connect High Performance Fittings

Sigma-Aldrich Supelco

Supelco® has developed a line of high performance fittings that maintain the integrity of your HPLC systems up to 15,000 psi with mere finger tightening!The use of HPLC systems to achieve faster analyses and increased resolution pushes systems toward higher operating pressures. Our selection of Supel™-Connect High Performance Interconnects and Fittings will assist the chromatographer in maximizing system performance and reliab…

0.0/5.0
|0 Reviews

Custom Made Packed GC Columns

Sigma-Aldrich Supelco

Supelco’s complete line of stock and custom packed GC columns are configured to fit most commercially available GC instruments.Supelco® has been the leader in packed GC column technology for over 40 years. Should you not be able to locate a stock item to fit your needs, our custom capabilities allow us to manufacture columns and packings to your specifications. In addition we also carry hard-to-find tools specifically designed…

0.0/5.0
|0 Reviews

High Capacity Gas Purifier

Sigma-Aldrich Supelco

High Capacity Gas Purifiers (Remove Moisture and Oxygen)The best purifier choice for removing moisture and oxygen from carrier gas streams is our High Capacity Gas Purifier. It consists of three parts:• Clam-shell oven• Replaceable heating elements• Replaceable converter tube.A convenient starter kit contains all three items for new installations.

0.0/5.0
|0 Reviews