Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
The 1260 Infinity II Online Sample Manager is an online sampling module that connects the analytical world with the process world. The module provides automated sample analysis via direct injections or retained samples from flow reactors, batch reactors, as well as upstream bioreactors and downstream purification devices.
Bioinformatics and Protein Array Services
Profiling against cancer antigens. Using the CTA Protein Array, Sengenics can quantify autoantibodies against more than 200 clinically relevant cancer testis antigens. These are tumor antigens normally expressed in germ cells but not in adult somatic tissues. In cancers, this regulation can be disrupted, resulting in CTA expression in tumors. The CTA array is ideal for research related to cancer immunotherapy.
Cancer drug screening and discovery. The OncoRex p53 Cancer Array provides a biologically relevant screening tool since all p53 variants are correctly folded and functional using the patented KREX ® protein folding technology. Using the array, Sengenics can screen your therapeutic antibodies and protein binding compounds against more than 100 p53 wildtype and mutant variants by measuring their impact on DNA binding as a func…
The 1260 Infinity II Prime Bio LC System is a versatile HPLC for bioseparations and offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.
The 1290 Infinity II Bio High-Speed Pump is a binary UHPLC pump consisting of biocompatible material for use in biopharma and other applications utilizing high salt and extreme pH conditions. It uses high-pressure blending from up to two solvents at pressures up to 1300 bar and flow rates up to 5 mL/min.
The 1260 Infinity II Bio Flexible Pump is a UHPLC pump comprising biocompatible components, developed for biopharma applications and for other analyses requiring high-salt and extreme-pH conditions. This pump enables quaternary solvent delivery at pressures up to 800 bar and flow rates up to 5 mL/min.
The 1290 Infinity II Bio Multisampler, with its biocompatible sample flow path, is perfectly suited for biomolecule analysis, ensuring integrity of biomolecules and minimizing unwanted surface interaction. For temperature-sensitive samples, a compressor-based thermostatting device can be added.
