Life sciences encompass a diverse range of scientific disciplines focused on the study of living organisms and their interactions with the environment. From basic life sciences (such as cell biology, genetics, immunology, and microbiology) to applied life sciences (such as disease research, multi-omics, and biotechnology), this broad field explores the fundamental processes of life and drives advancements in disease research, patient care, and our overall understanding of living organisms. Discover the endless possibilities of life sciences and their impact on shaping a healthier and more sustainable world.
Fusion of proteins to Glutathione S-Transferase (GST) of Schistosoma japonicum is a common technique to increase solubility and expression level of a protein. Furthermore, GST-tagged fusion proteins are often used in protein-protein interaction studies. Both approaches require highly specific tools to isolate and detect GST fusion proteins. GST-Trap The GST-Trap is a highly specific and robust GST-binding protein coupled to ma…
DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…
Proliferating cell nuclear antigen (PCNA) is a homotrimeric ring-shaped protein that encircles DNA and acts as a loading platform for multiple, transiently interacting factors participating in various DNA transactions. PCNA plays a key role in DNA replication, repair, cell cycle regulation, and post-replicative transactions like DNA methylation and chromatin remodeling. All these cellular processes are regulated by a complex n…
Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…
RNA polymerase II features a large carboxyl-terminal repeat domain (CTD) that consists of the consensus heptapeptide Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Differential phosphorylation in this CTD orchestrates accessibility for various co-factors of the transcription complex. Using the phosphorylation specific antibodies it is now possible to determine specific phosphorylation states. In addition to phosphorylation specific antib…
The VisiTIRF Fluorescence Imaging System from Visitron Systems is the ideal solution for the analysis of finest structures or surfaces. The flexibility of the VisiTIRF system and the use of scientific digital CCD camera systems with optimal resolution, speed and sensitivity allows for the adaptation of customized application and configuration. For fluorescence illumination Visitron use solid state lasers or laser diodes . The…
The DH-40iL Microincubator is designed for imaging live cells under constant temperature and atmospheric conditions. This versatile incubation system enables high resolution image analysis, fluorescence microscopy, and time-lapse imaging studies while accommodating both upright and inverted microscopes. Designed to provide complete environment control for either the Series 40 open bath chambers or 35 mm cell culture dishes. E…
The Bold Line Top Stage Incubator H301 is the latest release from OKOLAB in terms of Top Stage incubation. It delivers superior temperature stability, humidity, CO2 and Oxygen control in a fully integrated fashion. The Bold Line Top Stage Incubator H301 Equipment: Incubating Chamber: fits in the microscope stage and holds the specimen. It is equipped with heated glass lid and Temperature and Humidity sensors. T Unit: Bo…
The Water Jacket Incubator provides superior incubation stability above and below room temperature. Water is pumped from a water bath into the base plate and into the lid, which are both Water Jackets. Temperature Control Mechanism Temperature is directly measured inside a reference Petri-dish and is controlled by circulating water from a water bath into the Water Jacket Chamber. The Temeprature Controller reads the temperatur…
UNO-PLUS All-in-one single specimen incubator with the size of a Multi Well plate. UNO-PLUS Features: All-in-one temperature/humidity/CO2 incubator Top Stage Incubator with the footprint of a Multi Well Plate Fits in any XY stage, with the additon of the Multi Well Plate holder (supplied by the stage manufacturer or by Okolab) Specimen holders for #1 35mm dish, #1 glass slide or #1 chambered coverglass Heated Glass Cov…
Inductively Coupled Plasma Mass Spectrometer (ICP-MS) The Science of sensitivity Bruker's ICP-MS is famous for its innovative and unique technology and has now been further refined to meet the ever increasing demands of latest application and laboratory requirements. Bruker's aurora M90 continues to be the workhorse for the routine laboratory, now with additional and improved characteristics. In addition to the aurora M90, Bru…
High-resolution STEM imaging The Model 3000 Annular Dark Field (ADF) Detector is ideal for high-resolution scanning transmission electron microscopy (STEM) imaging. It allows simultaneous high angle ADF imaging and electron energy less spectroscopy (EELS). It has single electron detection capabilities and high quantum efficiency. The detector is pneumatically retractable from the beam path. Atomic-resolution imaging and Z-cont…
Provides clean environment for SEM The Cryo-Can provides a clean environment for SEM sample imaging and analysis. It helps eliminate chamber contamination resulting from sample outgassing and other sources. The Cryo-Can improves both imaging and analytical data quality. It is ideal for high beam current applications. Uses SEM vacuum system The Cryo-Can vacuum container is readily connected to one of the SEM chamber ports and d…
Revolutionary ultra-low-energy, concentrated ion beam Fischione’s Model 1040 NanoMill® TEM specimen preparation system is an excellent tool for creating the high-quality thin specimens needed for advanced transmission electron microscopy (TEM) imaging and analysis. It is ideal for both post-FIB (focused ion beam) processing and the enhancement of conventionally prepared specimens. Targeted, ultra-low-energy NanoMillingsm proce…
High-quality thin foils for TEM Electrolytic thinning of conductive materials is an effective method of quickly producing specimens for transmission electron microscopy (TEM) without any induced artifacts. In the Model 110 Twin-Jet Electropolisher, twin jets simultaneously polish both sides of the sample, creating electron transparent specimens within a few minutes. The Electropolisher features easily adjustable electrolyte fl…
AZtecEnergy will change the way you collect, process and view EDS data. Whether novice or expect, you’ll gather more accurate results, see everything in stunning high resolution, and finish the job faster than ever. Building on over 40 years experience and the feedback from the world’s largest microanalysis user community, AZtec is everything you’d expect of an Oxford Instruments system. Only better.
Disposable cuvettes for spectrophotometry, optical PS visible range cuvettes, UV Grade PMMA cuvettes. Standard and semi-micro disposable cuvettes for spectroscopy made of optical PS and PMMA UV grade optical windows to achieve optimal transmittance through spectral range from 340 to 800 nm (OPS) an from 280 to 800 nm (PMMA UV qrade). The engineering and quality control determine the reproducibility of the cuvettes. These are s…
The PELCO® STEM imaging holder enables STEM imaging in the SEM by using the standard Everhart-Thornley SE detector in the SEM chamber. The standard 3mm TEM grid is placed in the grid holder and located under the scanning beam. The STEM image is created by the adjustable Pt conversion plate which must face the chamber SE-detector. Cost-effective method for STEM imaging by using the existing SE detector in the SEM chamber. The i…
Thermo Scientific QuasOr, the no compromise EBSD. Electron Backscatter Diffraction (EBSD) enables nanostructural analysis in the electron microscope by characterizing the crystalline structures which affect physical properties in a wide range of materials. As an integral part of the Thermo Scientific NORAN System 7, simultaneous acquisition of EBSD and EDS/WDS spectral images are performed with ease.
The SureSelect Strand-Specific RNA Library Preparation kit prepares Poly(A) enriched libraries for whole-transcriptome sequencing. Sequence a wide range of RNA to detect gene expression changes and alternative splicing. The kit contains mRNA sequencing library preparation and enrichment materials.
Genomic DNA ScreenTape analysis provides fast, automated and reliable electrophoretic separation of input genomic DNA samples. The gDNA ScreenTape assay can separate DNA samples from 200 to more than 60,000 base pairs in less than 2 minutes/sample. Samples can be analyzed from multiple sources including FFPE.
The VenaT4™ biochip model combines Cellix's proprietary microfluidic flow technology for cell recruitment under shear stress with traditional transwell chamber models. Used to investigate and quantify cell recruitment to various ligands in the presence of chemoattractants contained within the microwells mimicking tissue and / or injury sites. The biochips contain 4 microcapillaries in parallel, each with an embedded microporo…
The FlowCellect™ Human NK Cell Characterization Kit includes three directly conjugated antibodies, Anti-CD3-APC, Anti-CD56-PE, and Anti-CD16 FITC. This three color kit is designed to characterize NK within mixed cell populations. The antibodies provided have been carefully titrated to ensure the ability to accurately measure the expression of all markers simultaneously. Sufficient reagents are provided to perform 25 three-colo…
The praying mantis diffuse reflectance accessory is useful for measuring the diffuse reflectance of low volumes of powders and pastes. Using two large hemispherical mirrors, it collects the light reflected from the crystalline sample, enabling the full wavelength range of the Cary instrument to be used. The accessory can be used with the Cary 4000, 5000, 6000i, and 7000 instruments.
Bruker’s innovative PIONA+™ Analyzer, based on the powerful 450-GC gas chromatograph, provides a highly flexible platform to obtain comprehensive characterization and quantitative information, including hydrocarbon group types, aromatics and oxygenates per carbon number for spark emission fuels. The system comes complete with ultra high performance columns and traps, CompassCDS™ chromatography data handling software and PIONA+…
