Drug discovery > Pre-Clinical Development Products & Reviews

The SamplePLUS is a 100% synthetic sample buffer for dilution of human or veterinary serum or plasma samples.The buffer efficiently minimizes cross-reactions, background and unspecific binding without inhibiting the specific binding.

The Sample Tracer is a 100% synthetic sample buffer for dilution of human or veterinary serum or plasma samples. The buffer efficiently minimizes cross-reactions, background and unspecific binding without inhibiting the specific binding. The Sample Tracer™ appears red, and when serum or plasma is added the Sample Tracer™ change colour to yellow. The buffer can detect serum or plasma in dilutions up to 1:100. If the advantage…

OPD, Ortho-Phenylenediamine, is used as a chromogen substrate in ELISA procedures with an absorption maximum at 492 nm and produces a yellow colour during the enzymatic degradation of hydrogen peroxide by horseradish peroxidase. After addition of sulfuric acid you will obtain a very stable end solution. The fizzing, buffer containing tablets are dissolved in distilled water within few minutes. This will give solution of pH 5.2…

OPD, Ortho-Phenylenediamine, is used as a chromogen substrate in ELISA procedures with an absorption maximum at 492 nm and produces a yellow colour during the enzymatic degradation of hydrogen peroxide by horseradish peroxidase. After addition of sulfuric acid you will obtain a very stable end solution. The fizzing, buffer containing tablets are dissolved in distilled water within few minutes. This will give solution of pH 5.2…

OPD is used as a chromogen substrate in ELISA procedures with an absorption maximum at 492 nm and produces a yellow colour during the enzymatic degradation of hydrogen peroxide by horseradish peroxidase. After addition of sulfuric acid you will obtain a very stable end solution. Stability life time is 18 months at 4°C. Our standard tablets are available with a content of 2 mg or 10 mg OPD.

AEC (3-amino-9-ethylcarbazole) is used as a chromogen substrate in immunoblotting and immunohistochemistry. AEC produces a rose-red colour during the enzymatic degradation of H2SO4 by horseradish peroxidase. Each tablet contains 5 mg of AEC and dissolves in approx. 5 minutes. 1 tablet is added 1 ml of 96 % alcohol, followed by addition of distilled water to 10 ml. This will give a solution of pH 5.1 + 0.1 buffered with 20 m…

DAB (3,3-diaminobenzidine tetrahydrochloride), is used as a chromogen substrate in immunoblotting.DAB produces a brown colour during the enzymatic degradation of H2SO4 by horseradish peroxidase. Each tablet contains 10 mg of DAB and dissolves in distilled water in less than 5 minutes. Stability life time is 18 months at 4°C.

Fast Red is used as a chromogen substrate in immunoblotting and immunohistochemistry using alkaline phosphatase antibody conjugates. Each tablet contains 0.5 mg naphthol phosphate, 2 mg FAST RED chromogen and 0.4 mg levamisole, an inhibitor of endogenous enzyme activity. Stability life time is 18 months at 4°C.

The pNPP (p-NitroPhenyl Phosphate) liquid, ready-to-use substrate is a highly active and stable formulation utilized for measuring AP- (Alkaline Phosphatase) probe activity. The solution is a solvent free buffer solution containing stabilized pNPP using sodium azide as preservative. In kinetic assays p-nitrophenol appears yellow and is measured at 405 /650 nm. If stopped reactions are preferred, add equal amounts of 1 .0 M s…

The liquid BCIP/NBT is the most commonly used substrate for colorimetric determination of Alkaline Phosphatase (AP) activity in membrane tests. We offer an aqueous buffered solution containing NBT (NitroBlue Tetrazolium) and BCIP (Bromo-Chloro-Indolyl Phosphate) forming a blue/purple precipitate at the positive sites. The colour develops when AP catalyses the dephosphorylation of BCIP. The intense blue/purple precipitate is…

TMB (3,3´,5,5´- tetramethylbenzidine) is a substrate for horseradish peroxidase (HRP). Our mono-component, liquid TMB solutions combine TMB, substrate buffer and hydrogen peroxide for a safe, ready-to-use, one step, chromogen system. The products do not contain harmful solvents. Recommended for ELISA procedures, liquid TMB yields a soluble blue end product read at 655 nm. The TMB reaction may be stopped with 0.2 M H2SO4 resu…

This new type of TMB with a red indicator combines all the important qualities of TMB ONE, eliminating possible mistakes during pipetting. Further the red colour may be useful in automatic analyzers giving the warning "Reagent low" when it is time for filling up the substrate.The red indicator disappears after addition of the stopping solutionand will neither affect the sensitivity nor the stability of the substrate. Stability…

The TMB PLUS has a higher activity level, resulting in a higher sensitivity and a reduced incubation time than found using the TMB ONE. TMB is a substrate for HRP. The mono-component, liquid TMB solution combines TMB, substrate buffer and hydrogen peroxide for a safe, ready-to-use, one step, chromogen system.The product does not contain harmful solvents. Recommended for ELISA procedures, liquid TMB yields a soluble blue end pr…

This new type of TMB with a red indicator combines all the important qualities of TMB PLUS, eliminating possible mistakes during pipetting.Further the red colour may be useful in automatic analyzers giving the warning "Reagent low" when it is time for filling up the substrate. The red indicator disappears after addition of the stopping solution and will neither affect the sensitivity nor the stability of the substrate. Stabili…

TMB is a substrate for HRP. Our mono-component, liquid TMB solution combine TMB, substrate buffer and hydrogen peroxide for a safe, ready-to-use, one step, chromogen system.The products do not contain harmful solvents. The TMB X-tra is a unique TMB substrate with an excellent resistancy and the highest sensitivity.

This TMB X-tra with red indicator combines all the important qualities of TMB X-tra eliminating possible mistakes during pipetting.Further the red colour may be useful in automatic analyzers giving the warning “Reagent low” when it is time for filling up the substrate. The red indicator disappears after addition of the stopping solution and will neither affect the sensitivity nor the stability of the substrate.

The useful image capture software ProgRes® CapturePro is included in the delivery of each ProgRes® camera free of charge. Whether for simple image documentation or demanding image analysis: with merely three mouse clicks you can optimize your images – thanks to the automatic functions included in ProgRes® CapturePro software. CapturePro supports the excellent quality of ProgRes® microscope cameras and delivers optimal image…

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Contents: One pre-coated microtiter plate and all reagents Storage Conditions: Keep at 4ºC for greatest stability. Range: 12.5 – 500 pg/ml Speed: Overnight incubation (26 hrs. 15 min.) Specificity: Mouse IFN-αA. No cross-reactivity with mouse IFN-β or IFN-γ. No cross-reactivity with human IFN-α.

In 2008 Gentronix launches a new S9 protocol to extend the application of the GreenScreen HC assay to include the detection of genotoxic metabolites. Many pharmaceuticals only present a genotoxicity hazard after metabolism and such chemicals are called pro-mutagens or pro-genotoxins. Generally, although not exclusively, the liver is considered responsible for the “metabolic activation” (MA) of promutagens. However, none of t…

Aitken Scientific Ltd, a leader in process control and automation, has recently become the European reseller of Comply’s process monitoring solution, Skyline. Skyline is widely applicable to anyone who needs to ensure the quality of their manufacturing processes, and the Statistical Process Control (SPC) information it provides will be of value in particular to customers focussed on GxP environments, such as the biotech and ph…

ATP luminescence assay for quantitative evaluation of proliferation and cytotoxicity of cultured mammalian cells. The 1step luciferase ATP assay format only requires one addition step, and can be used for continuous processing.

Advantec Japan, manufactures two great fraction collectors which can be used for both HPLC and other types of fraction collecting. Both units offer exceptional flexibility from the rugged x-y-z operation High quality Construction Wide choice of racks Software compatible Large sample capacity Prep option Collect by time, vol, drop or peak signal detection  CHF100SA Routine Collector A low cost Fraction Collecto…

Atlas Software is an easy to use PC based application for control and analysis of experiments. Whole systems including stirrers, circulators, RTDs, pumps, balances etc. can be configured using virtually any manufacturer’s apparatus. The “drag and drop” interface means recipes can be created, changed and saved with a click of a mouse.