Drug discovery > Pre-Clinical Development Products & Reviews

This kit is used for the non-radioactive quantification of ToxReporter protein that is secreted into cell culture media. One kit is sufficient to measure 38 unknown samples in duplicate.

LifeXtend™ conjugate stabilizer/diluent is a proprietary multi-component reagent system that stabilizes antibody-HRP conjugates both at 4°C and at ambient temperature. By using LifeXtend™ HRP stabilizer/diluent in antibody conjugation the HRP conjugate can be stabilized during use and stored as pre-diluted, ready-to-use reagents thus eliminating waste and improving consistency from experiment to experiment. LifeXtend™ shows…

Experience Better Productivity and Save Resources Too RapidFire data correlates identically with traditional LC-MS/MS methods Analyses are performed at a 10+ fold increase in cycle throughput, enabling us to provide 3 day turnaround RapidFire In Vitro ADME Analysis Services increase efficiencies while preserving your lab’s assay method integrity. We use the RapidFire 360 high-throughput TOF system to analyze CYP inhibition/ind…

This kit enables simultaneous measurements in the same cell of six independent parameters that monitor cell health, including cell loss, nuclear size and morphological changes, mitochondrial membrane potential changes, cytochrome c release, and changes in cell permeability.

The BrdU and Ki67 Cell Proliferation HCS Reagent Kits are for simultaneous quantification of DNA replication and Ki67 proliferation marker in the same cell.

The Multiparameter Cell Death Detection Kits for high-content screening (HCS) enable simultaneous quantitation of LC3B protein on autophagic vesicles, cytochrome c localization and its release from mitochrondria, cell membrane integrity and its permeability and nuclear morphology and DNA content.

The micronucleus assay is an important component of genetic toxicology screening programs.  Micronuclei arise from acentric chromosomes and lagging whole chromosomes. 

The Autophagy & Proteasome Function: LC3B and Poly-Ubiquitin Detection Kits enable quantitation of LC3B protein on autophagic vesicles and ubiquitin on polyubiquitinated proteins.

The iNOS Activation Kits measure cytoplasmic induction of the iNOS enzyme via activation of one of the many inflammatory pathways.

The Cellomics Phospho-ATM Activation Kit contains optimized reagents for the detection and quantitation of phosphorylated ATM (Ser1981) in the nuclei.

The Mitotic Index HCS Reagent Kit provides high-content screening (HCS)-quality fluorescence reagents and a validated protocol for measurement of mitotic index, or the fraction of cells undergoing cell division within a population.

Autoclavable caps that are designed to ensure the ultimate in product safety. The liners are made of a nontoxic white styrene-butadiene rubber and are faced with Teflon®, which offers excellent chemical resistance. Models available in range are the; • 13-425 Black Phenolic Cap with TFE Liner • 15-425 Black Phenolic Cap with TFE Liner • 22-400 Black Phenolic Cap with TFE Liner • 24-400 Black Phenolic Cap with TFE Liner For mor…

R&D Cell-Based ELISA - Dual fluorescence detection of two biomolecules simultaneously in the context of a whole cell R&D Systems Cell-Based ELISAs permit the simultaneous detection of two proteins in the same microplate well without the need for lysate preparation. Cell-Based R and D ELISA Kits come in two formats: phospho-protein kits contain antibodies to measure both the phosphorylated and the total protein, while total p…

Micro-ruled coverslip for cell culture with microscopic identification and measurement markers.

Disposable, all plastic hemacytometer with 2 counting chambers.

The Vision diode array spectrophotometer offers 16 predefined methodologies for nucleic acid quantification (DNA, RNA, and oligonucleotides), protein assays (BCA, Biuret, Bradford, and Lowry) and for cell culture density measurements. Additionally, the Vision can accomodate up to 90 custom protocols. The visualization of the nucleic acid scan with the full graphic display is particularly useful, especially for RNA samples wh…

BlueScreen HC is based on the fast, accurate GreenScreen HC genotoxicity assay from Gentronix Ltd. BlueScreen HC uses the same human-derived, p53-competent TK6 cells to host a patented reporter system that exploits the proper regulation of the GADD45a gene. However, in place of GFP, BlueScreen HC utilizes a luciferase from the marine copepod Gaussia princeps to generate a luminescent output. The BlueScreen luminescent assa…

Continuously variable speed makes the Vortex Mixer VX-200 useful for a variety of applications, from gentle mixing to resuspending pellets. The unit has a circular orbit, rather than the elliptical orbit found on many other vortexers. This allows a vortexing motion to be achieved even at low Many speeds, a task that cannot be accomplished with eliptical orbit units. Many vortex mixers prevent excessive vibration with added wei…

Efficient processing of liquid volumes up to 20 litres • Supor membrane has high flow rates and throughputs, and is ideal for solutions where low protein binding is required. Not recommended for use with some ketones. • Built-in prefilter extends filter life when viscous or particulate solutions such as serum-containing media are processed. • Upstream air vent prevents vapor lock. • Manufactured without the use of adhesives to…

Fast, final filtration and high throughputs for liquid volumes up to 150 litres • Provides higher throughputs and faster flow rates than similarly-sized competitive devices. • Ideal for solutions requiring low protein binding. • Saves money by increasing throughput with available built-in prefilter. • 100% integrity testing assures sterile filtrate. • 0.1 µm Supor membrane version ensures sterile, mycoplasma-free cell culture…

High air flow rate venting applications • Exhibits high air and liquid flow rates provided by 300 cm2 PTFE membrane. • Offers broad chemical compatibility provided by PTFE membrane and polypropylene housing. • 100% integrity tested to provide the high level of confidence you require.

Our Columbus™ Image Data Storage and Analysis system is an instrument agnostic image analysis and management platform.  NEW! Signals Image Artist™ is our next-generation solution for image analysis and management.

High Content Analysis (HCA) is rapid, automated microscopy providing quantitative image acquisition and analysis. Using Millipore’s superior-quality reagents in ready-to-use kits and cell-based assays that incorporate the power of HCA, researchers around the world are able to learn more about relevant functional cell biology in many different systems, including assessment of DNA damage and apoptosis. Millipore’s HCA kits inclu…

Hyborg is a fully automated device for processing and analysing hybcells (cylindrical DNA and protein microarrays). Hyborg integrates thermocycler, hybridisation station and scanner into a single device. All processing steps - from temperature profiles or exchange of liquids to multi-color scanning - are computer-controlled and documented. Hyborg's concept of totally integrated automation guarantees maximum reproducibility o…

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…