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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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PathDetect GRE Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems. When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element.

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PathDetect ISRE Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems. When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element.

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PathDetect LILRE Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems. When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element.

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PathDetect NFAT Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems.  When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element. For ultimate flexibi…

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PathDetect p53 Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems. When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element.

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PathDetect SRE Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems. When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element.

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PathDetect SRF Cis-Reporting System

Agilent Technologies

Determine if a gene product or compound activates pathways leading to specific enhancers with our PathDetect Cis-Reporting Systems. When PathDetect cis-reporting and expression plasmids encoding your gene of interest are co-transfected into mammalian cells, increased reporter activity indicates transcription activation and involvement of your gene product in the pathway leading to the enhancer element.

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PathDetect c/EBP Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect DR1/RXRE Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect DR3/VDR Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect DR4/TR Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect DR5/RARE Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect Egr-1 Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect GRE Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect LILRE Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect NFAT Cis-Reporter Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect p53-Luc Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect pAP-1-hrGFP Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect pAP1-Luc Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect pCIS-CK Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect pCRE-hrGFP Cis-Reporting Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect pCRE-Luc Plasmid

Agilent Technologies

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

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PathDetect pFA-ATF2 Plasmid

Agilent Technologies

The PathDetect in vivo signal transduction pathway trans-reporting systems are designed for specific, rapid, and convenient assessment of the in vivo activation of transcription activators and upstream signal transduction pathways. The systems are useful for identifying whether a newly cloned gene is involved in a signal transduction pathway, and if so, at which step of the pathway.  Identify specific stimuli that leads to th…

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PathDetect pFA-cFos Plasmid

Agilent Technologies

The PathDetect in vivo signal transduction pathway trans-reporting systems are designed for specific, rapid, and convenient assessment of the in vivo activation of transcription activators and upstream signal transduction pathways. The systems are useful for identifying whether a newly cloned gene is involved in a signal transduction pathway, and if so, at which step of the pathway.  Identify specific stimuli that leads to th…

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PathDetect pFA-CHOP Plasmid

Agilent Technologies

The PathDetect in vivo signal transduction pathway trans-reporting systems are designed for specific, rapid, and convenient assessment of the in vivo activation of transcription activators and upstream signal transduction pathways. The systems are useful for identifying whether a newly cloned gene is involved in a signal transduction pathway, and if so, at which step of the pathway.  Identify specific stimuli that leads to th…

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