Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Centricon Plus-70 Centrifugal Filter Units

Merck

• Concentrating and desaltingchromatography column eluates• Concentrating monoclonal antibodies• Concentrating proteins or viruses from culture supernatants• Clarifying tissue homogenates and cell lysates• Buffer exchange or diafiltration

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Montage® Antibody Purification Kits

Merck

Montage Antibody Purification Kits are designed for fast and easy antibody purification from serum, ascites or cell culture supernatants. The kits include spin columns pre-packed with high capacity PROSEP-A or G media. There are no pumps to setup. No columns to pack. All you need is a centrifuge to purify 10–20 mg in less than 60 minutes.The protocol is easy to follow and, unlike traditional gravity flow methods, the use of ce…

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25 mm Automation Compatible Filter Units

Merck

Automation compatible filter units from EMD Millipore are specially designed to provide efficient filtration for dissolution and other automated sample preparation applications.Choice of Filter Media: Automation compatible filter units are available in a variety of membrane types and pore sizes, including units with prefilters for particulate-laden samples.Automation Compatible Packaging: The 200 pack comes preassembled in 8 t…

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Millex Filter Units

Merck

Millex filter units with hydrophobic Fluoropore membrane are ideal for sterilizing gases, venting sterile containers, and sterilizing or clarifying organic solutions. Specialized filter units protect hemodialysis transducers from blood and moisture. 50 mm Millex filter units are also used for vacuum line protection. All units are bi-directional

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13 mm Non-sterile Millex Filter Units

Merck

This 13 mm syringe filter with a Hydrophilic Polyethersulfone membrane, for non-sterile filtration, has a 0.45 micron pore size used in preparation of aqueous & mild organic solutions prior to chromatography or other instrument analyses.

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Luminata™ ELISA HRP Substrates

Merck

The Luminata ELISA HRP chemiluminescent substrates provide three major advantages:High sensitivity for detecting as little as 0.1 pg of proteinBroad dynamic detection range (up to 2,500-fold), enabling a wide range of quantitation.Flexibility to adjust ELISA signal strength

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SPE - Solid Phase Extraction Workstation

Xiril AG

The solid phase extraction (SPE) workstation can be used on Xiril pipetting workstations for automated nucleic acid purification based on vacuum technology. All pipetting steps of several different nucleic acid purification kits can be automated on a Xiril liquid handling workstation. Xiril’s very space saving SPE vacuum station comprises two positions, one in the front for washing steps and another in the back for the elution…

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Magnetic PlateX - Magnetic bead separation device

Xiril AG

The magnetic bead separation device Magnetic PlateX can be used with a Xiril pipetting workstation for automated nucleic acid purification based on the magnetic beads technology. Speed up the process of nucleic acid purification with a magnetic beads kit using the Magnetic PlateX on a Xiril robotic workstation. All pipetting steps are taken over by the robot and the plate gripper “Plate GripX” automatically carries out the tra…

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Tube-ScanX LR - Barcode scanner

Xiril AG

The Tube-ScanX LR is the new scanner for the automated reading of barcodes on tubes on a Xiril liquid handling robotic workstation. The barcode scanner “LR” is equipped with a laser reader for a fast record of all barcodes on tubes without interruption while reading. The laser camera with autofocus is mounted fix on the worktable. It doesn’t have to be moved whereas the tube holding racks are drawn with two of the pipetting ad…

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Plate-ScanX - Barcode scanner

Xiril AG

The Plate-ScanX enables microplate identification for data tracking in an automated liquid handling process on a Xiril robotic workstation. Xiril’s plate scanner device allows reading of 1D and 2D barcodes on the side of microplates. The plate gripper of the Xiril liquid handling workstation picks up the plate and presents it in front of the barcode scanner camera.

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96 channel pipetting head

Xiril AG

Speed up your automated procedures and increase the throughput of your pipetting processes with 96 channels working in parallel! Xiril’s liquid handling workstations Neon100 and Neon150 can be equipped with a 96 channel pipetting head, using air displacement technology. The pipetting range from 3-200µl allows liquid transfers into 96- and 384well micro- and deep well plates in both single- and multi-pipetting modes. The 96 cha…

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ToxCount™

Active Motif

ToxCount™ provides a two wavelength cell viability assay based on determination of live and dead cells. The assay uses fluorescent dyes that measure permeability of the plasma membrane of dying cells and the ability of living cells to retain intracellular esterases, respectively. Live cells are distinguished by the presence of ubiquitous intracellular esterase activity, determined by the enzymatic conversion of the non fluores…

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Automated Pipetting - Neon 100

Xiril AG

Who else can provide targeted solutions for your medium to high throughput applications with highest flexibility on such a small robotic workstation? The Neon technology crosses boundaries with up to 8 independent pipetting channels and its unique combination of liquid and robotic handling for all your laboratory tasks including plate handling, barcode reading, heating&shaking, extractions etc. Space saving on a small footpri…

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AcroPak™ 200 Capsules with Supor® EKV Membrane

Pall Life Sciences - Laboratory, Food, Beverage

For Buffers, Tissue Culture Media, and Other Biological Fluids. Newer technology recommended for simplified scale-up High filtration area and compact size are ideal for upscale trials Minimal hold-up volume Good wettability for reliable integrity test Sealed membrane and housing uses fusion technology to eliminate potential extractables Gamma sterilized, non-pyrogenic, and provided with a removable filling bell (except sanit…

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AcroPak™ 400, 800, and 1500 Capsules With Supor® EKV Membrane

Pall Life Sciences - Laboratory, Food, Beverage

For Cost-Effective Filtration of Buffers, Tissue Culture Media, and Other Biological Solutions. Newer technology recommended for simplified scale-up Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders Encapsulated format for ease of use Extended life with built-in MachV asymmetric prefilter layer for maximum flow and throughput performance Low adsorption and hi…

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AcroPrep™ Advance 96-Well Filter Plates for Multiplexing

Pall Life Sciences - Laboratory, Food, Beverage

Superior Bead Recovery and Low Levels of False Positives Ensure Assay Reproducibility. Smooth well wall provides efficient bead recovery, ensuring reproducible results lot after lot High performance membrane does not trap microspheres in the membrane matrix In serological assays, Supor® membrane effectively removes IgG complexes, thus reducing nonspecific reactivity of the microspheres and reducing false positives New well des…

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AcroPrep™ Advance 96-Well Filter Plates for Solvent Filtration

Pall Life Sciences - Laboratory, Food, Beverage

Robust Chemical Resistance Provides Compatibility with Harsh Organics. Chemically resistant materials provide a stable platform to process samples in organic solvents Inert materials of construction ensure complete recovery of samples and low non-specific binding New well design results in faster, more uniform filtration rates across the plate and reduces hold-up volume Innovative outlet tip geometry provides direct flow of sa…

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AcroPrep™ Advance Filter Plates for Lysate Clearance

Pall Life Sciences - Laboratory, Food, Beverage

The AcroPrep™ Advance filter plates for lysate clearance effectively remove cellular debris quickly and allow for the use of additional wash steps to maximize sample recovery. Filtration can be accomplished by either vacuum manifold or centrifugation, ultimately maximizing your choice in protocols. The purification of biomolecules (DNA, RNA and proteins) from prokaryotic and eukaryotic cell lines can be problematic. The AcroP…

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