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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Micronucleus V2 Image Analysis BioApplication for Genotoxicity

The Micronucleus V2 BioApplication is a powerful image analysis algorithm for identifying and quantitating the rare event of micronucleus formation as a measure of genotoxicity.  Because it can screen a 96-well plate in under 8 hours, it enables screening for genotoxic compounds in an automated, objective manner.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for th…

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Molecular Translocation V2 Image Analysis BioApplication for Kinase and transcription factor activation

Molecular Translocation V2 is an advanced image analysis application for quantitating simultaneous cytoplasm-to-nucleus translocation of multiple targets.  It features subpopulation selection and cross-correlated responder analysis of up to 5 distinct targets, allowing study of signaling pathways.  This application has been biologically validated, enhancing confidence in your image-based data.    Available for the Cellomics Ar…

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Morphology Explorer V2 Image Analysis BioApplication

Morphology Explorer V2 is a powerful general-purpose image analysis application for measuring size, shape, and distribution of cells, colonies, and subcellular components.  It performs sophisticated calculations in a turn-key, automated manner allowing higher throughput of complex cell-based assays.  This application has been biologically validated, enhancing confidence in your image-based data.    Available for the Cellomics…

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Cell Health Profiling V2 Image Analysis BioApplication for Apoptosis and Cytotoxicity

Cell Health Profiling V2 is a flexible image analysis application employing advanced cell-level logic to detect and classify cell health-related events.  It analyzes patterns of cellular fluorescent labeling that can be used to classify cells as undergoing apoptotic, necrotic, or other cell death mechanisms.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for the Cel…

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Cell Cycle V2 Image Analysis BioApplication

The Cell Cycle V2 BioApplication is a sophisticated image analysis algorithm that performs automated analysis of the cell cycle phase of individual and populations of cells.  It reports cell cycle phase as well as the state of up to 3 target proteins for every cell analyzed, and correlates the target data with DNA content.  This application has been biologically validated, enhancing confidence in your image-based data.  Availa…

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Cytotoxicity V2 Image Analysis BioApplication

The Cytotoxicity V2 BioApplication is an image analysis application that simultaneously measures four markers of cytotoxicity (nuclear fragmentation/condensation, permeability, lysosomal mass-pH, and cell count) and reports individual and composite indicies of cytotoxicity.  The V2 version has been enhanced with object segmentation to allow clumped cells to be efficiently analyzed.  Available for the Cellomics ArrayScan VTI, A…

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Extended Neurite Outgrowth V2 Image Analysis BioApplication for Neurobiology

Extended Neurite Outgrowth V2 is an advanced image analysis algorithm that can quantitate neurite outgrowth with features such as cell body area and branch point quantitation, cell subpopulation analysis, Ability to analyze neuron subsets expressing up to two distinct neurotransmitters.  It reports all features at the cell, well, and subpoulation level, and is biologically validated to enhance confidence in your image-based da…

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Compartmental Analysis V2 Image Analysis BioApplication

Compartmental Analysis V2 is a powerful general image analysis tool for quantitating intracellular intensity changes in specific sub-cellular regions across multiple fluorescent channels.  It performs spot analysis and reports intensity ratios and differences among sub-cellular regions and/or different fluorophores.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for…

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Cell Motility V2 Image Analysis BioApplication for Cancer Research

The Cell Motility V2 BioApplication is a advanced image analysis algorithm for measuring the overall motility of cells.  It quantitates total distance traveled by each cell exposed to growth factor or compound for a quantiative assessment of cell motility.  The V2 version includes advanced analytical capabilities such as population analysis and object segmentation.  This application has been biologically validated, enhancing c…

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Spot Detector V2 Image Analysis BioApplication

Spot Detector V2 performs measurements of number, size, and other features of spots in cells.  It is an easy-to-use and essential component of any image analysis software suite.  This tool is excellent for measuring receptor internalization and trafficking, cell proliferation and counting, Analyzing populations. This application has been biologically validated, enhancing confidence in your image-based data.  Available for the…

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Cell Spreading V2 Image Analysis BioApplication

The Cell Spreading V2 BioApplication is an image analysis algorithm for measuring size and shape of cells.  It utilizes cells labeled with cytotskeletal fluorescent reagents to report whether cells have rounded in response to compound treatment, and includes advanced features such as population characterization and object segmentation.  This application has been biologically validated, enhancing confidence in your image-based…

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Neurite Outgrowth V2 Image Analysis BioApplication for Neurobiology

The Neurite Outgrowth V2 BioApplication is a streamlined image analysis algorithm for morphological analysis of neurite outgrowth. Utilizes fluorescent images of neurons and neurites stained for tubulin to quantitate the number and length of neurites in a population of cells.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for the Cellomics ArrayScan VTI, ArrayScan x…

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Cyto-Cell Membrane Translocation V2 Image Analysis BioApplication

Cyto-Cell Membrane Translocation V2 is a multi-channel image analysis algorithm for analysis of targets that translocate from cytoplasm to cell membrane.  It utilizes colocalization of fluorescent markers to report whether the target is co-localized to the membrane, and reports cells' behavior relative to a control population.   This application has been biologically validated, enhancing confidence in your image-based data.  A…

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GPCR Signaling V2 Image Analysis BioApplication

GPCR Signaling V2 is a high-content image analysis application for quantitation of the activation of G-protein coupled receptors.  Classifies cells into different phases based on pattern of receptor complex distribution and reports details of and percentage of cells with Type A and Type B recycling activity.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for the Cel…

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HitKit® HCS Reagent Kit - Multiparameter Apoptosis

The Multiparameter Apoptosis Kit comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of cell health by looking at several biological parameters.  This kit specifically labels nuclei, f-actin, and mitochondrial mass/potential in cells.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system.  Available in Evaluation Size (Five…

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Thermo Scientific HitKit® HCS Reagent Kit - Multiparameter Cytotoxicity 1

The Multiparameter Cytotoxicity 1 Kit  comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of cell health by looking at several biological parameters.  This kit contains indicators for nuclei, permeabilized cells, and lysosome mass/pH.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system.  Available in Evaluation Size (Five…

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eaZYX Image Analysis Software

MAIA SCIENTIFIC

eaZYX is a high-end and yet easy-to-use software platform for image acquisition, analysis that is composed of three parts: eaZYX-IMAGING, eaZYX-PROOFING and eaZYX-AUTOMATION.  eaZYX-IMAGING is the image analysis core software engineUnlike many image analysis softwares, eaZYX uses a holistic principle to ‘look’ at images.  It does not segment pixel information to pull forward certain features in the image using a ‘pixel-by-pixe…

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miVac Concentrators

Genevac

miVac is a range of centrifugal vacuum concentrators and freeze driers capable of removing water and organic solvents from a variety of sample formats including tubes, microplates, and vials. miVac concentrators come in 2 sizes, the smaller Duo and a larger Quattro. There is a choice of vacuum pump and rotor according to application and sample format.  To speed concentration built-in special runs for working with water and…

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DYMENSION 2

Syngene

Rapid Analysis of Multiple 2D Gel Sets DYMENSION 2 has all the features of DYMENSION 1 but has the added ability to detect and compare protein spot maps in multiple gel sets. The software offers many background correction and noise filtering features including a SYPRO® Ruby filter, which can detect and automatically remove spots caused by SYPRO® Ruby crystals adhering to the gel, thus saving users valuable time editing the…

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DYMENSION 3

Syngene

Quick and Easy Analysis of all 2D Gel Applications The exciting DYMENSION 3 software has all the functionality of DYMENSION 2, so can be used to analyse multiple gel sets. In addition, DYMENSION 3 is capable of analysing multi-stained fluorescent gel images stained with up to three contrasting fluorescent labels, for example, Cy™2, Cy™3 and Cy™5. This feature allows users to analyse multiple sets of any type of 2D protein…

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Immunoassays for the Hemostasis Factors

Aniara Corporation

The Zymutest line of Elisa kits are ready to use. Complete line of Enzyme Immuno assays, using 96 well microElisa plates, disposable in 12X8 well strips. Made for the exploration of plasma factors, fibrinolysis, autoimmunity, and markers of thrombotic diseases. They all include calibrators and controls.

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SampleScan 1000

The SampleScan1000's combination of a 2D tube reader and LCD display, make this one of the most intuitive single tube scanners available.  Place a tube on top of this unit and it will display the tube's ID number on the easy to read LCD.   A linear bar code scanner is easy to integrate with the SampleScan 1000 software to capture additional 1D bar code data associated with 2D bar coded tubes.   In addition, the SampleScan1000'…

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