Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.
The Spontaneously Hypertensive Stroke Prone Rat (SHRSP)was isolated from Wistar-Kyoto rats by Okamoto and Aoki in 1963. The A3 subline was transferred to the National Institutes of Health in 1975 from Yamori at generation F36. To Charles River in 2002. Model Properties: Coat Color: White (albino) Ideal For: stroke, ADHD model, nephropathy, hypertension, osteoporosis Strain Code: 324
Serving preclinical research laboratories in over 150 countries and facilitating your preclinical research quickly and efficiently. As experts in time and temperature critical shipments for over 30 years, Marken understands the importance of providing reliable supply chain support throughout the drug development process, including early R&D activities and preclinical safety testing.Marken provide global shipping solutions for…
DEVELOP THE BEST FORMULATION STRATEGY FOR YOUR DRUG TO ENSURE OPTIMUM PERFORMANCE. CrownBio provides a full range of services from pre-formulation development, pre-clinical formulation development and supporting analytical development services. Pre-formulation studies in combination with analytical methods are critical to identifying the best formulation strategy for a particular compound. Certain candidates present sp…
A new generation of SPME products.The Fast Fit Fiber Assemblies were developed by Chromline srl Prato Italy in cooperation with Supelco expanding the applicability of SPME for rapid sampling and analysis using multiple fiber assemblies. This product line is centered around the barcoded SPME Fast Fit Assemblies that can be automatically exchanged on a CTC CombiPAL type autosampler equipped with the Multi Fiber EXchanger (MFX) s…
The SPME-LC fiber probes are intended as single-use devices for the extraction of small molecules out of a fluid followed by solvent desorption and LC analysis.Traditional solid phase microextraction (SPME) fibers were developed with common GC type phases, which were primarily designed for extraction of volatile or semi-volatile compounds using thermal desorption as the means of introducing sample into the chromatographic colu…
Carboxen®/Polydimethylsiloxane (CAR/PDMS) SPME FibersSolid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of solid coatings. The…
Divinylbenzene/Carboxen/Polydimethylsiloxane (DVB/CAR/PDMS) SPME FibersSolid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of sol…
Seal and individualize 96- and 384-format 2D-barcoded storage tubes in a single process using the Thermo Scientific™ SampleSeal™ Heat Sealer. The foil-sealed tubes can be reliably stored at temperatures from -196° to +25°C, and easily pierced with manual or automated pipette tips, supporting compatibility across standalone or integrated storage applications. The SampleSeal creates single access samples which eliminate thaw an…
Our Flipper® racks present colorful solutions and space saving utility for tubes ranging in size from 0.2mL all the way up to 50mL. Available in different configurations to meet laboratory needs.
Ziath’s range of CryzoTraq™ cryogenic vials are designed for cryogenic storage of biological specimens at temperatures as low as -196°C. The range features outstanding leak resistance with a LDPE compression ring moulded into the screw cap. For information on the tests performed to ensure leak-free tubes, download our white paper. The tubes are available in 2ml or 5ml volumes with an internally or externally threaded cap. All…
The Ziath Linear Rack Scanner Version 2 is for use with the DataPaq™ Express, Deep Focus, High Speed and Multi-Rack Scanners. It is simply attached to the scanner using a bracket with a magnetic place holder. No assembly of the linear scanner is required, in addition the DataPaq™ Linear Rack Barcode Scanner is very simple to attach to existing 2D scanners, and offers easy installation. It can be attached to any side of the Da…
Assessment of Neuronal Activity Using Microelectrode Array. The eCiphrNeuro assay uses primary cultures of rat cortical neurons. Cyprotex’s neuronal assay uses high throughput microelectrode array (MEA) technology to monitor electrophysiological activity. Neurons grown on microelectrode arrays recapitulate many features of neurons in vivo, including spontaneous activity (spiking and bursting), plasticity, organisation a…
The SageELF is an automated, whole-sample fractionation system for NGS sample prep. SageELF, a whole-sample fractionation tool, is now shipping from Sage Science, developer of the Pippin automated DNA size selection system. The SageELF (short for Electrophoretic Lateral Fractionator) generates 12 contiguous fractions from a whole DNA sample, allowing scientists to generate libraries with multiple insert sizes from the same sa…
Advanced MRI coil technology delivers highest sensitivity in rat brain in vivo imaging
If you meet these needs: PCR setup in 96 and 384-wells plate Real time PCR setup in 96 and 384-wells plate Distribution Tube to plate transfer Plate to plate transfer Serial dilutions Hit picking Concentration normalization Plate compression/decompression SNP detection HLA genotyping PrimaDiag offers ACSIA XS PCR Edition. With the aim to increase your productivity, avoid contamination and improve work…
If you meet these needs: PCR and sequencing clean-up gDNA from various matrixes Plasmid preparation General liquid handling tasks Forensics Sequencing setup Sample preparation for LC-MS/MS analysis PrimaDiag offers ACSIA CleanUp Edition. With the aim to increase your productivity, avoid contamination and improve work efficiency, PrimaDiag designed ACSIA CleanUp Edition. It is a compact and robust automated pipe…
An ideal choice for drug delivery. Human albumin is ideally suited as a half-life extension approach for protein drugs. It is a natural, non-immunogenic plasma carrier protein which is extremely stable, highly soluble and large enough to avoid renal clearance. It is also widely accepted that albumin is recycled in the body, due to its interaction with its receptor, known as the neonatal Fc receptor (FcRn). FcRn is present on…
Recombinant albumin developed as an excipient for use in drug delivery and formulation. Recombumin Prime is the world's first and only supply of commercial, animal-free, recombinant human albumin, approved for use in the manufacture of human therapeutics.Used in the manufacture of the FDA and EMEA approved MMR™ II childhood vaccine from Merck and Co., Recombumin Prime USP-NF* is also being evaluated as an excipient, or ingred…
Derived from our proprietary S. cerevisiae yeast expression technology Recombumin Alpha USP-NF* has been developed to deliver quality and unprecedented performance benefits in our customers' applications including drug and vaccine manufacture, device coating, IVF media, specialized cell culture and cell therapy applications. Benefits: Animal-free Secure supply in large volume quantities cGMP for regulatory-compliance…
Flexible Multiport System for DURAN® GLS 80 Wide Mouth Bottles. The multi-port system consists of a GLS 80® screw cap with four ports. The tubes are fed through these ports and secured with inserts and screw connections. There is a choice of 5 inserts, each with different internal diameter depending on the application. Unused ports can be fitted with a blanking cap, if necessary. Sterile pressure compensation can be achieved…
GL 45 Screw caps with two or three ports. The connection system for DURAN® laboratory bottles are screw caps with GL 45 threads and two or three ports. Liquids can be added to or removed from bottles using the tube connections. Using a universal GL 14 tube adapter and different inserts, four different tube diameters can be used.This flexible, modular system provides the option of combining various components according to need…
DG safety caps are high-grade, flexible connection systems which have been designed specially for handling aggressive, gas-forming liquids. Available with 1, 2 or 3 connection ports with optional stopcocks, DG safety caps are particularly suitable for pharmaceutical and chemical applications. The safety caps come complete with v-ring seal (inside diameter 3.2 mm) and are ready for immediate use. V-ring seals are optionally ava…
Neptune™ HRP Conjugate Stabilizer preserves the activity of HRP-protein conjugates. This HRP stabilizer can be used to store concentrated stock HRP conjugates, reconstitute lyophilized conjugates, and dilute HRP conjugated antibodies to their useful working titer in ELISA tests and immunology-based techniques.Neptune™ HRP Conjugate Stabilizer is especially suited for ELISAs using anti-IgG HRP conjugates within traditional ant…
