Drug discovery > Target Discovery Products & Reviews

The Succinate-Glo™ JmjC Demethylase/Hydroxylase Assay is a bioluminescent assay for detecting the activity of JumonjiC (JmjC) histone demethylases and many Fe(II)/α-ketoglutarate-dependent dioxygenases that use α-ketoglutarate as substrate and release succinate as a product.

Count on minimal interference from test compounds when screening your compound library using luminescent, ATP-based kinase assays. We offer the ADP-Glo™ Kinase Assay, Kinase Selectivity Profiling Systems and hundreds of Kinase Enzyme Systems. These sensitive, reliable assays are easily scaled to meet your throughput needs and can be used with virtually any kinase and kinase substrate combination.

Automated Purification of High-Quality Total RNA with an Enhanced miRNA Enrichment

Sensitive Quantitation of Single-Stranded DNARequires less DNA than spectrophotometry

Directly Measure HDAC-Test Compound Affinity and Residence Time in Live Cells

BRET-Based Assays to Detect Protein:Protein Interactions in Live Cells

The BRAND Liquid Handling Station (LHS) pipetting robot handles routine tasks at high speed and with the highest precision.

LDH-Glo™ Cytotoxicity Assay detects cell death from a small number of cells, including 3D cell cultures, based on the release of lactate dehydrogenase.

The RealTime-Glo™ Annexin V Apoptosis and Necrosis Assay provides a no-wash, one-step Annexin V assay that allows continual monitoring of cell state to determine apoptotic onset using a plate-reading luminometer.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Antibody-dependent cell-mediated cytotoxicity (ADCC) is a mechanism of action of antibodies through which virus-infected or other diseased cells are targeted for destruntion by components of the cell-mediated.

The TNT® Coupled Reticulocyte Lysate Systems offer researchers an alternative for eukaryotic cell-free protein expression: a single-tube, coupled transcription/translation system. The TNT® Lysate Systems greatly simplify the process and reduce the time required to obtain in vitro translation results.

ProteaseMax™ Surfactant is a high-quality reagent for use in protein and peptide sample preparation.   ProteaseMax™ Surfactant solubilizes proteins and ensures fast and improved protein digestion with trypsin or chymotrypsin. It is designed to degrade over the course of a digestion reaction, yielding products that are compatible with downstream methods such as mass spectrometry (MS) and liquid chromatography (LC). For…

BRAND 96, 384, 1536-well polystyrene and polypropylene microtitration plates are excellent for cell and tissue culture, sample storage, immunological assays, and other applications. BrandTech Plates have 96, 384 and 1536 wells and are available with 330µL or 400µL well volumes. They are fully compatible with most standard plate readers and washers. Both sterile and non-sterile BRAND plates are available with rounded, V-shaped…

HaloLink - Promega Magnetic Beads for Covalent immobilization of HaloTag® fusion proteins.   Features of the Promega HaloLink Magnetic Beads: • Magnetic-Based: Easy and quick immobilization of HaloTag® fusion proteins with minimal loss of sample material. • Covalent Bond: Allows stringent washing of immobilized HaloTag® fusion protein, removing nonspecific proteins and enhancing overall data.  • Multiple Appli…

The Universal Vacuum Manifold system accommodates 24, 48 and 96 well plate configurations. This system includes a collection plate, extraction plate, manifold and vacuum gauge waste base for all wellplates.

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.

Stainless Steel Manifold -available in single, 3 and 6 station designs. The 3 and 6 multi-station manifolds allow the simultaneous processing of multiple samples.

Sino Biological has successfully developed anti-payload antibodies with high purity, specificity, and affinity, which are used for analyzing the plasma/serum PK profiles, DAR values, and drug load distribution of ADC drugs.

The Quick Western Kit provides a universal detection reagent that can be combined with the primary antibody incubation step, eliminating the need for a secondary antibody incubation step.

LICORbio Western Blotting Kits provide a convenient way to purchase reagents and membranes that are optimized for infrared fluorescence detection on the Odyssey infrared imaging systems.

The CellTag™ 700 Stain ICW (In-Cell Western™) Kits provide detection reagents for cell-based In-Cell Western Assays.

PAX-8 (MRQ-50) Mouse Monoclonal Antibody

P504s (13H4) Rabbit Monoclonal Antibody