Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Eppendorf DASware® discover

Eppendorf

With DASware discover user-defined process parameters can be added to process runs either online or retrospectively. DASware discover enables near real-time retrieval of runtime information from an SQL Server database by intuitive Microsoft Excel style queries. An embedded report generator provides recipe information, process information as well as event reporting. Utilizing the integral Chart Creator tool users can easily…

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Eppendorf BioFlo® 720

Eppendorf

Efficient and reliable scale-up is one of the major hurdles in modern biotechnology. To ensure maximum flexibility and scalability, the new BioFlo 720 bioreactor controller is compatible with the Thermo Scientific™ HyPerforma™ 5:1 Single-Use Bioreactors (SUBs). The well-known BioFlo software has been enriched with a variety of new features to automate your workflow.

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Eppendorf Conical Tube SnapTec® 50

Eppendorf

Done in a Snap: Snap Tec ® makes the difference. Fast and safe sample handling with Eppendorf Conical Tubes SnapTec ® 50. Accelerate your workflow especially multistep protocols with easy single-handed operation and directly applicable in your laboratory environment.

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Microplates Polypropylene

Eppendorf

The Eppendorf Polypropylene Microplates set new standards in terms of transparency, purity and stability! With the easy to read OptiTrack® matrix and a clarity, unique and unbeaten for polypropylene microplates, the identification of the correct plate or an individual well is easier, less error-prone and up to 30 % faster. Do you look for clear signals in fluorescence or luminescence detection even with low concentration sampl…

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epBlue ID: Secure Barcode Scanning - Tracking - Documentation

Eppendorf

With epMotion® you are able to automate all routine liquid handling tasks. Together with the epBlue ID software the epMotion can now be employed in application areas that require process documentation. The new module of the epBlue software system allows simple and safe data exchange with your laboratory information management system by using all common barcodes. Barcoded samples, plates and reagents will be scanned manually an…

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Glass Block Manifold

UCT, Inc.

Complete Vacuum Manifold System includes a glass block, Corian® manifold lid, a cover gasket, a vacuum gauge and valve assembly, teflon tips (16 or 24), an adjustable collection rack, bulkhead luer fittings, plugs (16 or 24), and manifold safety tray.

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synthWAVE microwave synthesis system

Milestone

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…

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traceCLEAN Acid steam cleaning system

Milestone

Cleaning various items used in ultra-trace analysis work is a critically important laboratory routine. traceCLEAN assures best cleaning quality of your TFM, glass and quartz parts for ICP/ICP-MS accessories. Any trace metal contaminants stay within the reservoir and do not come in contact with the cleaned trace accessories. The cleaning process with the traceCLEAN takes about an hour, enhancing the overall lab workflow. 

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ETHOS X for terpene extraction in cannabis labs

Milestone

ETHOS™ X microwave extraction line allows quick heating of the cannabis material for terpene isolation. Solvent-free extraction process takes only a few minutes and prevents any thermal degradation often noticed during use of conventional extraction methods. The fresh and characteristic taste of strain-specific cannabis is maintained, and high-quality terpenes are assured. The ETHOS X 2.0 is our latest generation of benchtop…

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flexiWAVE Microwave Synthesis System

Milestone

The new Milestone flexiWAVE overcomes the limitation of conventional microwave synthesis reactors, as it consists of a single microwave platform that, in combination with specific accessories, allows the chemists to perform classic glassware and high pressure synthesis, as well as solid-phase reactions.

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HaloTag® Mammalian Protein Purification System

Promega Corp.

It can be challenging to purify sufficient high-quality protein from mammalian cells. Boost protein recovery 30-60% with an optimized covalent protein tag, called HaloTag®. This complete kit offers strong improvements in recovery, purity, cost and protein functionality over historical FLAG® and poly-His tag purification strategies.

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ONE-Glo + Tox Luciferase Reporter and Cell Viability Assay

Promega Corp.

The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health. The assay uses a two-step, addition-only process to make these measurements in a single well of a plate, negating the need to run parallel assays. The first part of the assay is a nonlytic fluorescence assay (CellTiter-Fluor™ Cell Viability Assay) that measure…

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Magne™ Protein A and Magne™ Protein G Beads

Promega Corp.

Magne™ Protein G and Magne™ Protein A Beads are magnetic affinity beads with high specificity and high capacity for purification of immunoglobulins from cell culture media, ascites and serum samples.   These paramagnetic beads are composed of iron encapsulated in macroporous cellulose with low nonspecific binding. The magnetic beads use a novel attachment chemistry to immobilize recombinant Protein G or Protein A protein…

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MethylEdge™ Bisulfite Conversion System

Promega Corp.

The MethylEdge™ System provides an efficient method to rapidly perform bisulfite conversion with minimal DNA fragmentation, giving you more intact, converted DNA for downstream applications.   Start with as little as 100pg of input DNA for those precious, limited samples. Use the MethylEdge™ System with other DNA Methylation Workflow reagents to perform sensitive DNA methylation analysis on many sample types. The rapi…

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AttoPhos® AP Fluorescent Substrate

Promega Corp.

The AttoPhos® AP Fluorescent Substrate System provides a highly sensitive fluorescent alkaline phosphatase substrate.   The system includes AttoPhos® Substrate, AttoPhos® Buffer and Calibration Solution. AttoPhos® Substrate (2′-[2-benzothiazoyl]-6′-hydroxybenzothiazole phosphate [BBTP]) is cleaved by alkaline phosphatase to produce inorganic phosphate (Pi) and the alcohol, 2′-[2-benzothiazoyl]-6´-hydroxybenzothiazole (BB…

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MagneHis™ Protein Purification System

Promega Corp.

The MagneHis™ Protein Purification System provides a simple, rapid and reliable method for the purification of polyhistidine- or HQ-tagged, expressed proteins.   Paramagnetic precharged nickel particles (MagneHis™ Ni-Particles) are used to isolate polyhistidine- or HQ-tagged protein directly from a crude cell lysate using either a manual (requires use of a magnetic stand) or automated procedure. Using a tube format,…

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TNT® Quick Coupled Transcription/Translation System

Promega Corp.

The TnT® Quick Systems are convenient single-tube, coupled transcription/translation reactions for eukaryotic cell-free protein expression.   These cell-free expression systems combine the RNA Polymerase, nucleotides, salts, amino acids and Recombinant RNasin® Ribonuclease Inhibitor with the reticulocyte lysate solution to form a single TnT® Quick Master Mix. The TnT® Quick Coupled Transcription/Translation System is ava…

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ORF Clones

Promega Corp.

The Kazusa ORFeome Project was initiated to create a collection of human and mouse ORFs to enable the larger research community with a readily accessible, highly validated ORFeome. Kazusa DNA Research Institute (KDRI) is an academic Japanese research institute dedicated to genome-scale studies and the function of individual genes. KDRI is an active member of the global ORFeome Collaboration, and are experts in HUGE (Human Uni…

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Single Step (KRX) Competent Cells

Promega Corp.

The Single Step (KRX) Competent Cells are designed for efficient transformation and tightly controlled protein expression.   These cells consolidate the best attributes of these two steps into one strain to evaluate protein expression in E. coli. Transformation efficiencies are greater than 108 cfu/μg, similar to other highly competent cells. The single step cells are available in single transformation size (50μl). KRX a…

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Competent Cells

Promega Corp.

For standard cloning experiments competent cells are available in two formats: high efficiency at greater than 108cfu/μg for cloning (JM109, HB101), and subcloning efficiency at greater than 107cfu/μg (HB101). JM109 cells have the additional feature of blue/white screening for recombinants. For protein expression, JM109(DE3), BL21(DE3) or KRX competent cells can be used. The Single Step (KRX) Competent Cells are designed fo…

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Cell Line Authentication

Promega Corp.

Promega has partnered with ATCC to offer unparalleled STR testing service for human cell line authentication.   This service provides easy access to proven and comprehensive validation techniques. Promega's proprietary PowerPlex® and GenePrint® STR technology coupled with ATCC's considerable experience profiling human cell lines and extensive internal assets around STR profiling data interpretation is particularly r…

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