Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
The MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 13 Plex is used for the simultaneous quantification of the following Mouse analytes: TNF-α, MCP-1, IL-13, IL-12 (p70), IL-10, IL-7, IL-6, IL-5, IL-4, IL-2, IL-1β, IFN-γ, GM-CSF
The MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 22 Plex is used for the simultaneous quantification of the following Mouse analytes: GM-CSF, IFN-γ, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12 (p70), IL-13, MCP-1, TNF-α, G-CSF, IL-1α, IL-9, IL-15, IL-17, IP-10, KC, MIP-1α, RANTES
The MILLIPLEX® MAP Mouse Cytokine/Chemokine - Premixed 32 Plex is used for the simultaneous quantification of the following Mouse analytes: RANTES, MIP-1α, KC, IP-10, IL-17, IL-15, IL-9, IL-1α, G-CSF, TNF-α, MCP-1, IL-13, IL-12 (p70), IL-10, IL-7, IL-6, IL-5, IL-4, IL-2, IL-1β, IFN-γ, GM-CSF, Eotaxin, IL-2, IL-12 (p40), LIF, LIX, M-CSF, MIG, MIP-1β, MIP-2, VEGF
The MILLIPLEX®MAP Mouse Soluble Cytokine Receptor Panel is used for the simultaneous quantification of the following Mouse analytes: sCD30 (sTNFRSF8), sgp130, sIL-1RI (sCD121a), sIL-1RII (sCD121b), sIL-2Rα (sCD25), sIL-4R (sCD124), sIL-6R (sCD126), sRAGE, sTNFRI (sTNFRSF1A), sTNFRII (sTNFRSF1B), sVEGFR1 (sFlt-1), sVEGFR2 (sFlk-1), sVEGFR3 (sFlt-4)
The MILLIPLEX® MAP Canine Cytokine/Chemokine Panel is used for the simultaneous quantification of the following Canine analytes: IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, IL-15, IL-18, GM-CSF, IFN-γ, IP-10, KC, MCP-1, TNF-α
The MILLIPLEX® MAP Rat Cytokine/Chemokine Panel is used for the simultaneous quantification of the following Rat analytes: Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IP-10, Leptin, MCP-1, MIP-1α, RANTES, TNF-α, VEGF
The MILLIPLEX® MAP Rat Cytokine/Chemokine Panel - Premixed 23 Plex is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, Leptin, MCP-1, MIP-1α, IP-10, RANTES, TNF-α, VEGF
The MILLIPLEX® MAP Rat Cytokine/Chemokine Magnetic Bead Panel is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, Leptin, MCP-1, MIP-1α, IP-10, RANTES, TNF-α, VEGF
The MILLIPLEX® MAP Rat Cytokine/Chemokine Magnetic Bead Panel - Pre-mixed 23 Plex is used for the simultaneous quantification of the following Rat analytes: IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12 (p70), IL-13, IL-17, IL-18, Eotaxin, G-CSF, GM-CSF, GRO/KC, IFN-γ, Leptin, MCP-1, MIP-1α, IP-10, RANTES, TNF-α, VEGF
The Millicell μ-Angiogenesis activation and inhibition kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution.Continuous, live monitoring of cells as tubules formEven, flat slide surface prevents any liquid meniscus from forming, eliminating out-of-focus areasFull well visualization at low magnificationOptimized assay conditions in a miniatur…
PTEN hydrolyzes phosphate at the 3 position on the inositol ring of PtdIns(3,4,5)P3, and Ins(1,3,4,5)P4. Although PTEN has the consensus sequence of a protein tyrosine phosphatase, it dephosphorylates p-nitrophenylphosphate and other synthetic and protein substrates poorly. The greatest catalytic activity has been observed with the highly negatively charged, multiply phosphorylated polymer of (Glu-Tyr)n.
Suitable for use as a potent inhibitor of PKC and other protein kinases in vitro and in cultured cells.
Applications for Rat ESGRO® include use as a reagent for the in vitro maintenance of rat ES cells. Studies have demonstrated that rtLIF is more effective in maintaining the undifferentiated phenotype of rat ES cells than similar concentrations of murine LIF.
Fibroblast Growth Factor-acidic (FGF-a) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. Human FGF-acidic is a 15.8 kDa protein containing 140 amino acid residues.
Fibroblast Growth Factor-basic (bFGF) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. bFGF also exerts a potent angiogenic activity in vivo. Human bFGF is a 17.2 kDa protein containing 154 amino acid residues. Xu, et al. demonstrated that bFGF synergizes with the BMP antagonist noggin to sustain undifferentiated proli…
Fibroblast Growth Factor-basic (bFGF) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. bFGF also exerts a potent angiogenic activity in vivo. Human bFGF is a 17.2 kDa protein containing 154 amino acid residues. Xu, et al. demonstrated that bFGF synergizes with the BMP antagonist noggin to sustain undifferentiated proli…
Fibroblast Growth Factor-basic (bFGF) is a heparin binding growth factor which stimulates the proliferation of a wide variety of cells including mesenchymal, neuroectodermal and endothelial cells. bFGF also exerts a potent angiogenic activity in vivo. Human bFGF is a 17.2 kDa protein containing 154 amino acid residues. Xu, et al. demonstrated that bFGF synergizes with the BMP antagonist noggin to sustain undifferentiated proli…
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant human SCF is an 18.4 kDa protein containing 165 amino acid residues corresponding to the soluble secreted form of SCF.
M-CSF is a potent hematopoietic factor produced by a variety of cells including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is involved in development, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. The human is reactive in murine systems, but the murine molecule exhibits no activity on human cells.
Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein secreted by a variety of vascularized tissues. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis, and capillary permeability. Chemicon's mouse VEGF is a 39 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains comprising the full length mouse VEGF164 sequence and an N-terminal methionine resi…
Vascular Endothelial Cell Growth Factor (VEGF) is a secreted homodimeric protein secreted by a variety of vascularized tissues. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis, and capillary permeability. Human VEGF is a 38.2 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.
Fibroblast Growth Factor-8 (FGF-8) is a heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Recombinant Human FGF-8 is a 22.4 kDa protein containing 193 amino residues.
Human BAFF (B-cell activating factor belonging to the TNF family) is a novel ligand in the TNF family. BAFF plays an important role as co-stimulator of B-cell proliferation and function. Recombinant human BAFF is a soluble 17.0 kDa protein containing 153 amino acid residues, comprising the TNF-like extracellular domain of BAFF.
