Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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HybridSPE®-Plus Plates

Merck

Our HybridSPE ® -PLus plates effectively remove phospholipids and proteins from biological matrices in a simple pass-through method for accurate and reproducible LC-MS analysis. Unlike other phospholipid removal SPE products on the market, the unique retention mechanism of HybridSPE ® allows for separation of even very hydrophobic analytes from phospholipid contaminants.     

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Supel™ Swift HLB SPE Cartridges

Merck

Supel™ Swift HLB is a polymeric stationary phase for solid phase extraction (SPE) prior to instrumental analysis. It has both hydrophilic and lipophilic functional groups for the extraction of a broad range of compounds from aqueous samples. It retains analytes having diff erent polarities and Log P values due to its hydrophilic and lipophilic balance (HLB) property.

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Supelco® Smart SPME Fibers

Merck

Our Smart SPME fibers are equipped with a unique Smart chip that offers traceability, ease-of-use, and increased productivity. The smart SPME fibers are an extension of our expertise and innovation from traditional SPME coatings to smart SPME format for accurate, reliable, and consistent results.

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Supelco® Overcoated (OC) SPME Fibers

Merck

The over coating of fibers is a new technology in fiber coating to protect the SPME fiber from matrix components. This allows for immersion of the fiber directly into complex samples ensuring a more efficient extraction (e.g. of semivolatile compounds). Polydimethylsiloxane (PDMS) is used to overcoat a PDMS/divinylbenzene (DVB) fiber. The resulting fiber is more physically robust and resistant to chemical fouling and allows f…

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Supelco® Nitinol Core SPME Fibers

Merck

The nitinol-core of SPME fibers enhances the fiber performance and the precision of chromatographic results to enhance lot-to-lot and fiber-to-fiber reproducibility, increase fiber durability, and maintain selectivity and inertness compared to fused silica core fibers.

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IVARO Tube Handler AP

SARSTEDT AG

IVARO AP is more than just a liquid handler. It supports you in all types of sample preparation. Filling liquids into several identical tubes is just as easy as aliquoting samples into different containers and microtest plates, or creating dilution series.

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HuProt

CDI Laboratories, Inc

The HuProt™ Human Proteome Microarray is the most powerful tool ever created for autoantibody discovery. With over 21,000 human proteins and protein isoforms, HuProt is the most comprehensive human full-length protein array ever created. HuProt covers over 81% of human proteins in each major functional category of the proteome, as defined by the Human Protein Atlas. HuProt is used in a wide range of applications, including bio…

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PhIP-Seq

CDI Laboratories, Inc

VirScan™, HuScan ® , and MouseScan™ are applications of bacteriophage-display immunoprecipitation sequencing (PhIP-Seq), a powerful method of multiplexed analysis that combines high-throughput DNA sequencing with next-generation proteomics. PhIP-Seq is the highest-coverage antigen-specific assay yet developed, able to detect antibodies versus virtually any antigen via overlapping peptides.

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