Drug discovery > Target Discovery Products & Reviews

Delivers excellent uniformity and increased on-target rates

The Twist Standard Hybridization Reagent Kit v2 is the gold standard for efficient and specific binding of panel probes to your regions of interest. Coupled with Twist’s Catalog or Custom Panels, this standard hybridization workflow provides the optimal conditions for a broad range of content.

Enables sequencing of genes that are difficult or impossible to fully sequence with short read technology. 

Focus on important genes in pharmacogenomics that are critical to drug metabolism and patient therapeutic response.

Twist Diversity SNP Panel gives researchers a new flexible ethnicity-neutral gold standard to use for GBS

Deep coverage of clinically focused targets that allow for the study of methylation patterns that may be relevant to early cancer detection and diagnosis from tumor and liquid biopsy samples.

Streamline the identification of heritable disease-linked alleles, be it through carrier screening or pre- and post-natal testing.

The Twist Alliance Clinical Research Exome helps support the Broad Institute Genomics Platform and was designed using validated data from clinical patient samples.

The Twist Alliance Canine Exome developed in collaboration with the Broad Institute

The Twist Alliance CNTG Exome - 41 MB provides highly uniform coverage of the entire exome as well as full coverage of the mitochondrial genome.

Coverage of rare disease-associated genes 

Coverage of 72 selected cancer-associated genes

Detect Multiple Viral Pathogens from a Single Sample

Fast and Easy Library Workflows

Sequence the Whole Transcriptome

Outstanding Performance with Targetd Exome Sequencing

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

The Twist Bioscience MRD Rapid 500 Panel is a scalable target enrichment solution for monitoring minimal residual disease that leverages Twist’s silicon based DNA synthesis platform to design and manufacture capture panels for personalized medicine. 

The Twist UMI Adapter system offers a sensitive method for identifying low frequency somatic variants from cell free DNA (cfDNA). Libraries prepared with the UMI adapter system can be used for building consensus reads during analysis to increase variant detection sensitivity and to reduce PCR error contribution.

The Twist Pan-cancer Reference Standard is a high-quality, standardized control for use in the research and development of NGS-based liquid biopsy assays. 

Twist’s RNA sequencing workflows offer a complete NGS solution that produces uniform libraries for RNA sequencing.

The stainless-steel Polaris inventory racking systems are designed for long-term sample storage applications.

A 48 um soft non-permeable aluminum foil sealing film with 30 um layer of strong acrylic adhesive. FoilSealTM sealing foils remove cleanly from plate surfaces with no adhesive stringing, residue or contamination. Each sealing foil measures 78.3 x 129 mm and offers sufficient sealing area for all plate types (e.g. flat top and raised-rim). Chamfered corners result in no plate overhang for robotics applications. Features one end…

The encapsulated silicone adhesive is non-tacky until pressed against the sealing surface, at which time adhesive is released only in sealing areas to form the strongest available heat-resistant seal around each well on the plate. Adhesive on non-sealing areas of the film, such as directly over sample wells, remains encapsulated and inert. Excel ThermalSeal RTS films are sized to fit within the edges of raised-rim 96-well plat…

X-PierceTM sealing films are 89 µm thick vinyl with a 18 µm thick adhesive layer, designed for temporary protection from contamination and evaporation for samples in 96-well plates. A precut "X" over each well creates four flaps that easily bend downward when pushed by a robotic probe or pipet tip, allowing sample access without coring or adhesive fouling. A thin adhesive layer and special hairline cuts separating the X-Pierce…