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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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AXIS™ Axon Isolation Device, 150 µm

Merck

AXIS devices physically isolate developing neurites from each other and their respective neural cell bodies. In addition, the use of hydrostatic pressure during analysis provides researchers with an opportunity for targeted exposure of neuronal parts to growth factors, drug compounds, or other reagents of biological interest. This ability to selectively control exposure of neuronal outgrowth makes AXIS a powerful platform for…

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ArthroMAB; Kit, ten mice

Merck

Collagen-induced arthritis (CIA) in mice is widely used as an experimental model for rheumatoid arthritis (RA) in humans. CIA is mediated by autoantibodies, which bind to a particular region of type II collagen, such as CB11 (CNBR-digested fragment of type II collagen) (Terato et al, 1985). Antibody-mediated CIA can be induced by i.v. injection of a combination of four different monoclonal antibodies generated by the ArthroMAB…

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ArthroMAB; Kit, 25 mice

Merck

Collagen-induced arthritis (CIA) in mice is widely used as an experimental model for rheumatoid arthritis (RA) in humans. CIA is mediated by autoantibodies, which bind to a particular region of type II collagen, such as CB11 (CNBR-digested fragment of type II collagen) (Terato et al, 1985). Antibody-mediated CIA can be induced by i.v. injection of a combination of four different monoclonal antibodies generated by the ArthroMAB…

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ArthroMAB; Kit, 100 mice

Merck

Collagen-induced arthritis (CIA) in mice is widely used as an experimental model for rheumatoid arthritis (RA) in humans. CIA is mediated by autoantibodies, which bind to a particular region of type II collagen, such as CB11 (CNBR-digested fragment of type II collagen) (Terato et al, 1985). Antibody-mediated CIA can be induced by i.v. injection of a combination of four different monoclonal antibodies generated by the ArthroMAB…

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QCM Chemotaxis Cell Migration Assay, 24-well (3 μm), fluorimetric

Merck

The CHEMICON® QCM™ Chemotaxis 3 μm 24-well Migration Assay is performed in a Migration Chamber, based on the Boyden chamber principle. The 3 μm pore size of this assay's Boyden chambers is appropriate for studyingleukocyte migration. The quantitative nature of this assay is useful for screening of pharmacological agents. Each kit provides sufficient materials for the evaluation of 24 samples. The Chemicon QCM™ Chemotaxis 3 μm…

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QCM Chemotaxis Cell Migration Assay, 24-well (5 μm), colorimetric

Merck

The EMD Millipore 5 µm QCM™ Chemotaxis Assay 24-well- colorimetric utilizes a 5 µm pore size, which is appropriate for a subset of fibroblast cells or cancer cells such as NIH-3T3 and MDA-MAB 231 cells. Cells migrated toward chemoattractants were measured by crystal violet, a nucleic dye, and quantified by spectrophotometers. The system may be adapted to study different types of cell migration, including haptotaxis, random mig…

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QCM Chemotaxis Cell Migration Assay, 24-well (5 μm), fluorimetric

Merck

The CHEMICON® QCM™ Chemotaxis 5 μm 24-well Migration Assay is performed in a Migration Chamber, based on the Boyden chamber principle. The 5 μm pore size of this assay's Boyden chambers is appropriate for studying monocyte/macrophage migration. The quantitative nature of this assay is useful for screening of pharmacological agents. Each kit provides sufficient materials for the evaluation of 24 samples. The Chemicon QCM™ Chemo…

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QCM Chemotaxis Cell Migration Assay, 24-well (8 μm), colorimetric

Merck

The CHEMICON® QCM™ 24-well Cell Migration Assay (ECM508) eliminates cell pre-labeling and manual counting. The 24-well insert and colorimetric detection format allows for quantitative comparison of multiple samples. The CHEMICON® QCM™ 24-well Cell Migration Assay is performed in a Migration Chamber, based on the Boyden chamber principle. Each kit contains 24 inserts; each insert utilizes an 8 mm pore size polycarbonate membran…

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QCM Chemotaxis Cell Migration Assay, 24-well (8 μm), fluorimetric

Merck

The CHEMICON® QCM™ 24-well Cell Migration Assay does not require cell labeling, scraping, washing or counting. The 24-well insert and homogenous fluorescence detection format allows for large-scale screening and quantitative comparison of multiple samples. The CHEMICON® QCM™ 24-well Cell Migration Assay is performed in a Migration Chamber, based on the Boyden chamber principle. Each kit contains 24 inserts; each insert utilize…

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QCM Chemotaxis Cell Migration Assay, 96-well (8 μm), fluorimetric

Merck

The Chemicon QCM™ 96-well Migration Assay is ideal for the study of chemotaxis cell migration. The quantitative nature of this assay is especially useful for large scale screening of pharmacological agents. The 8 μm pore size of this assay's Boyden chambers is appropriate for migration studies of most cell types. Each kit provides sufficient materials for the evaluation of 96 samples. The Chemicon QCM™ 96-well Migration Assay…

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QCM Chemotaxis Cell Migration Assay, 96-well (5 μm), fluorimetric

Merck

The Chemicon QCM™ 96-well 5μm Migration Assay is ideal for studying chemotaxis cell migration. The quantitative nature of this assay is especially useful for large scale screening of pharmacological agents. The 5 μm pore size of this assay's Boyden chambers is appropriate for studying monocyte/ macrophage migration. Each kit provides sufficient materials for the evaluation of 96 samples. The Chemicon QCM™ 5μm 96-well Migration…

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QCM Chemotaxis Cell Migration Assay, 96-well (3 μm), fluorimetric

Merck

The Chemicon QCM™ 96-well 3μM Migration Assay is ideal for studying chemotaxis cell migration. The quantitative nature of this assay is especially useful for large scale screening of pharmacological agents. The 3 μm pore size of this assay's Boyden chambers is appropriate for studying leukocyte migration. Each kit provides sufficient materials for the evaluation of 96 samples. The Chemicon QCM™ 3μM 96-well Migration Assay is i…

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α Integrin-mediated Cell Adhesion Array Kit, colorimetric

Merck

The CHEMICON® Alpha Integrin-Mediated Cell Adhesion Array kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Integrin-Mediated Cell Adhesion Array can be completed within 1-2 hours, providing a rapid, quantitative assay for the characterization of alpha inte…

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β Integrin-mediated Cell Adhesion Array Kit, colorimetric

Merck

The CHEMICON® Beta Integrin-Mediated Cell Adhesion Array kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Integrin-Mediated Cell Adhesion Array can be completed within 1-2 hours, providing a rapid, quantitative assay for the characterization of beta integr…

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α/β Integrin-mediated Cell Adhesion Array Combo Kit, colorimetic

Merck

The CHEMICON® Alpha/Beta Integrin-Mediated Cell Adhesion Array kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Integrin-Mediated Cell Adhesion Array can be completed within 1-2 hours, providing a rapid, quantitative assay for the characterization of alpha…

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α/β Integrin-mediated Cell Adhesion Array Combo Kit, fluorimetric

Merck

The CHEMICON® Alpha/Beta Integrin-Mediated Cell Adhesion Array Combo Kit is designed as a cost effective, efficient method for identification of cell surface integrins. The kit format uses 12 x 8-well removable strips in a plate frame for convenience and flexibility in designing assays. The Alpha/Beta Integrin-Mediated Cell Adhesion Arrays can be completed within 1-2 hours, providing a rapid, sensitive, and quantitative assay…

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ECM Cell Adhesion Array Kit, colorimetric

Merck

The CHEMICON® ECM Cell Adhesion Array Kit (Colorimetric) provides an ECM Array microtiter plate with a colorimetric detection format, allowing for large-scale screening and quantitative comparison of multiple samples/cell lines. The kit is designed as a rapid (1-2 hours), cost effective, efficient method for characterization of cell adhesion.

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ECM Cell Adhesion Array Kit, fluorometric

Merck

The CHEMICON® ECM Cell Adhesion Array Kit (Fluorometric) provides an ECM Array microtiter plate with a homogenous fluorescence detection format, allowing for large-scale screening and quantitative comparison of multiple samples/cell lines. The kit is designed as a rapid (1-2 hours), cost effective, efficient method for characterization of cell adhesion

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QCM ECMatrix Cell Invasion Assay, 24-well (8 μm), colorimetric

Merck

The CHEMICON Cell Invasion Assay Kit is ideal for evaluation of invasive tumor cells. Each CHEMICON Cell Invasion Assay Kit contains sufficient reagents for the evaluation of 12 samples. The CHEMICON Cell Invasion Assay Kit is intended for research use only; not for diagnostic or therapeutic applications.

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QCM Collagen Cell Invasion Assay, 24-well (8 μm), Colorimetric

Merck

The CHEMICON Cell Invasion Assay is performed in an Invasion Chamber, based on the Boyden chamber principle. Each kit contains 24 inserts; each insert contains an 8 μm pore size polycarbonate membrane coated with a thin layer of polymerized collagen. The collagen layer occludes the membrane pores, blocking non-invasive cells from migrating through. Invasive cells, on the other hand, migrate through the polymerized collagen lay…

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QCM Collagen Cell Invasion Assay, 24-well (8 μm), Fluorometric

Merck

The CHEMICON Cell Invasion Assay is performed in an Invasion Chamber, based on the Boyden chamber principle. Each kit contains 24 inserts; each insert contains an 8 mm pore size polycarbonate membrane coated with a thin layer of polymerized avian collagen. The collagen layer occludes the membrane pores, blocking non-invasive cells from migrating through. Invasive cells, on the other hand, migrate through the polymerized collag…

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QCM ECMatrix Cell Invasion Assay, 24-well (8 μm), fluorimetric

Merck

The Chemicon® QCM™ 24-well Invasion Assay does not require cell labeling, scraping, washing or counting. The 24-well insert and homogenous fluorescence detection format allows for large-scale screening and quantitative comparison of multiple samples. The CHEMICON® Cell Invasion Assay is performed in an Invasion Chamber, based on the Boyden chamber principle. Each kit contains 24 inserts; each insert contains an 8 μm pore size…

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QCM ECMatrix Cell Invasion Assay, 96-well (8 μm), fluorimetric

Merck

The CHEMICON QCM™ 96-well Invasion Assay does not require cell labeling, scraping, washing or counting. The 96-well insert and homogenous fluorescence detection format allows for large-scale screening and quantitative comparison of multiple samples. The CHEMICON Cell Invasion Assay Kit is ideal for evaluation of invasive tumor cells. Each CHEMICON Cell Invasion Assay Kit contains sufficient reagents for the evaluation of 96 sa…

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