Drug discovery > Target Discovery Products & Reviews

CellBase CT is a new automated system designed for ex-vivo expansion of autologous cell therapy products. Developed with leading cell therapy organisations, CellBase CT scales up existing manual cell culture processes in T-flasks, enabling manufacture of cell therapy products derived from a wide range of cell types, including hES, iPS and adult stem cells. CellBase CT automates:CellBase CT automates the maintenance and expansi…

Fluorescence Protein Detection Test ProReveal is a highly sensitive fluorescence-based patented protein detection test for checking the presence of residual protein on surgical instruments after going through a washer disinfector process. This cost-effective test (conforms to BS EN ISO 15883-1) delivers objective, visual and measurable results, removing any doubt as to whether a decontaminated instrument is safe for reuse. Ke…

The Tube Auditor™ measures sample volumes and detects precipitate using high-speed vision technology. It gives confidence in the quality of your samples (at both collection and output) and helps reduce downstream costs and waste, which can arise from empty wells and precipitated samples. Applications include Compound Management, High Throughput Screening and Biobanking. 

The MultiPep RSi is a fully automated high throughput multiple peptide synthesizer based on a pipetting robot. Utilizing exchangeable modules, the MultiPep RSi can be configured to enable the synthesis of small scale peptide libraries, membrane bound peptide arrays (SPOT method), specialty peptides or PNAs, as well as high quality peptides in large scales up to 10 mmol. Due to this flexibility, the instrument can take the pl…

The MultiPep CF is a fully automated peptide synthesizer with a unique column module that allows the synthesis of long and difficult sequences. During the synthesis, reagents are continuously circulated and real time UV monitoring enables the automatic optimization of reaction parameters like deprotection, coupling times, and wash steps. This leads to a greater coupling yield, superior peptides, and also saves time and reduc…

The patent-pending EXP® Trap Column is rated for use at 20,000+ psi (1,400+ bar). This unique design connects directly to any injection valve (with 10-32 threads) or in-line with 1/16” stainless tubing for unparalleled convenience and efficiency. The EXP® Cartridge System enables chemists to quickly remove detergents or salts which can affect the ionization process in MS work. This trapping technique can concentrate the sampl…

The entire EXP® Stem Trap and reusable holder are only slightly larger than a standard HPLC fitting. Its slim architecture allows it to easily fit into crowded instrument compartments or to connect directly to tightly-spaced injection ports. When tightened by hand, the EXP® Stem Trap seals to 8,700+ psi. All configurations incorporate wrench-flats to enable flawless sealing to 20,000+ psi (1,400+ bar). The unique packed floati…

The EXP® Stem Filter features a choice of frit porosities integrated with our patented auto-adjusting stem for repeated ZDV connections with any 10-32 port. The entire filter stem and reusable holder are only slightly larger than a standard HPLC fitting. This slim architecture allows it to easily fit into crowded instrument compartments, tightly spaced injection ports, and anywhere else you need an extra level of protection ag…

The EXP® Nano Trap System is designed to remove detergents or salts which can affect the ionization process in MS work rated for routine use up to 20,000 psi.The new nano-scale traps are available in two formats – EXP® Nano Trap and EXP® Nano Trap HR. Both formats are available in 10 or 20 mm lengths and in a variety of bed volumes ranging from 0.25µL - 4.0µL. The EXP® Nano Trap follows a traditional trap column format, design…

OPTI-SOLV® Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing your analysis. While the availability of HPLC-grade solvents diminishes the need for pre-filtering, it is still imperative that a filtration device be installed in the reservoir. Placing a filter in the reservoir is an economical way to filter particles that may result from buffer sal…

A solid PTFE body keeps OPTI-SOLV® filter at the base of the bottle where a bottom-mounted titanium frit provides unrestricted solvent access. As always, Optimize makes installation as simple as possible - no tools or fittings required and includes 5 feet of pre-installed PTFE tubing. OPTI-SOLV Reservoir Filters employ a unique conical design inside the filter housing to prevent air bubbles from getting trapped and disturbing…

The user-friendly Hand-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Placeme…

The user-friendly Wrench-Tight OPTI-SOLV® In-Line Filter System is well suited for a number of applications, such as high temperature, high-pressure environments where quick changes are imperative. The unique swivel design allows frits to be changed without removing the connecting tubing. Just plumb it once and leave it. The frictional forces generated at the piston/seal interface inevitably lead to particulate shedding. Place…

The OPTI-LYNX™ Quick Connect Trap Columns allow you to quick-connect to any 10-32 valve/port for trapping or analytical column for pre-column filtration. With OPTI-LYNX™, accessing and changing the insert takes only a quarter turn. Replace traps, filters or change configurations in seconds, without tools. OPTI-LYNX™ traps and filters (ordered separately) come in several bed volume/ diameter/ porosity combinations, allowing you…

Thermo Scientific™ HyCryo Cryopreservation Media is a serum-free, animal origin-free product intended for cryogenic storage of your standard cell lines. HyClone™ HyCryo media is a serum-free, animal origin-free product intended for cryogenic storage for your standard cell lines. HyCryo gives you the recovery that you want from your cells with peace of mind knowing that your precious cells are faithfully preserved for your futu…

Thermo Scientific™ HyCryo-STEM is designed specifically for stem cells, with a serum-free formulation that maintains differentiation potential and minimizes spontaneous differentiation of stem cells. HyCryo-STEM provides impressive cell recovery and post-thaw growth of pluripotent stem cells (ESC and iPSC) and neural progenitor cells such as mouse cortical stem cells (MCSCs) and rat cortical stem cells (RCSCs). The serum-free…

The Pippin Link Group Control is the best way to reproducibly provide the highest quality size-selected DNA in high-throughput. It provides hardware and software for running up to eight Pippin Instruments from a laptop PC. Three linked-Pippins can produce up to 96 size selections in one day.

WHEATON BioBanking Solutions is a comprehensive offering of high quality products and customized services for your cryogenic needs.Whether you require the storage of irreplaceable samples in glass cryogenic ampules or plastic cryogenic vials, bar coding options for sample traceablity or for color coded storage and freezer boxes, WHEATON provides you with the tools that make your job easier and more efficient while having the c…

Gerhardt has created a complete line of Soxtherm models, creating the ideal opportunity to have a state of the art lab for Extraction systems. One of the most impressive units in the line is the Soxtherm 416, capable of six extraction places capable of holding both small and large beakers. The unit is capable of nearly all analytical areas in fat determination and sample preparation specifically: milk, cereal, meat, oil, fruit…

The new PHOTONIS Ion Mobility Spectrometer (IMS) Analyzer is a complete integrated assembly for simplified IMS analysis that features high resolving power (64-150) in a compact design. The unit combines PHOTONIS’ patented Resistive Glass products with a new robust ion gate technology to create an IMS analyzer which improves resolution and simplifies serviceability. Key components of the IMS Analyzer are made from Resistive Gla…

RFP -Trap® - use your fluorescence fusion as tag for biochemical studies Curiously RFP, a widely used labeling tag in cell biology, is rarely used for biochemical analyses. This may be due in part to limited RFP antibody availability and specificity as well as co-eluted heavy and light antibody chains that interfere with subsequent analyses. Superior results in a fraction of the time The ChromoTek RFP-Trap® overcomes these pro…

GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…

Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…

Fusion of proteins to Glutathione S-Transferase (GST) of Schistosoma japonicum is a common technique to increase solubility and expression level of a protein. Furthermore, GST-tagged fusion proteins are often used in protein-protein interaction studies. Both approaches require highly specific tools to isolate and detect GST fusion proteins. GST-Trap The GST-Trap is a highly specific and robust GST-binding protein coupled to ma…

DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…