Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
Streptavidin coated wells of the BioBind microplate offer biotin mediated binding for small or hydrophilic molecules. This surface is ideal for e.g. peptides, oligonucleotides and DNA hybridization assays. The streptavidin-biotin bond is extremely strong and stable, and utilizing this system problems associated with steric hindrance during the binding procedure can be avoided. Product detail: BioBind - Streptavidin Coated…
SeqSolve™ is an advanced and user-friendly software solution for the tertiary analysis of Next Generation Sequencing (NGS) data. By integrating state-of-the-art bioinformatics methods into one-click analysis workflows, SeqSolve is the only software able to provide scientists with such a combination of both cutting edge and intuitive user experience. Its Click And Go® technology enables the automatic processing of the data, whi…
5 mL capacity with round bottom Self-standing design Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Special base design allows vials to be locked into cryogenic rack and tray (Cat. No. 430525 or 431131) for single-hande…
An arrayed or non-arrayed BAC library is the preferred choice for downstream applications such as hybridization screening; full-genome sequencing; BAC end sequencing or physical mapping projects. Amount of clones received is based on a guaranteed coverage and 120Kb average insert size. HMW DNA isolation and QC by HMW DNA enzymatic digestion are included. Deliverables for ARRAYED BAC library: Clones will be arrayed and amplifie…
A pooled BAC library is an invaluable tool for PCR-screening. It allows for the easy retrieval of BAC clones of interest. This type of library is especially useful when genome size is large and creating an arrayed library is cost-prohibitive. We typically construct a minimum 5X BAC library and BAC clones are then pooled and distributed in 96-well plates. Each well will contain about 400-500 original BAC clones. HMW DNA isolati…
Our uncloned normalized cDNA is created using proprietary technology which features full-length-enriched and high quality size-fractionated cDNA. Our cDNA has been used successfully with FLX, Titanium an Illumina sequencing.
Our cDNA libraries feature full-length-enriched and high quality size-fractionated cDNA. cDNA library construction is usually done in slightly-modified versions of pBluescript or pcDNA3.1. Insert sizes will range from about 0.5Kb to 4Kb. Concerning QC steps, we evaluate the average insert size, empty clone rate and clone concentration/tube before shipping out. We always provide a gel picture of randomly selected clones showing…
APAgene™ GOLD Genome Walking Kits are designed to rapidly and reliably amplify unknown genomic DNA using our patented APA technology: 1. Isolate unknown genomic sequences flanking transgenes (including T-DNAs, gene traps, transposons), sequence-tagged sites (STSs) or expressed sequence tags (ESTs). 2. Isolate localized sequences flanking known sequences from large clones and genomic DNAs. 3. Sequence insert ends of large clone…
ASH is APA-based, full-length-enriched, single-stranded cDNA subtraction hybridization library. - ASH cDNA subtraction is full-length-enriched and independent of PCR suppression. - ASH cloning is directional and does not involve normalization. - ASH method provides non-exponential amplification before subtraction because double-stranded cDNA is not required. - ASH method has a better subtraction effect because 1) a high ratio…
Improve your cell analysis and use our powerful new transfection reagents: Efficiently transfect a broad spectrum of cells, including difficult-to-transfect cell lines and tumor cell lines. Generate physiologically relevant results using low cytotoxic reagents. Avoid time-consuming optimization using fast, reliable protocols.
Discover More, Sequence Less Built upon the NimbleGen Sequence Capture empirically optimized probe design algorithm with high efficiency uniformity of capture1, and now with expanded coverage of coding exons, SeqCap EZ Exome v3.0 offers increased performance. Capture the most comprehensive picture of the human exome with SeqCap EZ Exome Library v3.0. Based on the latest database builds and offering a 64Mb sequence capture, Seq…
The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…
The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…
Performance, Resolution, Speed. With its new detection system, the InnoScan 910 has the highest resolution and reading speed on the market. This user-friendly, two-color scanner is the ideal tool for reading current and future high-density microarrays.With outstanding sensitivity and signal-to-noise ratio derived from its highly regarded photometric properties, the InnoScan 910 is a confocal detection scanner fitted with 2 ex…
Simple, User-friendly, High performance.Mapix is characterised by its ease-of-use. It is a standard in the field of segmentation (automatic searching for microarray spots). Mapix has the most up to date requirements to browse data from microarray experiments quickly, with a high level of reliability and optimised productivity.Mapix can be customized, allowing users to add their own functions using its exclusive plug-in system.…
Absolute Automation Is True Walk-Away Freedom for: ■ Sample Preparation ■ Sample Processing ■ Results Analysis Only the TIGRIS® DTS™ System, with Absolute Automation, automates all phases of molecular diagnostics testing from sample preparation, amplification, and detection to reporting results. Integrating the TIGRIS DTS System with APTIMA® assay kits for nucleic acid testing (NAT) offers true freedom from hands-on processing…
The AbsoluteIDQ p150 Kit identifies and quantifies 163 analytes from 4 compound classes, i.e., acyl carnitines, amino acids, glycerophospho- and sphingolipids and hexose using an FIA-MS/MS method.The p150 Kit is an excellent choice for researchers who are looking for a cost-effective solution to measure metabolites under quality-controlled conditions in their own laboratory. The AbsoluteIDQ® p150 Kit is an easy-to-use and accu…
The AbsoluteIDQ p180 Kit enables standardized, quantitative and reproducible analysis of ca. 200 endogenous metabolites from several metabolite classes (acyl-carnitines, amino acids, biogenic amines, (lyso-) phosphatidylcholines, sphingomyelins, hexoses, steroids). The metabolite analysis is based on flow injection analysis (FIA-ESI-MS/MS) and LC-ESI-MS/MS. The possibility of measuring different biological matrices of differe…
Through these Metabolic Phenotyping Services we can help you to identify relevant metabolic biomarkers, accelerate your understanding of biochemical pathways and provide important information of the metabolomic state of a cell, tissue or living organism. Our technology platform offers mass spectrometry-based (FIA-, LC-MS/MS and GCMS) quantification of metabolites through multiple reaction monitoring (MRM) using triple quadrup…
The ultimate standard for autoclaveable bench-top fermentor systems Comes with all necessary controls and accessories for fermentation or cell culture Can operate in continuous, batch, and fed-batch modes Size range: 2.0-7.0 L Option to run up to 6 fermentors at a time from one station with our state-of-the-art BiOSCADA software system: offering countless options for control strategy, process engineering, and data manag…
The flexible & mobile laboratory fermentor for cultivation excellence: Designed for laboratory or small-scale production purposes In-situ sterilizable, with electrical heating system or steam heat exchanger As a modular system with glass or steel cylinders, can readily adapt to a wide variety of needs with minimum hassle Can operate in continuous, batch, and fed-batch modes Available as a cGMP fermentor for small-s…
The perfect link between laboratory and production: Designed for scale-up or production processes User-friendly and open-frame construction allows for easy installation and maintenance of this in-situ sterilizable fermentor, with steam heat exchanger Modular design gives flexibility when choosing controls and accessories for any biotechnological process. Size range: Choose from an option of 42L, 50L, or 75L stainless…
The pilot-scale fermentor for production perfection: Our largest off-the-shelve fermentor, in-situ sterilizable for use in pilot and production plants Straight-forward and user-friendly design, with flexible controls and accessories for whatever performance you are looking to achieve Size range: Total volume size ranging from 100L to 1000L and possibly beyond Controlled by our state-of-the-art BiOSCADA software: offer…
Flat bottoms with 112 µL total volume Recommended working volumes of 20 to 80 µL TC-treated for optimal cell attachment Nonreversable lids with condensation rings to reduce contamination Sterilized by gamma radiation and certified nonpyrogenic Individual alphanumeric codes for well identification Bulk packed 20 per bag
Flat bottoms Nonreversible lids with condensation rings to reduce contamination Individual alphanumerical codes for well identification Uniform footprint for ease in stacking Treated for optimal cell attachment Sterilized by gamma irradiation Certified nonpyrogenic
