Drug discovery > Target Discovery Products & Reviews

For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill is designed for lysis of mammalian blood, serum, or plasma samples, and the stabilization of nucleic acids. After the addition of Lysis/Binding Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or aft…

For use with:Cat. No. 03 172 627 001 MagNA Pure LC mRNA Isolation Kit II (Tissue) orCat. No. 03 330 591 001 MagNA Pure LC RNA Isolation Kit III (Tissue) For general laboratory use. The MagNA Pure LC RNA Isolation Tissue Lysis Buffer – Refill is designed for lysis and homogenization of fresh frozen tissue samples using a tissue homogenizer (see the MagNA Lyser Instrument) stabilization of total RNA and mRNA within samp…

For general laboratory use. The MagNA Pure LC mRNA Isolation Kit I - Lysis Buffer Refill is designed to lyse mammalian whole blood, blood cells, or cultured cells, and stabilize mRNA.After the addition of Lysis Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or after long-term storage) with the MagNA Pure LC…

The MagNA Pure LC Cooling Block, LC Centrifuge Adapters, holds 32 LightCycler® Centrifuge Adapters containing LightCycler® Capillaries (20 µl). The Cooling Block is designed to cool the capillaries during automated PCR setup by the MagNA Pure LC Instrument. In addition, the Cooling Block holds fifteen 1.5 ml reaction tubes (e.g., for master mixes). The stage of the MagNA Pure LC Instrument includes a cooling area, which is des…

The MagNA Pure LC Cooling Block, LC Sample Carousel holds one LightCycler® Sample Carousel (all formats) containing LightCycler® Capillaries. The Cooling Block is designed to cool the capillaries during automated PCR setup by the MagNA Pure LC Instrument. In addition, the Cooling Block holds sixteen 1.5 ml reaction tubes (e.g. for master mixes). The stage of the MagNA Pure LC Instrument includes a cooling area, which is design…

Application The MagNA Pure LC Cooling Block, Reaction Tubes, is used for placing thirty-two 1.5 ml reaction tubes, with screw caps, on the stage of the MagNA Pure LC Instrument. This Cooling Block can be combined with either the MagNA Pure LC Cooling Block, LC Centrifuge Adapters, or 96-well PCR Plate. The stage of the MagNA Pure LC Instrument includes a cooling area that is designed for various post-elution pipetting proces…

Application The MagNA Pure LC Cooling Block, A-Ring holds one or two A-Rings with bar codes. Application of the corresponding Post Elution Module of the MagNA Pure LC Software results in automatic filling of the A-Rings with purified nucleic acids and compatible PCR reagents, which are also positioned on the Cooling Block. The A-Rings are then ready to be transferred to an instrument platform for testing. The stage of th…

Application Tip Rack for placing of tip trays.

Reagent Reservoir Rack for placing reagent tubs.

The MagNA Pure LC Barcode Reader Quick Scan 1000 enables sample identification and tracking during the entire MagNA Pure LC purification run. It reads the bar code on primary tubes, as well as bar codes generated by the MagNA Pure LC Barcode Printer TLP 2844 (Cat. No. 03 576 094 001) for the MagNA Pure LC Sample Cartridges or Cooling Blocks.

The MagNA Pure LC Barcode Printer TLP 2844 facilitates sample identification, tracking, and documentation during MagNA Pure LC purification runs. It enables the user to print bar codes created by the MagNA Pure LC Software Version 3.0 for the MagNA Pure LC Sample Cartridges and/or non-barcode-labeled primary tubes. The MagNA Pure LC Barcode Labels (available separately, Cat. No. 03 531 520 001) are suitable for the new bar-cod…

The MagNA Pure LC Barcode Labels are designed for use with the MagNA Pure LC Barcode Printer TLP 2844 (Cat. No. 03 576 094 001). The labels are suitable for the new bar-code labeling area of the MagNA Pure LC Sample Cartridge.

The MagNA Pure LC Bar code Printer Ribbon is designed for use with the MagNA Pure LC Barcode Printer TLP 2844 (Cat. No. 03 576 094 001).

Application The MagNA Pure LC Cartridge Seal is an adhesive film used for sealing the MagNA Pure LC Sample Cartridge for storage purposes. The Cartridge Seals can be used at –80 to +37°C. To obtain a single sample without exposing others, simply cut through the cartridge seal of the desired well, then reseal the cartridge with a new Cartridge Seal. Quality The disposable plastics for the MagNA Pure LC Instrument meet stringe…

For use with the MagNA Pure Compact Nucleic Acid Isolation Kit I For general laboratory use. The MagNA Pure Bacteria Lysis Buffer is designed for: lysis of bacteria in many different samples of mammalian origin (e.g., urine, bronchoalveolar lavage [BAL], sputum, cerebrospinal fluid [CSF], swabs) or bacterial cultures stabilization of DNA in sample lysates purification of bacterial DNA with the MagNA Pure Compact Instru…

These Costar® Spin-X® centrifuge tube filters have a 0.22 µm pore CA membrane-containing filter unit within a 500 µL capacity polypropylene microcentrifuge tube. Cellulose acetate (CA) membranes provide fast flow rates and low protein binding Ideal for removing bacteria, particles, or cells from liquids, HPLC sample preparation and DNA removal from agarose or acrylamide gels. Nonsterile and certified nonpyrogenic and DNase-…

Feature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Sterile and certified DNase- and RNase-free Total volume is 2 mL

Assorted polypropylene caps inserts provide color-coding for easy sample identification Inserts are packaged in resealable bags 100 each of white, blue, red, green, and yellow Nonsterile Cap inserts fit all Corning cryogenic vials except Cat. No. 430289

Steroid Analysis – QUICK and EASY: BIOCRATES AbsoluteIDQ® Steroid reagents enable up to 17 steroids from human serum to be quantified simultaneously and reliably using LC-MS/MS. Fully customizable Multiplexing capabilities High-quality, robust and reliable results Proficiency Test Approval (DGKL, Germany)

(This is the suggested replacement for 430289) 2 mL capacity with round bottom These vials do not lock into racks or trays Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Rubber O-ring for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Sterilized by gamma radiation Certified nonpyrogeni…

5 mL capacity with round bottom Black graduations and larger marking spots for easier filling and sample identification Manufactured from polypropylene to withstand temperatures to -196°C Silicone washer for a secure seal Vials may be color coded with inserts (see Cat. No. 430499) Sterilized by gamma radiation Certified nonpyrogenic and DNase/RNase-free

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a binding capacity of approximately 100 to 200ng IgG/cm2 Without lids, lids supplied separately White microplate…

Ultra-Low Attachment Plates feature a covalently bound hydrogel layer that effectively inhibits cellular attachment Surface minimizes protein absorption, enzyme activation, and cellular activation Surface is non-cytotoxic, biologically inert, and nondegradable Nonreversible lids with condensation rings to reduce contamination Individual alphanumerical codes for well identification Uniform footprint for ease in stacking…

Bottles are manufactured from virgin polystyrene, caps from high density polyethyleneBoth resins meet the USP Class VI requirements for plastic containers and closuresTreated for optimal cell attachmentOne piece seamless construction with printed graduationsPrinted lot numbers to aid in product traceabilitySterilized by gamma radiation and certified nonpyrogenic

The MicroClime® environmental lid incorporates a novel, fluid-absorbing matrix that minimizes edge effects and preserves the concentrations of solutions in microplate wells. The absorbed fluid creates a vapor barrier that protects the sample from the exterior environment and from evaporation, greatly reducing edge effects. The MicroClime lids also eliminate edge effects which might occur due to long-term cell incubation, such as…