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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Antisense oligonucleotides

Integrated DNA Technologies Inc.

Antisense oligonucleotides (ASOs) are short oligonucleotides that localize to the nucleus and provide a pathway for gene silencing by the RNase H pathway. Phosphorothioate (PS) linkages are available to confer nuclease resistance and, therefore, enhance intracellular stability.

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