Drug discovery > Target Discovery Products & Reviews

Cell culture medium for establishment and maintenance of mouse pancreatic exocrine organoids

Serum- and BPE-free medium for human airway epithelial cells cultured at the air-liquid interface or as airway organoids

Serum- and BPE-free medium for human airway epithelial cells cultured at the air-liquid interface or as airway organoids

Epigenetic modifier; Inhibits DNA methyltransferase (DNMT)

cAMP pathway activator; Activates cAMP-dependent kinase

Retinoid pathway activator; Activates retinoic acid receptor (RAR) and retinoid X receptor (RXR)

Activin/NODAL/TGF-ß pathway inhibitor; Inhibits ALK5, ALK4, and ALK7

AMPK activator

Tyrosine kinase inhibitor; Inhibits EGFR, HER2, JAK2, JAK3 and STAT5a/b

Epigenetic modifier; Inhibits SIRT2 histone deacetylase

AMPK activator

PI3K/AKT pathway inhibitor; Inhibits AKT1, AKT2, AKT3

PI3K/AKT pathway inhibitor; Inhibits AKT

Retinoid pathway activator; Activates retinoic acid receptor (RAR)

Retinoid pathway activator; Activates retinioc acid receptor (RAR) alpha

Epigenetic modifier; Inhibits histone acetyltransferase (HAT)

Blocks fusion between virus and target host cells

Antioxidant; Reducing agent

MEK/ERK pathway inhibitor; Inhibits B-RAF, B-RAFV600E and C-RAF-1

MEK/ERK pathway inhibitor; Inhibits MEK1 and MEK2

mTOR pathway inhibitor; Inhibits mTOR

Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)

90 kDa ribosomal S6 kinase (RSK) inhibitor

WNT pathway activator; Inhibits GSK3

WNT pathway activator; Inhibits GSK3