Drug discovery > Target Discovery Products & Reviews

ACRO has developed a full range of full-length multi-pass transmembrane proteins with stabilized structure and high activity including CD20, Claudin18.2, CD133, GPRC5D, CXCR4, CCR5 and CCR8.

ACROBiosystems offers a comprehensive collection of recombinant Fc receptor proteins including FcRn FcγRs, FcεRs to expedite antibody drug development and research programs.

Proteins for neuroscience, TAU protein

Proteins for neuroscience, Alpha-Synuclein protein

IL-2 protein and IL-2 receptor proteins

The cannabis industry uses ICP-MS and AA to test for heavy metals. Nitric Acid, Ultratrace from Spectrum Chemical is a strong, highly corrosive mineral acid with extremely low metal content (over 50 with levels less than 100 PPT) ideal for this purpose due to its primary use as an analytical reagent in elemental analysis determinations using ICP and AA techniques, digestion of water samples, and as a doping agent for organic…

Description- Abdos Cryo Vial external thread are manufactured using high purity virgin USP Class VI Medical grade polypropylene (PP) conforming to US FDA 21 CFR, free from natural rubber & heavy metal. Abdos Cryo Vial is designed for long-term cryogenic storage of biological samples, all type of cells and any enzymes or reagents. It’s leak-proof cap design and strong wall thickness makes it an ideal product for transpo…

Made of strong polycarbonate and designed to be used at a temperature between -196°C to 121°C. Can be used in gas phase of liquid nitrogen with appropriate safety procedure in place. Transparent lids permit viewing of contents. These boxes create small, space-efficient storage system within a large mechanical freezer. Lids have numbered grid for sample identification. The surface of the lid has a frosted area suitab…

These racks maintain a temperature of less than 4°C for almost 3.5 hours (with the lid on the rack) at room temperature. Frosty Mate™ can be used for transportation of biological samples, chemicals etc. at a stable temperature for a long time. Consistently cooled samples – FROSTY MATETM color changes dramatically when the temperature of a rack containing samples reaches below 4°C. A clear visible color change from Gre…

Abdos PCR plates are manufactured in state of the art precision moulded facility using high purity virgin USP Class VI Medical grade polypropylene (PP) conforming to US FDA 21 CFR, free from natural rubber and heavy metal. Ultra thin and consistent wall thickness allows precise thermal transfer. Maximum G-Force 4000 RCF. Abdos PCR plates are qPCR compatible. DNase, RNase, Endotoxin and PCR inhibitor free.

Autoimmune disease autoantibody screening. Using the Pan-Autoimmune Protein Array 1.0, Sengenics can screen autoantibodies against more than 100 clinically relevant antigens in a wide range of autoimmune diseases. The Pan-Autoimmune Protein Array 1.0 service is ideal for focused autoimmune disease research.

The BIOne benchtop scale single-use bioreactor (SUB) is for mammalian cell growth, cell therapy, insect cells, and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable headplate welded to a triple-layered liner that can be easily inserted into a non-sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.   

BIOne 1250 Controllers are compatible with both autoclavable and single-use vessels. The systems are also capable of supporting both cell culture and fermentation processes. Standard controller options such as OPC and Additional Input & Outputs expand the capabilities of the controller. Such features provide end-users with nearly limitless process expansion potential for whatever future bioprocesses they desire to engineer.…

The Agilent HLD PD03 Dry Leak Detector uses a mass spectrometer tuned to detect helium, which is used as a tracer gas to locate and/or measure very small leaks in enclosed devices or systems. The compact, multi-use HLD PD03 is both a precise instrument and a robust workhorse, featuring an easy-to-use touch screen interface and menu structure that quickly connect users to powerful capabilities. Built-in application setups short…

Are you looking for additional labware positions and pipetting flexibility? The Avidien Dual Nest can be easily installed on a new or existing microPro to create a third labware position in a compact 96-channel semi-automated benchtop solution.  

The world's smallest 96/384 channel semi-automated benchtop pipettor. This innovative compact instrument packs an enormous feature set that offers unprecedented capability and value. It is accurate, affordable, efficient, reliable and easy to use.

Pooled and Arrayed Genome-Wide LentiORF Libraries for High-Throughput Screens or Targeted Experiments

Recombinant PURedit Cas9 protein from Streptococcus pyogenes is a ready-to-use reagent for genome engineering experiments

Recombinant Cas9 Plus protein from Streptococcus pyogenes is a ready-to-use reagent for genome engineering experiments.

Recombinant Cas9-GFP protein from Streptococcus pyogenes is a ready-to-use reagent for genome engineering experiments.

Trusted TRC (The RNAi Consortium) content with shRNA targting 20,000+ human or 21,000+ mouse genes including TRC 1.5 and 2.0 (unique and validated) add-ons which are exclusive to Sigma

The human CRISPR ′Brunello′ pooled library is designed using optimized metrics, as published by, Doench et al. Nat Biotechnol. (2016) and described further in Sanson, K.R., et al. Nat Commun (2018)

The Human Whole Genome Toronto KnockOut Library v3 (TKOv3) is optimized for editing efficiency using empirical data described in the findings by the Moffat lab.

The human, paired guide Poison (pgPoison) library targets 3` splice sites with paired guide RNAs for alternative exon removal (pgRNAs), induce skipping of "poison" cassette exons and corresponding upstream constitutive exons in ultraconserved regions.

The mouse CRISPR "Brie" lentiviral pooled libraries are designed using optimized metrics, as published by Sanson, K.R., et al. Nat Commun 9, 5416 (2018), which combine improved on-target activity predictions (Rule Set 2) with an off-target score, the Cutting Frequency Determination (CFD)