Drug discovery > Target Discovery Products & Reviews
Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
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Corning® 96-well Clear V-Bottom 0.5 mL Polypropylene Deep Well Plate, 10 per Bag, Nonsterile
Corning Life SciencesFeature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) Certified DNase- and RNase-free Total volume is 500 µL
Atlas Turbidity System
Syrris LimitedThe Atlas Turbidity System is designed for chemists who are interested in monitoring or controlling crystallizations, emulsions, suspensions, etc. The Atlas allows turbidity to be examined and modified by controlling temperature and/or additions to the vessel. Data is displayed on the Atlas Base and can be plotted in real time using the software.
NimbleGen HD2 Catalog Tiling Arrays
RocheSource: UCSC Build: HG18, NCBI 36 Probe Length: 60mer Median Probe Spacing: 1169bp Platform: HD2 Probes per Array: 2,100,000 Feature Size: 13μm x 13μm Array Dimensions: 62mm x 14mm Overall Slide Dimensions: 1" x 3" (25 x 75mm) Recommended Storage: Store arrays desiccated at room temperature.
OpenArray® Endpoint Analysis Software Kit
BioTroveKit includes OpenArray® Endpoint Analysis Software CD and user’s manual. Compatible with the NT Imager or NT Cycler.
OpenArray® Endpoint Analysis Kit
BioTroveCustomer-owned TaqMan® assays reformatted on OpenArray® plates. Plates must be ordered in multiples of 10. Minimum order is 10 plates. Kit includes: Cases, Immersion Fluid, Case Sealing Glue and Plate-File CD.
OpenArray® Human Kinome Kit Version 1.0
BioTroveReal-Time qPCR assays for kinases and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Real-Time qPCR Case, Immersion Fluid, Frame Adhesive and Plate-File CD.
OpenArray® Pathways ADME Panel Kit.
BioTroveOpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for ADME and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Real…
OpenArray® Pathways Apoptosis Panel Kit.
BioTroveOpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Apoptosis and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate,…
OpenArray® Pathways Cancer Panel Kit.
BioTroveOpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Cancer and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Re…
OpenArray® Pathways Cardiovascular Disease Panel Kit.
BioTroveOpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Cardiovascular Disease and related genes reformatted onto an OpenArray plate. Kit includes: Ope…
OpenArray® Pathways Inflammation Disease Panel Kit.
BioTroveOpenArray® Pathways are ready-to-use gene panels containing pre-validated real-time qPCR assays. The plates have over 600 assays each and are compatible with multiple sample types. Panels are currently avaliable with human or mouse genes. New panels are continually under development. Check back for updates. Real-Time qPCR assays for Inflammation and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray pla…
OpenArray® Pathways Signal Transduction Disease Panel Kit.
BioTroveReal-Time qPCR assays for Signal Transduction and related genes reformatted onto an OpenArray plate. Kit includes: OpenArray plate, Real-Time qPCR Case, Immersion Fluid, Frame Adhesive and Plate-File CD.
SIRT1
Cisbio BioassaysAn acetyl-biotinylated substrate recognized by a Eu3+ anti-acetyl MAb and SA-XL665, which is used in activator screening or to test an High Throughput SIRT1 inhibitor. The level of enzymatic activity is inversely proportional to the amount of signal produced in the system. For more information please visit Cisbio Bioassays website.
Reduced breakdown injection port liners
VICI AG InternationalReduced breakdown liners Our improved injection port liner reduces breakdown of endrin and DDT during injections while increasing the interval between liner changes. The problem DDT and Endrin are easily degraded in the injection port; with non-deactivated liners and those filled with non-deactivated glass wool, Endrin breakdown can be as high as 98%. EPA method 8081A states "If degradation of either DDT or Endrin exceeds 15%,…
Anti-miR™ miRNA Inhibitors and Libraries
Thermo Fisher ScientificAmbion Anti-miR™ miRNA Inhibitors are chemically-modified, single-stranded nucleic acids designed to specifically bind to and inhibit endogenous miRNA molecules. These ready-to-use inhibitors can be introduced into cells using transfection or electroporation parameters similar to those used for siRNAs, and enable detailed study of miRNA biological effects.
STN - Online Scientific Database Literature and Patent Search
Chemical Abstracts Service (CAS)STN is an online database service that provides global access to published research, journal literature, patents, structures, sequences, properties, and other data.
Pre-miR™ miRNA Precursor Molecules and Libraries
Thermo Fisher ScientificAmbion Pre-miR™ miRNA Precursor Molecules are small, chemically-modified double-stranded RNA molecules designed to mimic endogenous mature miRNA molecules. These ready-to-use miRNA mimics, which are similar to but not identical to siRNAs, can be introduced into cells using transfection or electroporation parameters identical to those used for siRNAs and enable detailed study of miRNA biological effects via gain-of-function e…
Silencer® Pre-Designed & Validated siRNAs
Thermo Fisher ScientificSilencer Pre-Designed siRNAs are Ambion-designed siRNAs available for all human, mouse, and rat gene targets in the RefSeq database. These siRNAs are designed for maximum potency and specificity using a highly effective and extensively tested algorithm. Each siRNA is synthesized to the highest quality standards and is provided with full sequence information. Silencer Validated siRNAs are Ambion-designed siRNAs that have been…
Silencer® Select Pre-Designed & Validated siRNAs
Thermo Fisher ScientificAmbion Silencer Select Pre-Designed and Validated siRNAs incorporate the latest improvements in siRNA design, off-target effect prediction algorithms, and chemical modifications to yield siRNA with unrivaled efficacy, potency, and specificity. The result is fewer failed experiments due to poor silencing, and cleaner, more consistent phenotypic data.
Silencer® In Vivo Ready siRNAs
Thermo Fisher ScientificAmbion Silencer® In Vivo Ready siRNAs undergo the additional purification and testing necessary for introduction of siRNA into animals. After HPLC purification and annealing, each siRNA is dialyzed to remove salt, sterile filtered, and endotoxin tested. All Silencer Pre-Designed and Validated siRNAs are available in this format, as are Custom Synthesized siRNAs.
Silencer® Select Positive & Negative Control siRNAs
Thermo Fisher ScientificAbmion Validated GAPDH Positive Control siRNA and non-targeting Negative Control siRNAs are available for human, mouse and rat with the same chemical modifications for enhanced efficacy as in other Ambion Silencer Select siRNAs.