Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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TaqMan® Express Plates

Thermo Fisher Scientific

TaqMan® Express Plates are a cost-effective and convenient 96-well format complimenting Applied Biosystem's line of individual TaqMan® Gene Expression Assays, and pre-spotted 384-well TaqMan® Arrays. Customize any of the six available plate formats with dried-down TaqMan® Assays by positioning each in specific well locations. This flexibility enables an efficient means to screen biological samples for the presence and amount…

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TaqMan® Gene Sets

Thermo Fisher Scientific

TaqMan®  Gene Sets are pre-defined lists of genes grouped by pathway or disease target class which can be ordered separately, as a custom plate, or configured directly onto TaqMan®  Arrays to enable you to perform hundreds of real-time PCR reactions simultaneously on the Applied Biosystems 7900HT Fast Real-Time PCR System. Simple to implement, TaqMan Gene Sets are customizable, and when placed on a TaqMan Array, require mini…

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TaqMan® Gene Signature Arrays

Thermo Fisher Scientific

TaqMan®  Gene Signature Arrays enable analysis of hundreds of TaqMan®  Gene Expression Assays on a 384-well micro fluidic card with minimal effort. TaqMan Gene Signature Arrays are readily available and delivered 2–4 days after ordering. They are packaged conveniently with two or four arrays per pack, making them cost effective, and just the right size for any experiment. Choose from pathway-specific pre-defined arrays such…

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TaqMan® MicroRNA Assays

Thermo Fisher Scientific

TaqMan®  MicroRNA Assays quantitate miRNAs with the specificity and sensitivity of TaqMan®  Assay chemistry. A simple, two-step protocol requires only reverse transcription with a miRNA-specific primer, followed by real-time PCR with TaqMan®  probes. The assays target only mature miRNAs, not their precursors, ensuring biologically relevant results. Get gold standard TaqMan Assay performance for miRNA quantitation and profiling…

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TaqMan® PreAmp Pools

Thermo Fisher Scientific

TaqMan® PreAmp Pools are pre-pooled sets of Applied Biosystems TaqMan® Gene Expression Assays ready for use with four specific TaqMan® Gene Signature Arrays. TaqMan PreAmp Pools are designed for challenging RNA samples, such as very small quantities, or degraded material and genes that have low expression levels. Use PreAmp Pools to increase the quantity of your sample targets without introducing bias. Four pools are availab…

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TaqMan® Sample-to-SNP™ Kit

Thermo Fisher Scientific

The TaqMan Sample-to-SNP Kit provides a streamlined protocol for performing TaqMan®  chemistry-based genotyping analysis from any sample with a single kit. The kit is comprised of two parts: the DNA Extract All Lysis Reagents and the TaqMan® GTXpress™ Master Mix. The DNA Extract All Lysis Reagents reduce prolonged procedures for the release of real-time PCR-ready DNA to a 5 minute protocol. They can process a wide variety of…

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Iso-Gold™ Rapid Mouse-Monoclonal Isotyping Kit

BioAssay Works, LLC

The Iso-Gold kit is a rapid-format isotyping kit that reduces the labor of the traditional ELISA kit from a day-and-a-half procedure to a five-minute assay. It determines the isotype of your monoclonal antibody, assess the purity of your purified monoclonal antibody*, verify the purity of your purchased monclonal antibody* and reduces runtime. *multiple lines appear and indicate subclass contamination

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Quattro Premier XE

Waters

Developed for your most demanding LC/MS/MS quantitative applications, the Quattro Premier™ XE tandem quadrupole mass spectrometer features the highest levels of sensitivity, selectivity, robustness, speed and accuracy. To maximize the analytical advantages of your ACQUITY UPLC® System, the Quattro Premier XE operates at the highest data acquisition rates. Together, the ACQUITY UPLC® System and the Quattro Premier XE give you i…

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mTRAQ™ Reagents

Thermo Fisher Scientific

The mTRAQ™ Reagents are duplex amine-specific, stable isotope labeled reagents designed for high confidence protein and peptide biomarker verification using MRM analysis on the QTRAP® system and the triple quadrupole mass spectrometers. * Duplex mass difference tags (Non-Isobaric Amine Tags) * Established chemistry with > 95% labeling efficiency * High selectivity MRM based relative quantitation of proteins/peptides/PTMs * Sup…

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SimGlycan Software

Thermo Fisher Scientific

SimGlycan™ Software (a product of PREMIER Biosoft International) predicts the structure of a glycan from the MS/MS data acquired by AB SCIEX mass spectrometers. It facilitates the study of glycosylation and post translational modifications. The software works directly with *.t2d and *.wiff data generated from AB SCIEX instruments, including the 4800 Plus MALDI TOF/TOF™ Analyzer, 4000 QTRAP® System, and QSTAR® Elite System. * M…

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Osteoprotegerin EIA

Osteoprotegerin (OPG) EIA is an enzyme immunoassay intended for the quantitative determination of OPG in plasma, serum or cell culture supernatants. OPG is a dimeric glycoprotein of the tumor necrosis factor (TNF) receptor family that acts as a soluble receptor for sRANKL (soluble receptor-activated NF-kB ligand) and prevents it from binding to and activating RANK, thus inhibiting osteoclast development. Possible indications f…

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sRANKL (Free) Ultrasensitive EIA

The Ampli-sRANKL EIA is an enzyme immunoassay intended for the quantitative determination of human free soluble RANK-Ligand in plasma, serum and cell culture supernatants. Format:ELISA / EIA, Sample Type:Serum, Plasma, Cell Culture, Sample Size:100 µl, Size:96 Wells, Range:0.125 - 2 pmol/l, Sensitivity:0.02 pmol/l, Incubation Time:Overnight, 1 hour 30 minutes

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Oxidized LDL (Ab) EIA

Oxidized LDL (Ab) EIA is a enzyme immunoassay intended for the quantitative determination of human IgG autoantibodies to oxidized low density lipoprotein (LDL) in serum. Format:ELISA / EIA, Sample Type:Serum, Sample Size:50 µl, Size:96 Wells, Range:37 - 1200 mU/ml, Sensitivity:27 mU/ml, Incubation Time:2 hours 20 minutes

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LPL (Lipoprotein Lipase) ELISA

The LPL (Lipoprotein Lipase) ELISA is an enzyme immunoassay intended for the quantitative determination of human LPL in serum or plasma. LPL is an enzyme that cleaves triglycerides for fatty acid uptake in the periphery. Determination of the LPL concentration might be a complementary measure for LPL activity. Format:ELISA / EIA, Sample Type:Serum, plasma, Sample Size:50 µl, Size:96 Wells, Range:9 - 500 ng/mL, Sensitivity:9 n…

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DKK-1 ELISA

The DKK-1 EIA is an enzyme immunoassay intended for the quantitative determination of human DKK-1 in serum. Format:ELISA / EIA, Sample Type:Serum, Sample Size:15 µl, Size:96 Wells, Range:3.125 - 50 pmol/L, Sensitivity:0.38 pmol/L, Incubation Time:Overnight, 1 hour 30 minutes

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X-Gal-IPTG Spray

Axygen Scientific, Inc.

Axygen X-Gal IPTG spray is a convenient ready-to-use solution of optimal quantities of IPTG, X-Gal and stabilizers presented in a spray bottle for easy, accurate and consistent screening of Blue/White colonies. Advantages of Axygen X-Gal-IPTG Spray include:• Easy, accurate and convenient. • Sprays deliver optimal concentration and volume consistently for consistent and accurate results. • No need to weigh X-Gal and IPTG and…

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Smart Ampicillin™

Axygen Scientific, Inc.

Smart Ampicillin™ from Axygen Biosciences is a specially formulated Ampicillin antibiotic that is optimized for expression studies. Smart Ampicillin is superior to common antibiotics like Ampicillin, Carbenicillin and Methicillin. These regular antibiotics are degraded by enzymes secreted by bacteria over time and the result is the undesirable appearance of satellite or non-recombinant colonies. Smart Ampicillin is specially…

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E-Z Ex-traction® Microtubes

WHEATON

E-Z Ex-Traction Glass MicroTubes are precision engineered and manufactured to have tight tolerances to reduce the chance of failure in automated sample handling and storage systems in compound or biological sample applications.  The barcodes on tubes are 100% readable and never duplicated ensuring perfect data management.  The patented design allows; • each tube to be 2D bar coded; offered with or without permanent 2D barco…

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Microplates Polypropylene

Eppendorf

The Eppendorf Polypropylene Microplates set new standards in terms of transparency, purity and stability! With the easy to read OptiTrack® matrix and a clarity, unique and unbeaten for polypropylene microplates, the identification of the correct plate or an individual well is easier, less error-prone and up to 30 % faster. Do you look for clear signals in fluorescence or luminescence detection even with low concentration sampl…

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Biochrom Amino Acid Analyzer Chemicals

Biochrom Ltd

Biochrom chemicals are manufactured from high quality materials and subjected to rigorous control procedures, under the ISO 9001 Quality System. Our buffers are guaranteed to give accurate and reproducible results for up to 3 years from manufacture, provided the storage conditions are adhered to. All reagents have been formulated so they no longer require cooling, providing stable chemistry with ease of use. Biochrom instrumen…

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Biochrom Anthos 2010 Microplate Reader

Biochrom Ltd

The Biochrom Anthos 2010 Microplate Reader is a great value instrument designed for laboratories requiring a simple basic absorbance reader with PC control as a workhorse. Robust and accurate for even the most demanding endpoint applications such as ELISA for routine assays in research, quality control and diagnostics. All Biochrom Anthos instruments are designed to give reliable results in busy multi-user laboratories for ma…

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DisQuE Dispersive Sample Preparation Kit

Waters

DisQuE Dispersive Sample Preparation is a well proven, high throughput sample preparation method for a wide array of pesticides in produce. The kit contains conveniently packaged vials with pre-measured sorbents and buffers used to provide extraction and clean-up for up to 100 samples. Each 50 mL DisQuE Extraction tube contains 6 grams of magnesium sulphate and 1.5 grams of sodium acetate. Each 2 mL DisQuE Clean-Up tube cont…

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Stem Cell Kits and Panels

Bio-Techne

R&D Stem Cell Kits and Panels Research in developmental biology has led to the discovery of several types of stem cells, including embryonic stem (ES) cells, embryonic germ cells, and adult stem cells. Techniques and reagents developed for the in vitro culture, manipulation and characterization of stem cells provide unprecedented opportunities to study embryology and develop disease treatments. R&D Systems offers the follow…

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Flow Cytometry Kits

Bio-Techne

R&D Flow Cytometry Kit - Flow cytometry kits designed for analysis of cell populations use up to four fluorochrome-conjugated antibodies. Flow cytometry facilitates quantitative, multiparameter analysis of cell populations based on the expression of cell surface and/or intracellular molecules. R&D Systems offers a wide range of biotin-, fluorescein-, phycoerythrin-, or allophycocyanin-conjugated monoclonal antibodies specific…

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