Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
Cell Membranes - Custom Preparation of Cell Membranes from CCS Cell Culture Service Preparations membranes from cell which are expressing a target receptor, transporter or ion channel at a high density are a useful tool in drug research. Embedded in a membrane fragment or vesicle the proteins remain in a functional native confirmation. Ligand binding assay and functional GTP-gammaS assays can be performed with these preparati…
Components of the Upstate (Millipore) Casein Kinase 2 Assay Kit:• Casein Kinase 2 Substrate Peptide (Cat.# 12-330) • Assay Dilution Buffer I (ADBI) (Cat.# 20-108) • PKA Inhibitor Cocktail (Cat.# 20-114) • Magnesium/ATP Cocktail (Cat.# 20-113) • P81 Phosphocellulose Squares (Cat.# 20-134) For use to measure the phosphotransferase activity of Casein Kinase 2 (CK-2) in immunoprecipitates and column fractions based on phosphorylat…
Thermo Scientific* LTQ FT Ultra combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power and versatility. Ultra-high resolution and sensitivity coupled with sub ppm mass accuracy, and MSn are universally available for the toughest applications demanding rigorous structural characterization.
HyClone Classical Liquid Media: BME/EBSS Thermo Scientific HyClone Classical Liquid Media: BME/EBSS is manufactured using ISO 9001:2000-certified processes. High yield cultures begin with high quality media. In order to maintain these standards, all HyClone products as well as raw material components must pass strict Quality Control testing to confirm the appropriate level of quality. Each raw material has a specification docu…
TransIT®-LT1 Transfection Reagent from Mirus Bio- A broad spectrum, low toxicity, DNA transfection reagent • Broad Spectrum DNA Delivery - Utilize one transfection reagent and protocol for a variety of cells. • Low Cellular Toxicity - Maintain cell density and reduce experimental biases. • High Efficiency Delivery - Achieve expression in a large population of cells for experimental success. • Deliver Single or Multiple Plasmi…
The Recording Nanoject II: Enables High Precision Electrophysiological Guidance of Nanoliter Injections into the Brain Features of the Drummond Scientific Recording Nanoject II include:• Facilitates connection to an extracelluar amplifier to allow recording of neural activity • Supplements stereotaxic coordinates in guiding the placement of small injections • Provides direct displacement of neuronal tracer or excitotoxin fro…
SCOPE, Structure-based compound optimization prioritization and evolution is an innovation from VLife to overcome challenges in lead optimization. SCOPE provides the user a way to address known problems like poor correlation between energy and activity, insensitive docking scoring functions for molecule prioritization and insufficient clues in ligand design for improvement in activity. SCOPE smartly understands the information…
R & D Systems Active STAT3 DuoSet IC® Kit - For the development of transcription factor assays to measure human and mouse active STAT1 p91. The R & D DuoSet IC Phospho-specific ELISA format is a sensitive and convenient phosphorylation assay for use with cell lysates. The DuoSet IC signal transduction assays are an excellent alternative to Western blot, especially when used in combination with DuoSet IC ELISAs designed to mea…
R&D Oncostatin MOncostatin M (OSM) is a member of the IL-6 subfamily of cytokines that includes IL-6, IL-11, LIF, CNTF, CLC, and Cardiotrophin-1. These cytokines have overlapping biological functions and shared receptor components. Mouse OSM protein shows 48% amino acid identity with human OSM.
AcroPrep™ Advance filter plates are the newest edition to Pall’s filter plate family. New sealing technology and advanced tip design make these the first choice in critical sample prep applications. Aplications: Lysate Clearance DNA purification Protein purification Multiplex assays Aqueous filtration Particulate removal Size exclusion Bead-based assays Neonatal screening Flow cytometry S…
AcroPrep™ Advance Filter Plates for Ultrafiltration Provides rapid, efficient separation of biomolecules. Omega™ membrane provides high recovery and typically results in > 90% recovery of target biomolecules. New well design results in faster, more uniform filtration rates across the plate with reduced hold-up volume for maximum sample recovery Intrinsic plate and membrane properties prevent target molecules from binding to th…
eArray is a web-based application that enables you to harness the flexibility of Agilents SurePrint oligo manufacturing technology in the creation of custom microarray designs and oligo libraries. eArray, free to all registered users, allows you to create assays that are specific to your research needs. Create custom microarray designs for Gene Expression, microRNA, Model Organisms, CGH, ChiP-on-chip, and DNA Methylation.Crea…
K-Pierce, Auto Plate Seal Pierce.System Specifications: • Desktop Automated Plate Piercing Systems • Seal SBS format micro well plates • Seal plate heights from 9 to 48mm high • Variable force pressure • Easy change pressure pierce heads for different film types requirements • Plate holders supplied for different plate types support requirements due to top surface pressure • Pierce time from 4 plates per minute • 96 or 384 hea…
Using the LiChrolut® extraction unit simplifies solid-phase extraction and makes it more rapid and reliable. The drying attachment speeds up the drying process under controlled conditions. All the individual steps associated with solid-phase extraction can be carried out using the LiChrolut® extraction unit.
Solid-phase extraction for increased productivity: LiChroPLATE® microtiter plates improve the sample throughput and speed of sample preparation. LiChroPLATE® enables solid-phase extraction to be carried out with considerable convenience and flexibility. From sample application with multi-channel pipettors to complete automation of the sample preparation process. Only in this way high sample throughputs can be achieved. LichroP…
Enhanced selectivity for polar analytes: LiChroPLATE® EN microtiter plates for solid-phase extraction shortens sample preparation time up to 75% compared with other polymer phases. By using LiChroPLATE® EN in combination with an 8-channel pipettor, it is possible to extract 96 samples in less than half an hour. EN stands for enhanced selectivity with respect to all polar analytes – whether basic, neutral or acidic. Even for la…
Solid-phase extraction for increased productivity: LiChroPLATE® RP-18 microtiter plates for solid-phase extraction enable ultra-rapid sample preparation with excellent recovery rates and high precision. Up to 96 samples can be processed simultaneously, which means a significant reduction in the time needed for sample preparation and consequent savings on purchasing and disposal costs. The batch-to-batch reproducibility of LiCh…
Frozen membranes from CHO-K1 cells expressing recombinant human Alpha2b Adrenergic receptors. (Cat#: A104)
Frozen membranes from CHO-K1 cells expressing recombinant human FPRL1 N-Formyl Peptide receptors. (Cat#: A121)
Frozen membranes from HEK293 cells expressing recombinant human Thromboxane receptors. (Cat#: A127)
Frozen membranes from CHO-K1 cells expressing recombinant human SST4 Somatostatin receptors. (Cat#: A138)
Frozen membranes from CHO-K1 cells expressing recombinant human SST5 Somatostatin receptors. (Cat#: A139)
Frozen membranes from CHO-K1 cells expressing recombinant human V1a Vasopressin receptors. (Cat#: A149)
