Drug discovery > Target Discovery Products & Reviews

Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Corning® 96-well Clear Polystyrene High Bind Stripwell™ Strips, without Frame or Lid, Nonsterile

Corning Life Sciences

May be used in a variety of laboratory assays Flat bottom strips are designed to easily break apart and may be used in an style strip holder that allows each individual well to be positioned back into the plate once broken High binding surface binds medium (>10kD) and large biomolecules that possess ionic groups and/or hydrophobic regions. Binding capacity is approximately 400 to 500ng IgG/cm2. Ideal for immunoassays Reco…

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Cell Health Profiling V2 Image Analysis BioApplication for Apoptosis and Cytotoxicity

Cell Health Profiling V2 is a flexible image analysis application employing advanced cell-level logic to detect and classify cell health-related events.  It analyzes patterns of cellular fluorescent labeling that can be used to classify cells as undergoing apoptotic, necrotic, or other cell death mechanisms.  This application has been biologically validated, enhancing confidence in your image-based data.  Available for the Cel…

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Cell Cycle V2 Image Analysis BioApplication

The Cell Cycle V2 BioApplication is a sophisticated image analysis algorithm that performs automated analysis of the cell cycle phase of individual and populations of cells.  It reports cell cycle phase as well as the state of up to 3 target proteins for every cell analyzed, and correlates the target data with DNA content.  This application has been biologically validated, enhancing confidence in your image-based data.  Availa…

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HitKit® HCS Reagent Kit - Multiparameter Apoptosis

The Multiparameter Apoptosis Kit comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of cell health by looking at several biological parameters.  This kit specifically labels nuclei, f-actin, and mitochondrial mass/potential in cells.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system.  Available in Evaluation Size (Five…

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Thermo Scientific HitKit® HCS Reagent Kit - Multiparameter Cytotoxicity 1

The Multiparameter Cytotoxicity 1 Kit  comprises three spectrally distinct fluorophores that label cellular targets to allow assessment of cell health by looking at several biological parameters.  This kit contains indicators for nuclei, permeabilized cells, and lysosome mass/pH.  The kit has been validated for use on Cellomics’ ArrayScan® HCS Reader but may be applied to any imaging system.  Available in Evaluation Size (Five…

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MIAS-2 Multimode Microscopy Reader

MAIA SCIENTIFIC

MIAS-2 readers are a new generation of HTS microscopy readers with an unequaled blend of sensitivity, flexibility and speed.  They are designed to cover the throughput and flexibility needs at multiple phases across the R&D value chain.  In drug discovery R&D, applications include target identification, target validation, assay development, high throughput screening, hit-to-lead, deep pharmacology and ADMET.  Unique features…

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MAIA SCIENTIFIC Contract Research Services

MAIA SCIENTIFIC

What is it?  When you plan to access our technology platform, we will assist you in validating  your assay technology  in our platform technology.  Pending on your needs, we will accept your images, your plates with samples or we will create samples according to your protocols. How to use it?  Simply contact us.  What do we do?  Under CDA, we’ll work out with you with a tailor-made work plan for you to evaluate and order.…

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Corning® 96-well Clear Round Bottom Polystyrene Not Treated Microplate, 25 per Bag, without Lid, Sterile

Corning Life Sciences

Not treated (or medium binding) polystyrene surface is hydrophobic in nature and binds biomolecules through passive interactions Is suitable primarily for the immobilization of large molecules, such as antibodies, that have large hydrophobic regions that can interact with the surface Untreated microplates have a binding capacity of approximately 100 to 200ng IgG/cm2 Without lids, lids supplied separately Total volume is…

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DreamFect

OZ Biosciences

Powerful transfection reagent, based on an innovative biochemical method. Next generation of outstanding transfection reagent,  highly efficient, universal and multipurpose.

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PolyMag

OZ Biosciences

For all nucleic acids and all transfection conditions.The universal and powerful PolyMag formulation allows achieving very high transfection efficiency. It is composed by magnetic nanoparticles coated with cationic molecules. Exclusive and optimized PolyMag reagent has been successfully tested with:- All nucleic acids types: naked DNA, RNA, siRNA, ODN, etc…- Cell lines, primary and hard to transfect cells- Adherent and suspens…

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