Drug discovery > Target Discovery Products & Reviews
Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
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Phorbol 12-myristate 13-acetate
Merck KGaA, Darmstadt, GermanyPhorbol 12-myristate 13-acetate is a phorbol ester. It works as a tumor promoter and is involved in gene transcription, cell growth, differentiation, programmed cell death, immune pathway and receptor desensitization via protein kinase C (PKC) signaling pathways. Phorbol 12-myristate 13-acetate is also a model agent to study growth factors-, hormones-, and cytokines-mediated regulation of cellular growth and differentiation.
Poly-D-lysine hydrobromide
Merck KGaA, Darmstadt, Germanymol wt 70,000-150,000, lyophilized powder, γ-irradiated, BioReagent, suitable for cell culture
Poly-L-lysine solution
Merck KGaA, Darmstadt, Germany0.01%, sterile-filtered, BioReagent, suitable for cell culture
Poly-L-ornithine solution
Merck KGaA, Darmstadt, Germanymol wt 30,000-70,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture
Puromycin dihydrochloride from Streptomyces alboniger
Merck KGaA, Darmstadt, Germanypowder, BioReagent, suitable for cell culture