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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Phytocannabinoid Neutrals Mixture 8 (CRM)

Cayman Chemical Co.

Phytocannabinoid Mixture 8 (CRM) (Item No. 34043) is a certified reference material mixture that contains neutral, non-acid, forms of compounds that can be isolated from plants in the genus Cannabis.  Included are Δ9-THC, Δ8-THC, cannabinol, cannabidiol, (±)-cannabichromene, cannabidivarin, cannabigerol, and tetrahydrocannabivarin. It is provided as a DEA exempt preparation in an amber ampule in which the headspace has been p…

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CRISPRi Libraries, Pools, and gRNAs

Merck

Nuclease-independent applications of CRISPR provide equal targeting specificity but instead of cutting, CRISPRi allows for targeted interference of gene function by delivering transcriptional repressor domains to a specific target sequence using modified dCas9 + gRNA complexes. Gene knockdown is complementary to CRISPR-KO and CRISPRa (activation) and has distinct advantages over existing loss-of-function strategies like RNAi.…

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