Epigenetic Analysis Products & Reviews

The NEBNext® ChIP-Seq Library Prep Master Mix Set for Illumina® contains enzymes and buffers in convenient master mix formulations that are ideally suited for sample preparation for next-generation sequencing. NEBNext® reagents are a series of highly pure reagents that facilitate sample preparation of DNA or RNA for downstream applications such as next generation sequencing and expression library construction. The reagents in…

Chromatin immunoprecipitation and DNA methylation assays followed by next generation sequencing is a powerful technique for generating genome-wide profiles of epigenetic modifications and transcription factor binding sites. The SX-8G IP-Star® Compact Automated System provides the flexibility needed to change multiple parameters in the protocols to achieve optimal experimental conditions. Samples generated on the system are…

The GS Junior Titanium Sequencing Kit, combined with the GS Junior Titanium PicoTiterPlate Kit, provides reagents and other consumables required for determining the nucleotide sequence of an immobilized and clonally amplified DNA library, prepared using the appropriate GS Junior Titanium kits. After amplification, the DNA-carrying beads and sequencing reagents are deposited into the wells of the GS Junior PicoTiterPlate (PTP)…

The SeqCap Epi Enrichment System is a set of target enrichment tools for DNA methylation assessment at single-base resolution. SeqCap Epi Kits are available in a variety of product offerings. Depending on your organism of choice and genomic region of interest, there are products cover your needs. Applying concepts similar to those demonstrated by the best-in-class technical performance of the SeqCap EZ products, Roche NimbleG…

Diagenode's High Resolution Library Preparation Kit significantly enhances the resolution of transcription factor binding sites to single nucleotide levels.Using an optimized, proprietary protocol using an exonuclease to digest protein-bound DNA from the 5' end to within a few nucleotides of the protein binding site, the precise location of transcription factor-bound DNA can be determined. The High Resolution Library Preparati…

New insights from beyond the sequence

The EpiScope MSP Kit features a reagent designed exclusively for DNA methylation analysis via methylation specific PCR (MSP). This reagent contains a specific enzyme in an optimized buffer, allowing MSP analyses on bisulfite-treated uracil-containing DNA templates. This kit features high amplification efficiency and methylation specificity compared with standard PCR. The EpiScope MSP Kit is optimized for real-time monitoring…

Diagenode’s Premium RRBS Kit for reduced representation bisulfite sequencing.

KAPA DNA Library Preparation Kits for Illumina sequencing platforms contain evolved and optimally formulated enzymes that enable the highest overall coverage from the least amount of total sequencing. Kits are optimized to achieve significantly higher library yields and contain KAPA HiFi for high-fidelity, high-efficiency and low-bias library amplification. This ensures the highest library and sequence data quality, particu…

KAPA DNA Library Preparation Kits for Ion Torrent sequencing platforms contain evolved and optimally formulated enzymes that enable the highest overall coverage from the least amount of total sequencing. Kits are optimized to achieve significantly higher library yields and contain KAPA HiFi for high-fidelity, high-efficiency and low bias library amplification. This ensures the highest library complexity and sequence data qu…