Reference Materials/Research Services
An innovative technology termed isotopic ratio outlier analysis (IROA) was developed to overcome the analytical challenges associated with current, stable isotope labeled compounds used in untargeted /targeted metabolic profiling. These challenges minimally pertain to analytical variance, artifactual peaks, and metabolite identification. The IROA method uses metabolic incorporation of heavy (95% 13C) and light (5%…
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Assays for methylases, acetylases, phosphorylases and other modifying enzymes involved in histone and chromatin modulation are developed and optimized by RapidFire scientists for primary and secondary screens. Although histone modifying enzymes can be difficult to analyze by traditional methods, label-free RapidFire technology is well suited to this novel and emerging class of targets.
