Biosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.
Biosensing Instrument Inc. introduces an innovative dual-channel electrochemical flow-through SPR option—the EC-DualFlowTM analysis module. This technology provides users with novel capabilities to study molecular binding processes and conformational changes of biomolecules under the influence of applied electrochemical potentials at different flow rates. Its small channel volume facilitates rapid sample exchange and fast kine…
Biosensing Instrument Inc. provides an analysis module for electrochemical surface plasmon resonance research (EC-SPR). The module’s design takes into account the specific needs of high-quality electrochemical measurements while maintaining the high performance of SPR detection. It facilitates simultaneous electrochemical and SPR measurements on the same sensor chip, and is ideal for studying various electrochemical processes…
The quartz crystal microbalance (QCM) is a variant of acoustic wave microsensors that are capable of ultrasensitive mass measurements. Under favorable conditions, a typical QCM can measure a mass change of 0.1-1 ng/cm2. QCM oscillates in a mechanically resonant shear mode under the influence of a high frequency AC electric field which is applied across the thickness of the crystal. Figure 1b shows an edge view of a QCM crystal…
The Stanford Research Systems QCM100 is a low cost quartz crystal microbalance system designed for real-time mass and viscosity measurements in processes occurring at or near surfaces, or within thin films. It comes with controller, oscillator electronics, crystal holder, and three quartz crystals. An external frequency counter and precision voltmeter (not included) are needed to complete the QCM measurement setup. The QCM ser…
The Instrument for Biomolecular Interaction Sensing by imaging Surface Plasmon Resonance (the IBIS-iSPR) is a high resolution SPR-imager that allows for simultaneous detection of hundreds of biomolecular interactions on a single sensor surface. One can see really in real-time ‘what’s going on’! Like a microscope one can view images of the entire sensor surface. Inspection of a microarray which is spotted on the sensor surface…
SPRimager®II ARRAY INSTRUMENT from GWC TEchnologies GWC’s SPRimager®II is designed for analysis of molecular interactions in an array format. The entire array is exposed to the same analyte in the 1-cm flow cell, eliminating the channel-to-channel variability inherent in multichannel systems, and allowing for simultaneous capture of data for all probes on the array.The SPRimager®II uses Surface Plasmon Resonance imaging (SPRi)…
The biosensor sam5 detects and displays biomolecular interactions and kinetics in real time. The central detection unit holds the sensor chip with the parallel execution of up to five different binding experiments. The active temperature control system enables individually adjustable measuring temperatures from 10 to 40°C. In combination with the autosampler this enables a complete series of measurements executed in a fully au…
From BlueSens GmbH, the new combined sensor for bioprocesses combines the parallel measurement of CO2 and O2 with just one space-saving sensor. It can be used for fermenters of every size, from the lab to industrial scale. The BlueInOne Ferm also measures the pressure and humidity in the off gas of the bioprocess. Therefore the BlueInOne Ferm is neither affected by the gas flow nor by humidity in the process. This state-of-the…
From BlueSens GmbH, the thermal conductivity hydrogen sensor BCP-H2 measures any concentration of hydrogen in the shake flask and fermenter. The BCP-H2 can be integrated directly into the gas line and operates independent from the gas flow. Application areas are the chemical industry, biogas plants, agriculture and the Bioprocessing. It can also be used to monitor algal hydrogen production. The reasonably priced BCP-H2 measure…
From BlueSens GmbH comes the BCpreFerm - the whole gas analysis for the scale-up process. Running continuous measurements of the CO2 and O2 contents in shake flasks and fermenters facilitates controlled trial conditions with simultaneous analysis of the metabolic processes. Oxygen or substrate limitations can be detected along with metabolic transpositions. Furthermore, a time specific analysis of the desired product is made p…
