High-content screening (HCS), also known as high-content analysis (HCA), is a high-throughput technique used in drug discovery to identify substances that alter the phenotype of cells. HCS uses fluorescent microscopic imaging and automated image analysis to investigate cellular events such as apoptosis, cell viability, GPCR activation, oxide production, neurite outgrowth, and cell signaling. Find the best fluorescent labeling reagents, cellular assays, and high-content imaging systems in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
The CHEMICON Fibrin Gel In Vitro Angiogenesis Assay Kit provides a convenient system for evaluation of tube formation by endothelial cells in 96-well or other formats. When cultured on top or within a fibrin gel, endothelial cells rapidly align and form interconnecting networks that can display patent lumina2,3. Tube formation is a multi-step process involving cell adhesion, migration, differentiation and growth4. The formatio…
The CHEMICON® In Vitro Vascular Permeability Assay is performed in a 24-well tissue culture plate with 12 cell culture inserts. The inserts contain 1.0 μm symmetrical pores within a transparent polyethylene membrane. The high pore density membranes permit amplified rates of basolateral diffusion with molecules of interest for permeability assays. The membrane is tissue culture treated on both sides for cell growth. Within CHE…
Live cell tracking of single cell or cell population migrationEstablishes a stable and linear concentration gradient that lasts ≥ 48 hoursHelps distinguish chemotaxis from random movementAllows for multiparametric analysis, including cell directionality and velocityEnhanced optical imaging of slow- and fast-migrating cellsAnalyze 3 chemoattractants in parallel for increased throughput and flexibilityNo need to spend time or mo…
The Millicell μ-Angiogenesis activation and inhibition kits provide a powerful, quantitative platform for real-time monitoring of changes in tubule formation with unprecedented optical resolution.Continuous, live monitoring of cells as tubules formEven, flat slide surface prevents any liquid meniscus from forming, eliminating out-of-focus areasFull well visualization at low magnificationOptimized assay conditions in a miniatur…
A Complete Solution for Functional Live Cell Assays Under Controlled Shear Flow—Great for Labs With an Existing Inverted Microscope
Cell Health Profiling V2 is a flexible image analysis application employing advanced cell-level logic to detect and classify cell health-related events. It analyzes patterns of cellular fluorescent labeling that can be used to classify cells as undergoing apoptotic, necrotic, or other cell death mechanisms. This application has been biologically validated, enhancing confidence in your image-based data. Available for the Cel…
The Cell Cycle V2 BioApplication is a sophisticated image analysis algorithm that performs automated analysis of the cell cycle phase of individual and populations of cells. It reports cell cycle phase as well as the state of up to 3 target proteins for every cell analyzed, and correlates the target data with DNA content. This application has been biologically validated, enhancing confidence in your image-based data. Availa…
Optimized for brewing yeast, wine yeast and other small cells with one channel of fluorescence.
The most robust and versatile HCA platform available.
High-throughput single-cell analysis system: analyze hundreds of genes across tens of thousands of single cells in parallel
