Oligonucleotides Products & Reviews

Oligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.

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Glen-Pak

Glen Research

Glen-Pak™ cartridges utilize the 5’ DMT retained on an oligonucleotide to specifically bind full-length sequences to the support. During the purification process, the failure sequences are eliminated and the DMT is subsequently removed, allowing for elution of purified product.

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MGB Eclipse® CPG

Glen Research

MGB Eclipse ® pairs a minor groove binding (MGB) tripeptide with a dark quencher. The MGB significantly enhances hybridization, while the Eclipse ® has a broad absorption range that quenches many of the most common fluorophores, including FAM, HEX, TET and Yakima Yellow ® .

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