Electrophysiology is the study of biological voltage changes, from a single ion channel through to a whole organ scale. Voltages can be measured using patch clamping, automated workstations, electrophysiology rigs or cell based assays. Specific cell lines, manipulators and microinjectors are also available for electrophysiology research.
Triple EmissionThe TripleSplit 3-way image splitter from Cairn Research is a simple device for dividing an image into either one, two or three separate, spatially equivalent components which can be displayed side by side on a single camera chip. Download data sheet Splitting is usually performed on the basis of wavelength or polarisation, allowing applications where there is a requirement for simultaneous, or high speed, acqui…
Our New LED Based Flash Photolysis SystemThe Cairn Optoflash is the latest member of the Cairn OptoLED family. It uses our established LED head and microscope coupling designs, but is optimised for short-term intense illumination. This makes it particularly suitable for the photoactivation of “caged” neurotransmitter or other compounds, and for the important emerging application of channel rhodopsin activation. The maximum cur…
Ultra Stable and Instantaneous Wavelength Switching Recent developments in Light Emitting Diode [LED] technology have yielded devices that are both brighter and capable of operating at more different wavelengths than their predecessors. The high stability and absence of harmful ultraviolet and infrared radiation makes them an ideal choice for fluorescence and transmitted light microscopy. In common with our OptoLED, the Lite v…
Our flexible LaserBank system will launch up to five laser lines into up to five different single-mode fibres. This system can be configured with new lasers or, in most cases, with existing solid state lasers. Please contact us for details of your requirements. The flexible architecture allows lasers to be mounted for TIRF, FRAP, photolysis, confocal or widefield imaging. It provides analogue intensity control and digital swit…
Adjustable field mask for region selection For many years we have offered a movable variable rectangular field stop. This was initially designed to mask a region of interest within the field of view of a microscope in order to make localised intensity measurements with a photomultiplier. Subsequent evolutions of the device have formed an integral part of our OptoSplit image splitters to mask a region to be projected to both ha…
LumiScope for the detection of bioluminescence from aequorin and other luminescence probes.
The PatchPro systems are fully integrated patch clamping solutions that work in conjunction with fixed stage nosepiece focussing scopes from Olympus, Zeiss, Nikon and Leica. They allow the user to control manipulators, microscope platforms, microscope focus and temperature control all from one neat, simple user console. With the versatility to freely combine numerous individual devices, the PatchPro systems will be perfect for…
Crucial for every experimental setup is a stable mounting system. The Scientifica range of slice platforms, top plates and microscope stages has been developed for researchers using upright or inverted microscopes who would like to move outside the field of view of the objective. Various configurations can achieve this in different ways, either by translating the entire microscope between fixed apparatus, or where laser inputs…
The SliceMate is a temperature controlled submerged recording chamber for biological samples; neatly housed in one compact unit. It utilizes cutting edge technology to give outstanding temperature control in a compact, easy and convenient package which replaces the clumsy, slow reacting and problematic water bath designs. A peltier element allows you to heat or cool the solution whilst a data file of the actual temperature is…
The LBM-7 was designed and developed in conjunction with scientists to be stable, have low drift and be easy to use. It bridges the gap between coarse manipulators and micromanipulators. Affectionately known as the Little Blue Manipulator, this device can be easily configured from left to right-handed. With seven axes of movement, four linear and three rotational, combined with micron resolution, the LBM-7 was designed to serv…
