DharmaFECT Transfection Reagents
Tailored transfection reagents for a wide variety of RNA and cells. High-efficiency delivery, low cellular toxicity, broad dynamic range
RNA Interference Products & Reviews
RNA interference (RNAi) uses siRNA or miRNA for transcriptional silencing, gene knockdown and regulation of gene expression. RNAi requires chemical synthesis, introduction of DNA vectors into cells, an assay of RNAi effects and RNAi quantification or analysis. Consider target sequence selection, reagent preparation, controls, high specificity and effectiveness and low non-specific gene knockdown.
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RNAi Controls
Crucial to any gene silencing or microRNA modulation experiment. RNAi controls allow accurate interpretation for reliable, reproducible results.
SMARTvector Inducible Lentiviral shRNA
Tightly controlled gene silencing with the most advanced and flexible single-vector inducible shRNA.
MISSION® shRNA Clones
MerckThe largest and most validated shRNA collection from the RNAi consortium (TRC). Merck's unique shRNA formats leverage the discovery potential of the trusted and proven TRC shRNA collection. When you partner with them, you gain access to their world class lentiviral production expertise and the formats and specifications for RNAi knockdown experiments at any scale.
MISSION® TRC Arrayed shRNA Library
MerckTrusted TRC (The RNAi Consortium) content with shRNA targting 20,000+ human or 21,000+ mouse genes including TRC 1.5 and 2.0 (unique and validated) add-ons which are exclusive to Sigma
MISSION® pLKO.1-puro Empty Vector Control Plasmid DNA
MerckThe MISSION pLKO.1-puro Control Vector is a lentivirus plasmid vector. The vector does not contain an shRNA insert and is useful as a negative control in experiments using the MISSION shRNA library clones.
MISSION® Human Kinase Lentiviral shRNA Pool
MerckThe MISSION pLKO.1-puro Control Vector is a lentivirus plasmid vector. The vector does not contain an shRNA insert and is useful as a negative control in experiments using the MISSION shRNA library clones.
MISSION® TRC3 Human Lentiviral ORF Pool
MerckDeveloped at the Broad Institute, the MISSION ® TRC3 human whole genome pooled ORF library consists of over 17,000 unique ORF clones, encoding for over 14,000 genes used for overexpression screening