Metabolism Assays Products & Reviews

The only kit you’ll need to build your own organ-on-chip

The open organ-on-chip platform

SOD or SOD-like activity detection.  WST-1 based SOD inhibition assay, colourimetric microplate measurement, measures 100% inhibition by SOD, pH-independent IC50 determination, low background noise measurement.

A novel, far-red fluorescing dye that reveals hypoxic experience of individual cells.

Cell permeable dye to detect metabolic activity in cells.

Cell viability and vitality kit to measure metabolic activity and dead/non-viable nucleated cells with Hoechst to determine total nucleated cell count.

Determine metabolic activity of Lager and Ale yeast.

The Glucose-Glo™ Assay is a bioluminescent assay for rapid, selective and sensitive detection of glucose in biological samples.

The GSH/GSSG-Glo™ Assay is a bioluminescent assay to detect and quantitate total glutathione ratios.

The Caspase-Glo ® 1 Inflammasome Assay  directly measures inflammasome activation with a simple add-mix-measure protocol.

Exogenous volatile organic compound probes (EVOC Probes) enable targeted, non-invasive assessment of biological pathways. Probes are safe, easy to administer compounds that interact with characterised metabolic pathways with relevance to key disease areas. Using Breath Biopsy, EVOC Probes can be monitored non-invasively on breath, either alone or in parallel with biomarker discovery studies.

CYRIS monitors and analyzes several key cellular parameters in real-time and label-free. Cell viability, metabolism, and morphology can be screened in a fully automated and atmosphere-controlled environment. The incubator integrated solution measures oxygen, pH, and cellular impedance in a multiwell plate and makes through a digital inverse microscope phase-contrast like live-cell images.

A push-button solution to analyze lipid droplet dynamics, label-free.

BC001 - 2-channel biochip with narrow cavities for organ-on-chip models by Dynamic42

BC002 - 2-channel biochip with wide cavities for organ-on-chip models by Dynamic42

BC003 - 3-channel biochip with cavities for spheroid/ organoid-on-chip models by Dynamic42

BC005 - 2-channel biochip with thin channels for organ-on-chip models with limited cell material by Dynamic42

In 2008 Gentronix launches a new S9 protocol to extend the application of the GreenScreen HC assay to include the detection of genotoxic metabolites. Many pharmaceuticals only present a genotoxicity hazard after metabolism and such chemicals are called pro-mutagens or pro-genotoxins. Generally, although not exclusively, the liver is considered responsible for the “metabolic activation” (MA) of promutagens. However, none of t…

The iNOS Activation Kits measure cytoplasmic induction of the iNOS enzyme via activation of one of the many inflammatory pathways.

BlueScreen HC uses a single cell strain, which permits 8 compounds to be tested across 8 dilutions (2-fold serial), together with untreated and positive controls, in one 96-well microplate. After arraying test compounds and dilutions, growing cells are added to each well. For studies without S9 metabolic activation data are collected after incubation (48h) using a multimode microplate reader. For studies incorporating S9 metab…